Study to Determine the Changes in Cognition in Patients with Parkinson’s Disease

Clinical Trial Title

Study to identify genetic forms of Parkinson’s disease and determine how cognition changes in these subjects.

Contact Information

Gian Pal, MD, MS

Clinical Trial Protocol Description:

The purpose of this study is to determine the changes in cognition over time in Parkinson’s disease patients with and without mutations in the glucocerebrosidase (GBA) gene. 262 patients will be recruited for this study in the Chicago area over a 5 year period.

Clinical Trial Eligibility Criteria:

In order to participate you must meet the following criteria:

  • Have developed Parkinson’s disease symptoms under the age of 60.
  • Have had Parkinson’s disease for at least 5 years.
  • If you have had deep brain stimulation, your surgery must be within the past 2 years.

You will be excluded from the study if any of the following criteria apply to you:

  • Have severe dementia.

This is a partial list of inclusion and exclusion criteria.

Study Details

Clinical Trial Investigator

Gian Pal, MD, MS

Contact Information

Gian Pal, MD, MS

(312) 563-2900


RUSH University Medical Center

1620 W Harrison St
Chicago, IL 60612

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