BOOMBOX: Master Study

The goal of this observational study is to collect information on the use of the HistoSonics Edison System for the treatment of liver tumors. The study will collect information about participants before, during, and after the histotripsy treatment procedure. All participants will be followed per standard clinical follow-up for up to 5 years after the initial histotripsy procedure.

In order to participate you must meet the following criteria:

• Are ≥22 years of age with a diagnosis of: primary (e.g., HCC, cholangiocarcinoma, angiosarcoma) or metastatic (from other primary cancers) liver cancer, or benign liver tumors (e.g., adenoma).
• Your liver tumor(s) can be partially or completely treated with histotripsy.

You will be excluded from the study if any of the following criteria apply to you:

• Are enrolled in an interventional HistoSonics-sponsored trial.
• Have a concurrent condition that, in the investigator's opinion, could jeopardize the safety of the subject or compliance with the protocol.

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.