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DAWN Trial

Clinical Trial Title: 
Prospective, randomized, blinded endpoint, control trial evaluating the Trevo Retrievers in the 6-24 hour after LKW period.
Clinical Trial Protocol ID: 
14050802
Clinical Trial Investigator Name: 
Michael Chen, MD
Clinical Trial Protocol Description: 

To evaluate the hypothesis that Trevo thrombectomy plus medical management leads to superior clinical outcomes at 90 days as compared to medical management alone in appropriately selected subjects experiencing an acute ischemic stroke when treatment is initiated within 6-24 hours after last seen well.

Number of visits: 2 additional visits post discharge

Expected duration of participation: 90 days

Tests performed: Labs, mRS, NIHSS, MRA, CTA, CTP (imaging at screen and 24hr post randomization),

Compensation: None

Clinical Trial Eligibility Criteria: 

In order to participate you must meet the following criteria:

  • Be at least 18 years of age.
  • Have more than 6 hours since LKW.
  • Have a failed/DQ for t-PA.
  • Have baseline NIHSS ≥10.
  • Have pre-procedure mRS ≤1.
  • Have additional imaging inclusion.

You will be excluded from the study if any of the following criteria apply to you:

  • Have severe head injury ≤90 days pre-procedure.
  • Have pre-existing neurological/psychiatric disease.
  • Have lab exclusion criteria, imaging criteria.

Enrollment: Late stroke patients either refered from outside institutions or in-house.

This is a partial list of inclusion and exclusion criteria.

Clinical Trial Area: 
Stroke and Cerebrovascular Disease
Contact Phone: 
(312) 942-1114
Contact Name: 
Bartosz Jacher