Surgical Management of Post-Traumatic Occipital Migraines Study

Clinical Trial Title

Surgical management of post-traumatic migraines on maximal medicine therapy.

Contact Information

Research Coordinator

Clinical Trial Protocol Description:

The purpose of this study is to determine if there is any superiority of one of the two current standard-of-care surgical treatments for often debilitating post-traumatic occipital migraines. These procedures involve freeing up or removing one or more of the occipital nerves deemed to be the source of these headaches. This is a single institution study at Rush University Medical Center, and there will be 25 patients enrolled in each study arm. The two standard-of-care procedures will be assigned to the study population randomly.

Clinical Trial Eligibility Criteria:

In order to participate you must meet the following criteria:

  • Have a history of sharp or blunt head or neck trauma or a concussion as an inciting event for occipital headaches.
  • Have chronic headaches occurring in the occipital distribution (back of head) for over 1 year, as diagnosed by neurologist.
  • Are between 18 and 65 years of age.
  • Are male or female.

You will be excluded from the study if any of the following criteria apply to you:

  • Have a headache of any etiology other than specified in the inclusion criteria.
  • Have occipital referral of pain arising from the atlantoaxial or upper zygapophyseal joints or from tender trigger points in neck muscles or their insertions.
  • Are a pregnant or breastfeeding.
  • Have significant comorbidities including short life expectancy, malignancy, degenerative central nervous system diseases, infection, severe psychiatric disorders.

This is a partial list of inclusion and exclusion criteria.

Study Details

Contact Information

(312) 563-3000


RUSH University Medical Center

1620 W Harrison St
Chicago, IL 60612

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