The Gut Microbiome During HIV Infection

Clinical Trial Title

Glycomic Modulation of Gut Microbiome During HIV Infection

Clinical Trial Protocol Description:

The purpose of this study is to evaluate the microbiome of human immunodeficiency virus (HIV+) individuals currently treated with ART (antiretroviral therapy) treatment. Participants are asked to complete an at-home stool collection kit, online questionnaires, a blood draw, and a colonoscopy with biopsies.

Clinical Trial Eligibility Criteria:

In order to participate you must meet the following criteria:

For HIV+ ART-treated participants:

  • Are 18 to 65 years of age.
  • Are infected with HIV-1.
  • Have been on ART for at least 12 months.
  • Have had no change in ART for at least three months

For HIV- participants:

  • Are 18 to 65 years of age.
  • Have been matched to the HIV+ ART-treated group (age (+/- 5 years), gender, ethnicity, smoking, and body mass index (+/-3)). 
  • Have a scheduled colonoscopy at Rush University Medical Center.

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.

Study Details

Clinical Trial Investigator

Ali Keshavarzian

Gabriella Sanzo