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Parkinson's Disease — Clinical Trials

INSIGHTS Study: Investigational Drug Treatment for Patients with Advanced Parkinson's Disease

INSIGHTS study: An open-label, randomized 26-week study comparing levodopa-carbidopa INteStInal gel (LCIG) THerapy to optimized medical treatment (OMT) on non-motor symptoms (NMS) in subjects with advanced Parkinson's disease.

Medication Treatment Study for snOH in Subjects with Primary Autonomic Failure

Phase 3 clinical effect of TD-9855 for treating snOH in subjects with primary autonomic failure.

Parkinson's Disease and Levodopa-Induced Dyskinesia Treatment Study

Study of how well a study drug called dipraglurant (ADX48621) works compared to placebo in patients with Parkinson’s disease (PD) and levodopa-induced dyskinesia (LID).

Study of Diet-Microbiome Interactions and Parkinson’s Disease

Diet-microbiome interactions and Parkinson’s disease.

Study of Genes Associated with Parkinson’s Disease

Study of genes associated with Parkinson’s disease (PD) from people all over the world.

Study to Determine the Changes in Cognition in Patients with Parkinson’s Disease

Study to identify genetic forms of Parkinson’s disease and determine how cognition changes in these subjects.

Tempo-1 Trial: Parkinson’s Disease Treatment Study

A phase 3, double-blind, randomized, placebo-controlled, parallel-group, 27-week trial to evaluate the efficacy, safety, and tolerability of two fixed doses of tavapadon in early Parkinson’s disease (Tempo-1 trial).

Treatment Study for Idiopathic Parkinson’s Disease

A phase 2 study to evaluate the safety, tolerability and initial efficacy of pramipexole ER, given with aprepitant in patients with idiopathic Parkinson’s disease.

Treatment Study for Parkinson's Disease Patients with Motor Fluctuations

A randomized controlled study to compare the safety and efficacy of IPX203 with immediate-release carbidopa-levodopa in Parkinson’s disease patients with motor fluctuations. (Protocol No.: IPX203-B16-02)

Treatment Study for Patients with Neurogenic Orthostatic Hypotension

A clinical study of patients with symptomatic neurogenic orthostatic hypotension to assess sustained effects of droxidopa therapy (RESTORE).