Study of the Optimal Evaluation of Cardiac Symptoms and Revascularization

Clinical Trial Title

PRECISE: Prospective randomized trial of the optimal evaluation of cardiac symptoms and revascularization.

Contact Information

Jennifer Fernandez

Clinical Trial Protocol Description:

The purpose of this study is to assess clinical outcomes, as well as physician decision making regarding noninvasive testing and invasive angiography in patients with stable symptoms suggestive of coronary artery disease (CAD). Patients will be assigned an evaluation strategy based on a pre-test risk assessment and randomized to either precision care or usual care. The precision care group will incorporate either cCTA with selective FFR-CT and guideline recommended care or symptom and risk factor management with no immediately planned testing. The usual care arm will be evaluated at their physician’s discretion.

Clinical Trial Eligibility Criteria:

In order to participate you must meet the following criteria:

  • Are 18 years old or older.
  • Have stable symptoms suggesting CAD
  • Have stable kidney function (creatinine clearance >45 mL/min).

You will be excluded from the study if any of the following criteria apply to you:

  • Have acute chest pain.
  • Have received any cardiovascular testing for CAD (stress test, angiogram, cCTA) within 1 year.

This is a partial list of inclusion and exclusion criteria. To inquire about your eligibility, please call the contact number provided.

Study Details

Clinical Trial Investigator

Dinesh K. Kalra, MD

Contact Information

Jennifer Fernandez

(312) 942-8144


Rush University Medical Center

1620 W Harrison St
Chicago, IL 60612

Get Directions

Clinical Trial FAQs

Find out if a clinical trial makes sense for you.

Learn more
Learn more