TRUST Study

Patients with suspected intermediate-high risk acute pulmonary embolism (PE) who are eligible for treatment using the Laguna Thrombectomy System for percutaneous mechanical thrombectomy. All subjects are followed for 30 days after the procedure. Safety and efficacy measured by monitoring major events and reduction in RV/LV ratio pre- to post-procedure.

In order to participate you must meet the following criteria:

• Have clinical signs and symptoms of acute intermediate- high risk PE within 14 days confirmed by CTA imaging.
• Present with a filling defect in at least one main or lobar pulmonary artery and RV/LV ratio of > 0.9 as determined by CTA.

You will be excluded from the study if any of the following criteria apply to you:

• Have active cancer and are receiving chemotherapy or radiation treatment during the course of the study.
• Have a known anaphylactic reaction to radiographic contrast agents that cannot be pretreated or have any absolute contraindication to systemic or therapeutic dosage of heparin or anticoagulants.

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.