Radiation Therapy Treatment Study for Patients with Early-Stage Breast Cancer
A randomized phase III clinical trial evaluating post-mastectomy chest wall and regional nodal XRT and post-lumpectomy regional nodal XRT in patients with positive axillary nodes before neoadjuvant chemotherapy who convert to pathologically negative axillary nodes after neoadjuvant chemotherapy.
This randomized phase III trial studies standard or comprehensive radiation therapy in treating patients with early-stage breast cancer who have undergone surgery. Radiation therapy uses high-energy X-rays to kill tumor cells. It is not yet known whether comprehensive radiation therapy is more effective than standard radiation therapy in treating patients with breast cancer.
In order to participate you must meet the following criteria:
- Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
- Have clinically proven T1-3, N1 breast cancer at the time of diagnosis (before neoadjuvant therapy).
- Have completed a minimum of 8 weeks of standard neoadjuvant chemotherapy consisting of an anthracycline and/or taxane-based regimen.
This is a partial list of elgibility requirements.