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Impact of Fever Prevention in Brain-Injured Patients Study

Clinical Trial Title: 
INTREPID: Impact of fever prevention in brain-injured patients.
Clinical Trial Protocol ID: 
Clinical Trial Investigator Name: 
George A. Lopez, MD
Clinical Trial Protocol Description: 

The purpose of this study is to determine whether proactive fever prevention using the Arctic Sun system will decrease the average fever burden and improve neurological outcomes in patients who have had a stroke. Nationwide, 1176 patients will be recruited for this study. At Rush University, we expect to recruit 24 patients. Treatment assignment will be assigned randomly between the Arctic Sun temperature management system and standard fever care.

Clinical Trial Eligibility Criteria: 

In order to participate you must meet the following criteria:

  • Are between the ages of 21 and 80 years old.
  • Are ischemic, ICH, or SAH (and meet disease-specific criteria).
  • Have historical mRS ≤ 2.

You will be excluded from the study if any of the following criteria apply to you:

  • Have a fever (≥ 38 C) prior to enrollment.
  • Have a skin condition or poor skin integrity/tissue perfusion.

This is a partial list of inclusion and exclusion criteria.

Clinical Trial Area: 
Stroke and Cerebrovascular Disease
Contact Phone: 
(312) 942-6731
Contact Name: 
Rebecca Holtz (Study Coordinator)