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Predictors of Opioid Analgesic Responses Study

Clinical Trial Title: 
Predictors of opioid analgesic responses and common endogenous opioid mechanisms
Clinical Trial Protocol ID: 
Clinical Trial Investigator Name: 
John Burns, PhD
Clinical Trial Protocol Description: 

This study will focus on differences between both healthy people and people with lower back pain in how they respond to brief laboratory pain tasks while taking morphine, taking a substance that blocks the natural opioid-based pain systems in the body (naloxone), and while taking a placebo. You will receive compensation for your time and travel.

Clinical Trial Eligibility Criteria: 

In order to participate you must meet the following criteria:

  • Have had low back pain for at least six months or are healthy.
  • Are 18 to 55 years of age.

You will be excluded from the study if any of the following criteria apply to you:

  • Have cancer or rheumatoid arthritis.
  • Have other severe medical or psychiatric disorders.

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.

Clinical Trial Area: 
Spine and Back Disorders
Contact Phone: 
(312) 942-1435
Contact Name: 
Erik Schuster