The Rush Inherited Susceptibility to Cancer Clinic provides counseling and testing (usually blood tests) for genetic mutations that can increase risk for cancer, such as BRCA1 and BRCA2 mutations. Genetic testing for cancer prediposition is available for certain types of breast cancer, colon cancer, leukemia, sarcoma, gynecologic cancers (e.g., ovarian cancer and endometrial cancer) and more.
Here are specific examples of diseases that the clinic addresses:
- Hereditary breast and ovarian cancer syndrome
- Lynch syndrome
- Li-Fraumeni syndrome
- Cowden syndrome
- Familial adenomatous polyposis (FAP) syndrome
Women with a personal history of breast cancer under the age of 50 and/or family history of breast or ovarian cancer may be candidates for genetic testing for breast cancer predisposition. Any woman with a personal history of ovarian cancer is a candidate for genetic testing for cancer predisposition.
Patients receive counseling before and after testing, which includes personalized information on prevention and early detection of cancer. For patients determined to be at high-risk for developing breast cancer, chemoprevention (medications given to reduce the risk of breast cancer) may be recommended. Psychological support is also available for individuals at high risk for cancer.