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Predictors of Opioid Analgesic Responses Study

Clinical Trial Title: 
Predictors of opioid analgesic responses and common endogenous opioid mechanisms
Clinical Trial Protocol ID: 
09101401
Clinical Trial Investigator Name: 
John Burns, PhD
Clinical Trial Protocol Description: 

This study will focus on differences between both healthy people and people with lower back pain in how they respond to brief laboratory pain tasks while taking morphine, taking a substance that blocks the natural opioid-based pain systems in the body (naloxone), and while taking a placebo. You will receive compensation for your time and travel.

Clinical Trial Eligibility Criteria: 

In order to participate you must meet the following criteria:

  • Have had low back pain for at least six months or are healthy.
  • Are 18 to 55 years of age.

You will be excluded from the study if any of the following criteria apply to you:

  • Have cancer or rheumatoid arthritis.
  • Have other severe medical or psychiatric disorders.

This is a partial list of eligibility requirements. 

Clinical Trial Area: 
Spine and Back Disorders
Contact Phone: 
(312) 942-1435
Contact Name: 
Erik Schuster