Clinical Trial Title
REal World ExperieNce With BRIUMVI® (UblituximAB-xiiy) Treated Patients: A Longitudinal REgistry Study (ENABLE)National Clinical Trial Number:
NCT06433752Contact Information
Clinical Trial Protocol Description:
The purpose of this study is to evaluate safety, effiectiveness, and to gain insight into the treatment experience of participants prescribed BRIUMVI® (ublituximab-xiiy) in the real-world setting.
Clinical Trial Eligibility Criteria:
In order to participate you must meet the following criteria:
- Have a confirmed multiple sclerosis (MS) diagnosis.
- Have not received any BRIUMVI® (ublituximab-xiiy) infusion prior to study start. Participants who have been prescribed BRIUMVI® (ublituximab-xiiy) but have not yet received their first infusion on Day 1 of 150 milligrams (mg) can be included.
You will be excluded from the study if any of the following criteria apply to you:
- Have received any live or live-attenuated vaccines (including for varicella-zoster virus or measles) within 4 weeks prior to first BRIUMVI® (ublituximab-xiiy) administration or any non-live vaccines within 2 weeks prior to first BRIUMVI® (ublituximab-xiiy) administration.
- Have any active infection (e.g., active Hepatitis B virus [HBV]).
- Have concurrent participation in any interventional MS trials, or planned concurrent treatment with other Multiple Sclerosis Disease Modifying Therapy (MS DMT) during the study period.
This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.
Study Details
Clinical Trial Investigator
Fabian Sierra Morales, MD
Contact Information
Shamama Sarwar, MD, CCRC
Clinical Trial Location
Rush University Medical Center