COVID-19 Study for Vaccination and Immune Response

Clinical Trial Title

SARS-CoV-2 Immune Responses After COVID-19 Therapy and Subsequent Vaccine

National Clinical Trial Number:


Contact Information

ID Research Team

Clinical Trial Protocol Description:

This study is for people who have not previously had a COVID-19 infection. The study is designed to evaluate how the immune system responds to mRNA-COVID-19 vaccines in these participants. The safety of mRNA COVID-19 vaccines in persons with prior COVID-19 who did and did not receive prior experimental treatment for COVID-19 will be explored. Prior infection with or without treatment could increase, decrease, or have no significant effect on the response to mRNA COVID-19 vaccines, as well as the risk of side effects from these vaccines. Immune responses of participants who have not previously been infected with COVID-19 will be compared to those who have previously had COVID-19.

Clinical Trial Eligibility Criteria:

In order to participate you must meet the following criteria:

  • Are 18 years of age or older.

You will be excluded from the study if any of the following criteria apply to you:

  • Have a history of a COVID-19 infection.
  • Have a previous COVID-19 vaccination of any kind. 

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.

Study Details

Clinical Trial Investigator

Mariam Aziz, MD

Contact Information

ID Research Team


Rush University Medical Center

1620 W Harrison St
Chicago, IL 60612

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