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Adjuvant Radiation Versus Chemoradiation in Cervical Cancer Previously Treated with Surgery

Clinical Trial Title: 
Randomized phase III clinical trial of adjuvant radiation versus chemoradiation in intermediate risk, stage I/IIA cervical cancer treated with initial radical hysterectomy and pelvic lymphadenectomy.
Clinical Trial Protocol ID: 
Clinical Trial Investigator Name: 
Jessica Zhou, MD
Clinical Trial Protocol Description: 

This trial studies radiation therapy with chemotherapy to see how well it works compared to radiation therapy alone in treating patients with stage I or stage II cervical cancer who previously underwent surgery. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation therapy together with chemotherapy is more effective than radiation therapy alone in treating patients with cervical cancer.

Clinical Trial Eligibility Criteria: 

In order to participate you must meet the following criteria:

  • Have stage I-IIA cervical cancer initially treated with a hysterectomy and lymph node removal.
  • Have had hysterectomy surgery between 3-8 weeks before enrollment in study. 

You will be excluded from the study if any of the following criteria apply to you:

  • Have had no previous radiation or chemotherapy for cervical cancer.

This is a partial list of inclusion and exclusion criteria.

Clinical Trial Area: 
Gynecologic Cancers
Contact Phone: 
(312) 942-0836
Contact Name: 
Adrianne Kajmowicz RN, BSN