Clinical Trial Protocol Description:
Deep brain stimulation (DBS) is a medication-free therapy that delivers small pulses of electricity deep within the brain. DBS involves a surgical procedure during which thin wires (called leads) are placed in the brain and connected to a stimulator that is typically placed within the chest. The stimulator device is like a pacemaker, and it sends electrical pulses to an area of the brain called the subcallosal cingulate to regulate the signals thought to help reduce the symptoms of depression. The study will require regular visits over 3 years. Participants are assigned by chance to one of two treatment groups: active stimulation (the DBS system is activated after it is implanted) or delayed stimulation (the DBS system is activated 12 months after it is implanted).
Clinical Trial Eligibility Criteria:
In order to participate you must meet the following criteria:
- Are 22 to 70 years of age.
- Have been diagnosed with depression and are currently experiencing symptoms of depression for at least 12 months.
- Have tried at least 4 treatments and not found them helpful.
- Are able and willing to get records from your psychiatrist.
This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.
Study Details
Clinical Trial Investigator
Contact Information