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Hypofractionated Radiation Therapy After Mastectomy in Patients With Stage IIa-IIIa Breast Cancer

Clinical Trial Title: 
Hypofractionated radiation therapy after mastectomy in preventing recurrence in patients with stage IIa-IIIa breast cancer.
Clinical Trial Protocol ID: 
Clinical Trial Investigator Name: 
Parul Barry, MD
Clinical Trial Protocol Description: 

This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells that remain after surgery and have fewer side effects.

Clinical Trial Eligibility Criteria: 

In order to participate you must meet the following criteria:

  • Have histologically confirmed invasive carcinoma of the breast of any of the following histologies: ductal, lobular, mammary, medullary, or tubular.
  • Have had no prior therapeutic radiation therapy to the chest, neck or axilla. Prior radioactive oral iodine is permitted.
  • Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0-1.

You will be excluded from the study if any of the following criteria apply to you:

  • Have clinical or radiological evidence of metastatic disease.

This is a partial list of inclusion and exclusion criteria.

Clinical Trial Area: 
Breast Cancer
Contact Email: 
Contact Phone: 
(312) CANCER-1
Contact Name: 
Rush Cancer Center Clinical Trials Office