Medication Treatment Study for Patients with Depression
This is a study to evaluate the safety and effectiveness of an investigational medication as an add-on treatment for adults with depression who are having an inadequate response to current antidepressant treatment. The study involves a screening period of 1-4 weeks, a treatment period of 6 weeks, and a follow-up period of 2 weeks. Participants will remain on the same antidepressant being taken at the time of study entry, with the investigational medication added on.
In order to participate you must meet the following criteria:
- Are between the ages 18-65 years old.
- Meet criteria for depression.
- Have been taking the same antidepressant for at least 6 weeks prior to study entry.
- Are willing and able to use birth control (if you are a female of childbearing potential).
You will be excluded from the study if any of the following criteria apply to you:
- Have certain other psychiatric or unstable medical illness, including bipolar disorder.
- Test positive for drugs of abuse or alcohol at the time of screening.
- Had your first episode of depression after age 60.
- Have a history of cataract, glaucoma, eye trauma, or intraocular surgery (including laser surgery).
- Are pregnant or breastfeeding.
This is a partial list of inclusion and exclusion criteria.