A New Type of Asthma Study for Patients with Severe Asthma

Clinical Trial Title

PrecISE: Precision Interventions for Severe and/or Exacerbation-Prone Asthma

National Clinical Trial Number:


Contact Information

Clinical Trial Protocol Description:

This individual-based care is called precision medicine, a new approach to care based on someone’s medical history, where they live, and profile (age, gender, and so on). We will use precision medicine to understand treatments for severe asthma. These treatments are not yet used for asthma today. Study participants will be a part of pioneering work for asthma treatment.

We have two goals for the PrecISE study:

  1. Make it easier to identify different types of severe asthma.
  2. Understand the best ways to treat these different types of severe asthma.


You will first go to a clinic to complete screening visits where you will tell us more about yourself and receive medical tests. Screening visits can take about 2-4 hours and may be split over different days.

If you are eligible for the study, you will take part in treatment visits (about 3 hours each). At these visits, we do medical tests and give you study treatments to take home and use.

Study Commitment

The length of time you are in the study will range from 1 to 3.5 years, and it will depend on when you enroll. If you enroll early in the study, and qualify for each individual treatment, you could receive up to 5 treatments.

Home Activities

We will ask you to spend time at home taking measurements and tracking how study treatments affect your asthma.


Your time is valuable. Time slots for these visits will be flexible, and you will receive appointment reminders.

Clinical Trial Eligibility Criteria:

In order to participate you must meet the following criteria:

  • Are 12 years of age or older.
  • Have severe asthma as defined by commonly accepted guidelines.
  • Have uncontrolled asthma, or worsening asthma and attacks.
  • Are on a stable regimen of asthma medications.
  • Are not pregnant and not breastfeeding.
  • Are not taking part in other clinical trials.

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.

Study Details

Clinical Trial Investigator

James Moy, MD

Contact Information

Grace Li


RUSH Copley Medical Center

2000 Ogden Ave
Aurora, IL 60504

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