Paul E. Casey, MD, MBA, FACEP

Senior Vice President and Chief Medical Officer, Rush University System for Health  

Professor, Department of Emergency Medicine, Rush University Medical Center  

Paul Casey, MD

Paul Casey serves as the system chief medical officer for Rush University System for Health. In addition to leading quality strategy for the system, he leads the digital strategy as well as enterprise pharmacy and laboratory operations.  

Under Casey’s leadership, Rush has set the nation’s standard in health care quality and safety, modeled excellence in clinical leadership both regionally and nationally, and maintained its deep and long-standing commitment to health equity.

Vizient ranked Rush University Medical Center No. 6 among 107 academic medical centers for quality and accountability in 2025 and has ranked Rush in the top 10 for 13 consecutive years. The medical center has earned a spot on the U.S. News & World Report Best Hospitals Honor Roll six consecutive times.  

Casey is also an emergency medicine physician, board certified clinical informaticist and a professor in the Department of Emergency Medicine at Rush.  

Casey was instrumental in spearheading Rush's nationally lauded COVID-19 response strategy, rapidly mobilizing Rush for the treatment and testing of patients. As the physician director of Rush's COVID-19 Hospital Incident Command Center, he oversaw clinical preparations for novel 2019 coronavirus cases and managed ongoing clinical operations related to the pandemic. Casey is a sought-after speaker at a number of national conferences and a member of national leadership committees including the Vizient Medical Executive Steering Committee and the AAMC Chief Medical Officers committee.

Prior to being named Rush’s chief medical officer, Casey served in various roles including as associate chief medical officer, senior patient safety officer, associate chief medical informatics officer and as vice chairperson for Emergency Department Operations. During his tenure as chief medical officer, Casey also served as the interim president for Rush University Medical Group for two years prior to the launch of the integrated system medical group.

Casey earned his medical degree from Loyola University Stritch School of Medicine and completed his residency in both emergency and internal medicine at the University of Illinois at Chicago Medical Center. He is board certified in emergency medicine, internal medicine and medical informatics. Casey also completed an MBA at the Isenberg School of Management at the University of Massachusetts at Amherst.