Initial Feasibility Study to Treat Pancreatic Cancer With a Planar LDR Source

Clinical Trial Title

Safety and efficacy of permanently implantable LDR CivaSheet® in combination with external beam radiation in the treatment of pancreatic cancer.

Contact Information

Rush Cancer Center Clinical Trials Office

Clinical Trial Protocol Description:

This is a feasibility study to determine the safety and efficacy of a new brachytherapy device that provides unidirectional radiation which utilizes active components (Palladium-103) of standard devices in a novel configuration. This pilot study may benefit pancreatic cancer patients by reducing the radiation dose to adjacent critical structures, while giving a therapeutic dose to diseased tissue, such as at a surgical margin. The appropriate dose and local control rate will be recorded the primary endpoint in order to provide an efficacy assessment.

Clinical Trial Eligibility Criteria:

In order to participate you must meet the following criteria:

  • Are capable of undergoing anesthesia.
  • Have been selected to undergo Whipple procedure.
  • Do not have metastatic disease.
  • Have suspected R0 or R1 margins.
  • Have no prior radiation therapy to the region for separate cancer.
  • Have a confirmed diagnosis of borderline resectable or locally advanced pancreatic adenocarcinoma.

This is a partial list of eligibility requirements.

Study Details

Clinical Trial Investigator

Dian Wang, MD, PhD

Contact Information

Rush Cancer Center Clinical Trials Office


RUSH University Medical Center

1620 W Harrison St
Chicago, IL 60612

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