Clinical Trials and Studies
Rush participates in clinical trials across a wide range of specialties, discovering breakthrough treatments for cancer, neurological disorders, heart disease and more.
B
Blood Disorders and Hematologic Cancers
- A Prospective, Observational Cohort Study of Participants at Risk for Chronic Graft-Versus-Host Disease in the United States (THRIVE)
- A Study for Patients with Large B-Cell Lymphoma Who have Completed Initial Therapy
- Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease Treatment Study
- Cold Agglutinin Disease Real World Evidence Registry
- Drug Treatment Study for Children with Hemophilia A
- Evaluation of Pediatric Palliative Inpatient Process
- Expanded Access Protocol (EAP) for Subjects Receiving Lisocabtagene Maraleucel
- Health Literacy and Numeracy in Adolescent Patients with Hemophilia A and B Study
- Hemophilia A or B Treatment Study
- Hemophilia A Treatment Study
- Luspatercept versus Placebo in Subjects with Myeloproliferative Neoplasm-Associated Myelofibrosis
- Mastocytosis Patient Registry
- Molecular and Clinical Biology of von Willebrand Disease Study
- National Registry of All Persons with Bleeding and Clotting Disorders
- Newly Diagnosed T-Lymphoblastic Leukemia and T-Lymphoblastic Lymphoma Treatment Study
- Public Health Surveillance for the Prevention of Complications of Bleeding and Clotting Disorders
- Study for Subjects with Multiple Myeloma
- Study of Biomarkers in Hemophilic Arthropathy
- Study of Hepatitis C Virus Outcomes After Treatment in Patients with Bleeding Disorders
- Study Treating Patients With High-Risk Smoldering Myeloma
- Treatment Option for Relapsed or Refractory Multiple Myeloma
- Treatment Study for Children with Hemophilia B
- Treatment Study for Newly Diagnosed High Risk B-Lymphoblastic Leukemia in Patients with Ph-like TKI Sensitive Mutations
- Treatment Study for Patients with Localized Central Nervous System Germ Cell Tumors
- Treatment Study for Patients with Newly Diagnosed B-Lymphoblastic Leukemia or B-Lineage Lymphoblastic Lymphoma
- Treatment Study for Pediatric Patients with Hemophilia A
- Treatment Study for Subjects with Severe Hemophilia A or B
- Treatment Study for Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
Brain Tumors
- Meningioma Drug Treatment Study
- NRG-CC014: Comparing Radiation Therapy to Usual Care for Patients with High-Risk Bone Asymptomatic Metastases, PREEMPT Trial
- Observation or Radiation Therapy in Treating Patients with Newly Diagnosed Grade II Meningioma that has been Completely Removed by Surgery
- Randomized Phase II Trial of Anti-Lag-3 and Anti-PD-1 Blockade vs. SOC in Patients with Recurrent Glioblastoma
- Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
- Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients with Cancer that has Spread to the Brain
Breast Cancer
- De-Escalation of Breast Radiation Trial (DEBRA)
- E-Mindfulness Approaches for Living After Breast Cancer (HEAL-ABC)
- ELEGANT/STML-ELA-0422 Study for Breast Cancer Patients
- Estrogen Receptor Status Study
- Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25 (OFSET)
- MK2870-010
- NSABP B-63/ASCENT-05/GS-US-595-6184
- NSABP B-64/ EXActDNA-003 Breast Cancer Clinical Validation Study
- NU 23B05 for Patients with ER-Positive/HER2-Negative Advanced or Metastatic Breast Cancer
- ReDiscover-2 / RLY-2608-102
- Scalp Cooling for Breast and Ovarian Cancer Patients
- Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer
- Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer (SCARLET)
- Study of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer (TAILOR RT)
G
Gastrointestinal Cancers
- Act Fast Study for Patients with Colorectal Cancer or Colorectal Lesion
- Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)
- EXtending outcomes for PAncreas cancer patients with Nominal oligometastatic Disease (EXPAND): A Randomized Phase III Trial
- Initial Feasibility Study to Treat Pancreatic Cancer With a Planar LDR Source
- Pancreatic Cancer Screening Study
- Refractory Small Bowel Adenocarcinoma Treatment Study
- Retrospective Chart Review of Patients with Fibrolamellar Carcinoma
- Study of Eating Patterns and Alcohol Consumption in Patients with Advanced Tubular Adenoma
Genitourinary Cancers
- Chemoradiotherapy Study for Patients with Localized Muscle Invasive Bladder Cancer
- EA8191: INDICATE
- NRG-GU014: Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
- Prostate Cancer Study
- STRIKE
- Study of Standard Systemic Therapy in Treating Prostate Cancer
- The ICONIC Trial for Rare Genitourinary Cancers
- The PROBE Trial: Treatment Study for Metastatic Kidney Cancer
- Treating Participants With Metastatic Prostate Cancer
- Treating Patients With High Risk Prostate Cancer
- Treatment Study for Patients With Muscle-Invasive Bladder Cancer
- Treatment Study for Rare Genitourinary Cancers
Gynecologic Cancers
- A Single-Arm, Phase 2 Study of Neoadjuvant Carboplatin and Mirvetuximab Soravtansine in Subjects with FRα-Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer
- C5721005/GOG-3116 Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
- Non-Treatment Study for Patients with Ovarian Cancer
- Scalp Cooling for Breast and Ovarian Cancer Patients
- Study to Compare Two Surgical Procedures in Women With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
H
Head and Neck Cancer
- Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
- HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer Treatment Study
- Testing Immunotherapy Versus Observation in Patients with HPV Throat Cancer
- The MCLA-158-CL02 Study for Patients with Head and Neck Cancer
- Treatment Study for Squamous Cell Carcinoma of the Head and Neck
L
Lung and Chest Tumors
- A Study of Ifinatamab Deruxtecan versus Treatment of Physician's Choice in Subjects with Relapsed Small Cell Lung Cancer (IDeate-Lung02)
- A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants with Idiopathic Pulmonary Fibrosis
- ALCHEMIST Chemo-IO Study: Treatment for Treatment for Non-Small Cell Lung Cancer
- An ALCHEMIST Treatment Trial: Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer
- Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
- Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
- Prolonged Air Leak (PAL) Autologous Blood Patch Intervention Trial
- Pulmonary and Critical Care Registry
- S1900G : Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
- Study of First Line Treatment and Maintenance in Non-Small Cell Lung Cancer
- TETON Study: Inhalation Treatment for IPF
- The Lung Health Cohort Study
- Treatment Study for Common EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer