Cold Agglutinin Titer

CERNER / EPIC MNEMONIC: COLD
CPT CODE: 86940
DAYS PERFORMED: Daily, 0800-1600
TURNAROUND TIME: 48 hours
SPECIAL INSTRUCTIONS: Arrangements should be made by calling the Blood Center at 25920.
CONTAINER TYPE: Plain red top tube (clot)
COLLECTION: Special Labeling Requirements: The initials of the person who collected the specimen and the date and time of collection MUST be noted on the specimen label.
SPECIMEN REQUIREMENTS: Blood (red cells and serum)
MINIMUM VOLUME: 7 mL
HANDLING INSTRUCTIONS:

Collect sample in prewarmed tube and deliver immediately to Blood Bank in warm water.  Do not put on ice!

REFERENCE RANGE: Screen: negative; titer <32
TEST SYNONYM(S):Cold Hemagglutinin Titer

Cord Blood Screening

CERNER / EPIC MNEMONIC: CORD
POE DESCRIPTION: CORD BLOOD ABO AND DAT; CORD ABO, RH, DAT (COOMBS)
CPT CODE: 86880; 86900; 86901
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: 1 hour
SPECIAL INSTRUCTIONS: Indicate cord blood, baby`s hospital number, baby`s sex, time of birth, and mother`s hospital number.
CONTAINER TYPE:

Pink top tube

COLLECTION: Special Labeling Requirements: The initials of the person who collected the specimen and the date and time of collection MUST be noted on the specimen label.
SPECIMEN REQUIREMENTS: Blood
MINIMUM VOLUME: 2 mL
TEST SYNONYM(S):Cord Blood Work-up

Cord Clot

SPECIAL INSTRUCTIONS: Cord blood - to hold in Blood Bank order Cord Clot. If testing is indicated, the physician should phone the Blood Center at ext 2-5920 and order Cord Blood Screening. See Cord Blood Screening for sample requirements.
CONTAINER TYPE:

Pink top tube

COLLECTION: Special Labeling Requirements: The initials of the person who collected the specimen and the date and time of collection MUST be noted on the specimen label.

Cryoprecipitate, Transfusion

CERNER / EPIC MNEMONIC: (not orderable on LIS)
POE DESCRIPTION:

Pooled Cryo (1 pool = 4 donors)

DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: 30 minutes
SPECIAL INSTRUCTIONS: Cryoprecipitate must be infused within 4 hours from time of thaw. Order by quantity of fibrinogen needed or specify number of 'bags' (150-250 mg per bag)
CONTAINER TYPE:

Pink top tube

SPECIMEN REQUIREMENTS: Blood
MINIMUM VOLUME: 7 mL
HANDLING INSTRUCTIONS: Store pooled cryoprecipitate units at room temperature.
REFERENCE RANGE: Each bag contains at least 150 mg fibrinogen

C-Reactive Protein

CERNER / EPIC MNEMONIC: CRP
CPT CODE: 86140
DAYS PERFORMED:

Specimen accepted daily, 24 hours

TURNAROUND TIME:

Routine: 8 hours, STAT: 1 hour

CONTAINER TYPE:

SST tube or  Red top tube

SPECIMEN REQUIREMENTS: Blood (serum)
MINIMUM VOLUME: 0.4 mL blood (0.2 mL serum)
HANDLING INSTRUCTIONS:

 

REFERENCE RANGE:

< 8.0 mg/L

LAST UPDATED:

6-6-2013

TEST SYNONYM(S):Acute Phase Protein; CRP

C3 Complement, Serum

CERNER / EPIC MNEMONIC: C3
POE DESCRIPTION: C3 COMPLEMENT
DAYS PERFORMED:

Daily, 24 hours

TURNAROUND TIME:

8 hours

CONTAINER TYPE:

Red top tube - 4 mL or SST tube

SPECIMEN REQUIREMENTS:

4 mL blood (2.0 mL serum)

REJECTION CRITERIA:

Gross Hemolysis, Grossly lipemic

MINIMUM VOLUME: 1 mL blood (0.5 mL serum)
METHODOLOGY:

Immunoturbidimetric

TEST SYNONYM(S):Complement B1C/B1A; Complement C3

C4 Complement, Serum

CERNER / EPIC MNEMONIC: C4
POE DESCRIPTION: C4 COMPLEMENT
DAYS PERFORMED:

Daily, 24 hours

TURNAROUND TIME:

8 hours

CONTAINER TYPE:

Red top tube - 4 mL or SST tube

SPECIMEN REQUIREMENTS:

4.0 mL blood (2.0 mL serum)

REJECTION CRITERIA:

Gross Hemolysis, Grossly lipemic

MINIMUM VOLUME: 1 mL blood (0.5 mL serum)
METHODOLOGY:

Immunoturbidimetric

TEST SYNONYM(S):Complement C4

CA 125

CERNER / EPIC MNEMONIC: CA125
POE DESCRIPTION: CA 125; CA125
CPT CODE: 86304
DAYS PERFORMED: Daily, First shift
TURNAROUND TIME:

8-24 hours

CONTAINER TYPE:

Red top tube - 4 mL or SST tube

SPECIMEN REQUIREMENTS:

4 mL blood (2 mL serum)

REJECTION CRITERIA:

Gross hemolysis

MINIMUM VOLUME: 1.0 mL blood (0.3 mL serum)
REFERENCE RANGE:

Male / Female: (0 – adult) 0 – 31 U/ML

METHODOLOGY:

Chemiluminescent Microparticle Immunoassay (CMIA)

LAST UPDATED:

11-11-2013

CA 15-3

CERNER / EPIC MNEMONIC: CA 15-3
POE DESCRIPTION: CA 15-3
CPT CODE: 86316
DAYS PERFORMED: Daily, First shift
TURNAROUND TIME:

8-24 hours

CONTAINER TYPE:

Red top tube - 4 mL or SST tube

SPECIMEN REQUIREMENTS:

4 mL b lood (2.0 mL serum)

REJECTION CRITERIA:

Gross hemolysis

MINIMUM VOLUME: 1.0 mL blood (0.3 mL serum)
METHODOLOGY:

Chemiluminescent Microparticle Immunoassay (CMIA)

TEST SYNONYM(S):Breast Antigens 115D8/DF3

Calcium, Ionized

CERNER / EPIC MNEMONIC: ION CA
POE DESCRIPTION: CALCIUM IONIZED; IONIZED CALCIUM
CPT CODE: 82330
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 15 minutes
SPECIAL INSTRUCTIONS: Deliver specimen immediately to the lab on ice. This test cannot be added onto an existing sample.
CONTAINER TYPE: Heparinized syringe or 4 mL Lithium Heparin green top tube
SPECIMEN REQUIREMENTS: Heparinized whole blood
REJECTION CRITERIA: Clotted syringe, needle attached to the syringe, and air bubbles in the sample.
MINIMUM VOLUME: 1 mL whole blood
HANDLING INSTRUCTIONS: Deliver to the laboratory immediately. Keep specimen on ice.
TEST SYNONYM(S):Ion Ca

Calcium, Fluid

CERNER / EPIC MNEMONIC: F/CA
POE DESCRIPTION: FLUID CALCIUM
CPT CODE: 82310
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 1 hour
SPECIAL INSTRUCTIONS:

Must specify fluid type on the requisition.

CONTAINER TYPE:

Red top tube - 10 mLRed top tube - 4 mLSterile 80 mL specimen container

SPECIMEN REQUIREMENTS: Body fluid
MINIMUM VOLUME: 0.2 mL
REFERENCE RANGE: None established

Calcium, Quantitative, Urine

CERNER / EPIC MNEMONIC: RU/CA (random urine); U/CA (24-hour urine)
POE DESCRIPTION:

Urine Calcium Random; Urine Calcium Timed

CPT CODE: Random = 82340; Timed 82340, 81050
TEST INFORMATION: Results are reported as milligrams of calcium per total volume of urine submitted. Normal range is based on 24-hour collection.
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 8 hours
SPECIAL INSTRUCTIONS:

For timed urine collection, instruct the patient to void at the beginning of the collection period and discard the specimen.  Then collect all urine including the final specimen voided at the end of the collection period.  Containers must be labeled with patient's full name, room number, date and time collection started, and date and time collection finished.

CONTAINER TYPE:

Random Sterile 80 mL specimen container, Timed 24 hour urine container (Bottle #1) with no preservative or 24 hour urine container (Bottle #4) with 10 mL 6 N HCl

SPECIMEN REQUIREMENTS:

Random or 24-hour urine

MINIMUM VOLUME:

Random urine: 1 mL

Timed Urine: Submit entire urine collection to the laboratory.

HANDLING INSTRUCTIONS: Keep refrigerated during collection.
REFERENCE RANGE:

Random urine: None established

Timed urine: varies with diet; adult: 50-300 mg/24 hours on average diet.

TEST SYNONYM(S):Urine Calcium

Calcium, Serum

CERNER / EPIC MNEMONIC: CA
POE DESCRIPTION: CALCIUM; CA
CPT CODE: 82310
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Routine: 8 hours; stat: 1 hour
CONTAINER TYPE:

SSTTM tube

SPECIMEN REQUIREMENTS: Blood (serum)
MINIMUM VOLUME: 0.4 mL blood (0.2 mL serum)
REFERENCE RANGE:

1 day - 1 month:  7.3 - 11.9 mg/dL

1 month - adult:   8.7 - 10.7 mg/dL

CRITICAL VALUES: < 5.0; > 13.0
LAST UPDATED:

3-25-2013

TEST SYNONYM(S):Ca



Cannabinoids, Qualitative, Urine

CERNER / EPIC MNEMONIC: U/DS
POE DESCRIPTION: URINE DRUG SCREEN; U/DS
CPT CODE: 80100 (x7)
TEST INFORMATION: Not orderable as separate test. Order Drug Screen, Urine
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Routine: 4 hours; stat: 1 hour
SPECIAL INSTRUCTIONS: Do not use for medicolegal purposes. For medicolegal purposes, specimens should be collected using chain-of-custody precautions and screening results should be confirmed using gas chromatography/mass spectrometry. Chain-of-custody and confirmation are not part of the urine drug screen and are not provided by this laboratory.
CONTAINER TYPE: Sterile 80 mL specimen container
SPECIMEN REQUIREMENTS: 1.0 mL random urine
MINIMUM VOLUME: 0.5 mL random urine
REFERENCE RANGE: None detected
METHODOLOGY:

FPIA (Fluorescence Polarization Immuoassay)

TEST SYNONYM(S):Cannabis; Marijuana; THC

Carbamazepine, Serum

CERNER / EPIC MNEMONIC: CARB
POE DESCRIPTION: CARBAMAZEPINE; TEGRETOL
CPT CODE: 80156
TEST INFORMATION: Optimal sampling time is at trough, just before the next dose.
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Routine: 4 hours; stat: 1 hour
CONTAINER TYPE: Red top tube - 4 mL
SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME: 1.0 mL blood (0.3 mL serum)
METHODOLOGY:

Enzyme Immunoassay

CRITICAL VALUES:

>18 ug/mL

TEST SYNONYM(S):Tegretol.

Carbon Dioxide, Fluid

CERNER / EPIC MNEMONIC: F/CO2
POE DESCRIPTION: FLUID TOTAL CARBON DIOXIDE
CPT CODE: 82374
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 1 hour
SPECIAL INSTRUCTIONS:

Must specify fluid type on the requisition.

CONTAINER TYPE:

Red top tube - 10 mLRed top tube - 4 mLSterile 80 mL specimen container

SPECIMEN REQUIREMENTS: Body fluid
MINIMUM VOLUME: 0.2 mL
REFERENCE RANGE: None established
TEST SYNONYM(S):Fluid Carbon Dioxide

Carbon Dioxide, Total, Serum

CERNER / EPIC MNEMONIC: CO2
POE DESCRIPTION: CARBON DIOXIDE; CO2
CPT CODE: 82374
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Routine: 8 hours; stat: 1 hour
CONTAINER TYPE:

SSTTM tube

SPECIMEN REQUIREMENTS: Blood (serum)
MINIMUM VOLUME: 0.4 mL blood (0.2 mL serum)
REFERENCE RANGE: 0-1 year: 13-22 mmol/L; 1-15 years: 20-28 mmol/L; 15 years to adult: 22-29 mmol/L
CRITICAL VALUES:

≤ 10 mmol/L

TEST SYNONYM(S):CO2; Total CO2

Carbon Dioxide, Total, Urine

CERNER / EPIC MNEMONIC: RU/CO2
POE DESCRIPTION:

Urine CO2 Random

CPT CODE: 82374
TEST INFORMATION: Test is not performed on urines with pH <6.
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 8 hours
CONTAINER TYPE: Sterile 80 mL specimen container
SPECIMEN REQUIREMENTS: Random urine
MINIMUM VOLUME:

1 mL

REFERENCE RANGE: None established
TEST SYNONYM(S):CO2, Total, Urine; HCO3, Urine; Bicarbonate, Urine; Urine Carbon Dioxide

Carboxyhemoglobin, Blood

CERNER / EPIC MNEMONIC: CARB/HB
POE DESCRIPTION: CARBOXYHEMOGLOBIN; CARB/HB
CPT CODE: 82375
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Stat: 15 minutes
SPECIAL INSTRUCTIONS: Keep blood on ice if oxygen saturation is to be measured. If only carboxyhemoglobin is ordered, ice is not necessary.
CONTAINER TYPE: Heparinized syringe or green top tube (heparin)
SPECIMEN REQUIREMENTS: Blood, arterial or venous
REJECTION CRITERIA: Clotted syringe, needle attached to the syringe, and air bubbles in the sample.
MINIMUM VOLUME: 0.3 mL
REFERENCE RANGE: Nonsmoker: 0% to 5%
TEST SYNONYM(S):Carbon Monoxide; CO

Carcinoembryonic Antigen

CERNER / EPIC MNEMONIC: CEA
POE DESCRIPTION: CARCINOEMBRYONIC; CEA
CPT CODE: 82378
DAYS PERFORMED: Daily, First shift
TURNAROUND TIME:

8-24 hours

CONTAINER TYPE:

Red top tube - 4 mL or SST tube

SPECIMEN REQUIREMENTS:

4.0 mL blood (2.0 mL serum)

REJECTION CRITERIA:

Any hemolysis of sample

MINIMUM VOLUME: 1.0 mL blood (0.3 mL serum)
TEST SYNONYM(S):Carcinoembryonic Antigen; CEA

Cerebrospinal Fluid, Cell Count and Differential

CERNER / EPIC MNEMONIC: C/C-D
POE DESCRIPTION: CSF CELL COUNT DIFF
CPT CODE: 89051
DAYS PERFORMED: Daily, 24 hours; available stat
TURNAROUND TIME: 8 hours. Cell count available in 1 hour.
SPECIAL INSTRUCTIONS: Specimen should be delivered by hand to the laboratory within 1 hour of aspiration.
CONTAINER TYPE:

Sterile test tube from lumbar puncture kit, CSF collection tube or Lavender top 3 ml-draw tube. Do Not use red top plastic tube.

SPECIMEN REQUIREMENTS:

Cerebrospinal fluid, at least 1 mL in a sterile CSF or lavender top tube.

MINIMUM VOLUME: 1 mL
HANDLING INSTRUCTIONS: Do not store; place in the hands of laboratory personnel.
REFERENCE RANGE: 0-10 cells/mm³, all lymphocytes and monocytes, 0 red blood cells
LAST UPDATED:

1-28-2013

TEST SYNONYM(S):CSF, Cell Count; LP; Lumbar Puncture; Spinal Fluid Cell Count; Spinal Tap

Ceruloplasmin

CERNER / EPIC MNEMONIC: CERULO
POE DESCRIPTION: CERULOPLASMIN
CPT CODE: 82390
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

SSTTM or Red top tube

SPECIMEN REQUIREMENTS: 2.0 mL Blood (1.0 mL serum)
MINIMUM VOLUME: 1 mL blood (0.5 mL serum)
HANDLING INSTRUCTIONS: Separate serum and freeze.
REFERENCE RANGE:

See Specialty Labs - Search Test Code 1516

METHODOLOGY:

Nephelometry

TEST SYNONYM(S):CP

Chloride, Blood

CERNER / EPIC MNEMONIC: BG/CL; CL
POE DESCRIPTION: CHLORIDE; CL
CPT CODE: 82435
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Stat: 1 hour; blood gas: 15 min
CONTAINER TYPE:

SSTTM tube or heparinized syringe

SPECIMEN REQUIREMENTS: Blood (serum, plasma)
REJECTION CRITERIA: Clotted syringe, needle attached to the syringe, and air bubbles in the sample.
MINIMUM VOLUME: 0.4 mL blood, 0. 2 mL serum, 0.3 mL whole blood
REFERENCE RANGE: Newborns: 0-1 month: 91-118 mmol/L; children and adults: 99-108 mmol/L
TEST SYNONYM(S):Cl

Chloride, Cerebrospinal Fluid

CERNER / EPIC MNEMONIC: C/CL
POE DESCRIPTION: CSF CHLORIDE
CPT CODE: 82438
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME:

1 hour

CONTAINER TYPE:

CSF collection tubesRed top tube - 10 mLRed top tube - 4 mL

SPECIMEN REQUIREMENTS:

Cerebrospinal fluid

MINIMUM VOLUME: 0.2 mL
TEST SYNONYM(S):CSF Chloride

Chloride, Quantitative, Urine

CERNER / EPIC MNEMONIC: RU/CL (random urine); U/CL ((24-hour urine)
POE DESCRIPTION:

Urine Chloride Random; Urine Chloride Timed

CPT CODE: Random = 82436, Timed = 82436, 81050
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME:

Stat: 1 hour (random urine only); routine 8 hours

SPECIAL INSTRUCTIONS: For timed urine collection, instruct the patient to void at the beginning of the collection period and discard the specimen. Then collect all urine including the final specimen voided at the end of the collection period. Containers must be labeled with patient`s full name, room number, date and time collection started, and date and time collection finished.
CONTAINER TYPE:

Random Sterile 80 mL specimen container, Timed 24 hour urine container (Bottle #1) with no preservative

SPECIMEN REQUIREMENTS:

Random or 24-hour urine

MINIMUM VOLUME:

Random urine: 1 mL

Timed urine: Submit entire urine collection to the laboratory.

HANDLING INSTRUCTIONS: Keep refrigerated during collection.
REFERENCE RANGE: Random urine: None established; Timed urine: 15-250 mmol/24 hours, varies with diet
TEST SYNONYM(S):Urine Cl; Cl, Urine; Urine Chloride

Cholesterol, Serum

CERNER / EPIC MNEMONIC: CHOL
POE DESCRIPTION: CHOLESTEROL; CHOL
CPT CODE: 82465; 82465
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Routine: 8 hours; stat: 1 hour
CONTAINER TYPE:

SSTTM tube

SPECIMEN REQUIREMENTS: Blood (serum)
MINIMUM VOLUME: 2 mL blood (0.4 mL serum)
REFERENCE RANGE:

Normal Ranges

                                      Male (mg/dL)                 Female (mg/dL)

Recommended:                   <200                                 <200

Moderate Risk:                200 - 239                            200 - 239

High Risk:                            >239                                    >239

LAST UPDATED:

3-25-2013

Cholesterol, Total, Fluid

CERNER / EPIC MNEMONIC: F/CHOL
POE DESCRIPTION: FLUID CHOLESTEROL TOTAL
CPT CODE: 82465
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 1 hour
SPECIAL INSTRUCTIONS:

Must specify fluid type on the requisition.

CONTAINER TYPE:

Red top tube - 10 mLRed top tube - 4 mLSterile 80 mL specimen container

SPECIMEN REQUIREMENTS: Body fluid
MINIMUM VOLUME: 0.2 mL fluid
REFERENCE RANGE: None established
TEST SYNONYM(S):Fluid Cholesterol, total

Circulating Anticoagulant

CERNER / EPIC MNEMONIC: LUPUS PL
POE DESCRIPTION: LUPUS ANTICOAGULANT ANTIBODIES; LUPUS COAG
CPT CODE:

85613, 85597

TEST INFORMATION:

Includes Hexagonal Phase and DRVVT and reflex to confirmation.

DAYS PERFORMED: Monday, Wednesday, and Friday
TURNAROUND TIME: 48-72 hours
SPECIAL INSTRUCTIONS:

This test cannot be added onto an existing sample.

CONTAINER TYPE:

Blue top (citrate) tube

COLLECTION:

See Section - " Specimen Collection Guidelines" - Coagulation Specimens

SPECIMEN REQUIREMENTS: Blood, 4.5 mL tube
REJECTION CRITERIA: Specimen hemolyzed; Hct >65%
MINIMUM VOLUME: 4.0 mL blood (1.5 mL plasma)
HANDLING INSTRUCTIONS: Transport the specimen to the laboratory as soon as possible. Specimen MUST be received within 4 hours after collection. Specimen must be centrifuged for 30 minutes at 3000 rpm to assure platelet poor plasma.
REFERENCE RANGE: Lupus anticoagulant not detected.
REFERRAL LABORATORY:

See Specialty Labs - Rush Custom Panel #P6126M

TEST SYNONYM(S):Acquired Anticoagulant; Lupus Anticoagulant; Phospholipid Inhibitor

Co-oximetry Panel, Blood

CERNER / EPIC MNEMONIC: COOX PANEL
POE DESCRIPTION: COOXIMETRY PANEL
CPT CODE: 82375; 82810; 83050
TEST INFORMATION: Test includes measured O2 saturation, carboxyhemaglobin, methemaglobin, total hemoglobin, and deoxygenated hemoglobin
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 15 minutes
SPECIAL INSTRUCTIONS: Deliver specimen immediately to the lab on ice.
CONTAINER TYPE: Heparinized syringe
SPECIMEN REQUIREMENTS: Blood, heparinized syringe
REJECTION CRITERIA: Clotted syringe, needle attached to the syringe, and air bubbles in the sample.
MINIMUM VOLUME: 0.3 mL
REFERENCE RANGE: See Table

Cocaine Metabolite, Qualitative, Urine

CERNER / EPIC MNEMONIC: U/DS
POE DESCRIPTION: URINE DRUG SCREEN; U/DS
CPT CODE: 80100 (x7)
TEST INFORMATION: Not orderable as separate test. Order Drug Screen, Urine
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Routine: 4 hours; stat: 1 hour
SPECIAL INSTRUCTIONS: Do not use for medicolegal purposes. For medicolegal purposes, specimens should be collected using chain-of-custody precautions and screening results should be confirmed using gas chromatography/mass spectrometry. Chain-of-custody and confirmation are not part of the urine drug screen and are not provided by this laboratory.
CONTAINER TYPE: Sterile 80 mL specimen container
SPECIMEN REQUIREMENTS: 1.0 mL random urine
MINIMUM VOLUME: 0.5 mL random urine
REFERENCE RANGE: None detected
METHODOLOGY:

FPIA (Fluorescence Polarization Immuoassay)

TEST SYNONYM(S):Cocaine Metabolite; Cocaine, Qualitative, Urine; Cocaine Screen

Complete Blood Count with Differential

CERNER / EPIC MNEMONIC: CBC/D
POE DESCRIPTION: COMPLETE BLOOD COUNT WITH DIFFERENTIAL

CPT CODE: 85025
TEST INFORMATION: Test includes: CBC, differential
DAYS PERFORMED: Daily, 24 hours; available stat
TURNAROUND TIME: 8 hours; stat Hematology Panel; 1 hour
CONTAINER TYPE:

Lavender top (K2 EDTA) tube

SPECIMEN REQUIREMENTS: Blood
REJECTION CRITERIA: - Clotted or hemolyzed specimen

- CBC, >24 hours old;

- Differential, >12 hours old

MINIMUM VOLUME: 1.5 mL venous, 250 µL capillary whole blood
HANDLING INSTRUCTIONS: Specimen should be sent to the laboratory as soon as possible.
REFERENCE RANGE: See Table 1; See Table 2
REFERENCE CHART:

Microcytosis evaluation

LAST UPDATED:

11-21-2013

TEST SYNONYM(S):Blood Count with differential

Comprehensive Metabolic Panel, Serum

CERNER / EPIC MNEMONIC: CMP
POE DESCRIPTION: COMPREHENSIVE METABOLIC PANEL; CMP
CPT CODE: 80053
TEST INFORMATION: Test includes albumin, total bilirubin, calcium, carbon dioxide, chloride, creatinine, glucose, alkaline phosphatase, potassium, total protein, sodium, SGOT(AST), SGPT(ALT) and urea nitrogen
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Routine: 8 hours; stat: 1 hour
CONTAINER TYPE:

SSTTM tube or Microtainer (Lithium heparin SST) for neonates

SPECIMEN REQUIREMENTS: Blood (serum), plasma
MINIMUM VOLUME: 4 mL blood (2 mL serum)
REFERENCE RANGE: Normal Ranges for Common Laboratory Tests  
CRITICAL VALUES: Sodium:  ≤ 120 mmol/L,  ≥ 160 mmol/L; potassium:  < 2.5 mmol/L, > 6.5 mmol/L; calcium < 5 mg/dL, > 13 mg/dL; glucose:  0-18 years, < 30 mg/dL; total bilirubin: 0-7 days, ≥ 18 mg/dL, 7 days to adult, ≥ 25 mg/dL
TEST SYNONYM(S):CMP

Cortisol, Serum

CERNER / EPIC MNEMONIC: CORTISOL
POE DESCRIPTION: CORTISOL SERUM
CPT CODE: 82533
DAYS PERFORMED: Daily
TURNAROUND TIME:

8 hours

CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS: Blood (serum)
MINIMUM VOLUME:

1 mL blood (0.5 mL serum)

REFERENCE RANGE: Adults: 8-10 a.m., 3.7-19.4 mcg/dL; 4-6 p.m., 2.9-17.3 mcg/dL ACTH Stimulation: > twice reference a.m. level Post-Metyrapone Suppression: <4.0 mcg/dL(a.m.) Post-Dexamethasone Suppression: <4.0 mcg/dl (a.m.)/>4.0 mcg/dL with endogenous depression (at 16-23 hours after dexamethasone administration)
TEST SYNONYM(S):Compound F; Hydrocortisone

Cortrosyn. Stimulation Test

CERNER / EPIC MNEMONIC: CORTISOL
POE DESCRIPTION: CORTISOL SERUM
CPT CODE: 82533
DAYS PERFORMED:

Daily

TURNAROUND TIME: 1-3 days
SPECIAL INSTRUCTIONS: Specify on requisition baseline level or level 1 hour after Cortrosyn® stimulation. This test can be performed on outpatients but the ordering physician must be available to inject the Cortrosyn®.
CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS: Blood (serum)
REJECTION CRITERIA: Heparinized plasma
MINIMUM VOLUME: 0.5 mL blood (0.2 mL serum)
REFERENCE RANGE: Baseline cortisol at least 5 µg/dL; increase in cortisol at least 7 µg/dL; peak (1-hour) cortisol at least 18 µg/dL
TEST SYNONYM(S):Cortrosyn; Cortisol Stimulation Test

Creatine Kinase, Serum, Cerebrospinal Fluid

CERNER / EPIC MNEMONIC: CK; C/CK
POE DESCRIPTION: CREATINE PHOSPHOKINASE; TOTAL CK; CPK; CK
CPT CODE: 82550
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Routine: 8 hours; stat: 1 hour; CSF: 1 hour
CONTAINER TYPE:

SSTTM tube or CSF collection tube

SPECIMEN REQUIREMENTS: Blood (serum), cerebrospinal fluid
MINIMUM VOLUME: 0.4 mL blood (0.2 mL serum), 0.2 mL CSF
REFERENCE RANGE: Serum: 10-205 units/L; CSF: none established, must be interpreted with clinical findings
TEST SYNONYM(S):CK; CPK

Creatinine Clearance

CERNER / EPIC MNEMONIC: U/CRCL
POE DESCRIPTION: URINE CREATININE CLEARANCE
CPT CODE: 82575, 81050
TEST INFORMATION: For optimal results, the patient should avoid meat, tea, coffee, or drugs on the day of the test.
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 8 hours
SPECIAL INSTRUCTIONS: Blood creatinine should be ordered and sent to the laboratory during urine collection. Both blood and urine creatinine measurements are necessary to calculate creatinine clearance. If a corrected clearance is requested, the patient`s height and weight must be written on the requisition. For timed urine collection, instruct the patient to void at the beginning of the collection period and discard the specimen. Collect all urine including the final specimen voided at the end of the collection period. Containers must be labeled with patient`s full name, room number, date and time collection started, and date and time collection finished.
CONTAINER TYPE:

SSTTM tube, 24 hour urine container (Bottle #1) with no preservative

SPECIMEN REQUIREMENTS: Blood (serum), 24-hour urine collection
MINIMUM VOLUME: 4 mL blood (2 mL serum); submit entire urine collection to the laboratory.
HANDLING INSTRUCTIONS: Refrigerate urine during collection.
REFERENCE RANGE:

Male: (8 -15yrs) 98 – 150 ml/min

              (15- adult) 85 -125 ml/min

Female: (8-15yrs) 95-122 ml/min

              (15 – adult) 75 -115 ml/mn

LAST UPDATED:

11-11-2013

TEST SYNONYM(S):Clearance, Creatinine; CrCl; Creat Clearance; Creatinine Clearance, Endogenous

Creatinine, Fluid

CERNER / EPIC MNEMONIC: F/CREAT
POE DESCRIPTION: FLUID CREATINE
CPT CODE: 82570
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: 1 hour
SPECIAL INSTRUCTIONS:

Must specify fluid type on the requisition.

CONTAINER TYPE:

Red top tube - 10 mLRed top tube - 4 mLSterile 80 mL specimen container

SPECIMEN REQUIREMENTS: Body Fluid
MINIMUM VOLUME: 0.2 mL
REFERENCE RANGE: None established
TEST SYNONYM(S):Fluid Creatinine

Creatinine, Quantitative, Urine

CERNER / EPIC MNEMONIC: RU/CREAT (random urine); U/CREAT (24-hour urine)
POE DESCRIPTION:

Urine Creatinine Random; Urine Creatine Timed

CPT CODE:

Random = 82570, Timed = 82570, 81050

TEST INFORMATION: Results are reported as mg of creatinine per total volume of urine submitted. Normal range is based on 24-hour collection.
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Stat: 1 hour (random urine only); Timed urine: 8 hours
SPECIAL INSTRUCTIONS: For timed urine collection, instruct the patient to void at the beginning of the collection period and discard the specimen. Then collect all urine including the final specimen voided at the end of the collection period. Containers must be labeled with patient`s full name, room number, date and time collection started, and date and time collection finished.
CONTAINER TYPE:

Random Sterile 80 ml specimen container, Timed 24 hour urine container (Bottle #1) with no preservative

SPECIMEN REQUIREMENTS:  Random urine or 24-hour urine
MINIMUM VOLUME: Random urine: 1 mL; Timed urine: Submit entire urine collection to the laboratory.
HANDLING INSTRUCTIONS: Refrigerate during collection.
REFERENCE RANGE:

Random Urine:  None established

Timed Urine:      Male: 1,000 – 2,000 MG/TV

                           Female: 800 – 1800 MG/TV

LAST UPDATED:

11-12-2013

TEST SYNONYM(S):Total Creatinine, Urine; Urine Creatinine

Creatinine, Serum

CERNER / EPIC MNEMONIC: CREAT
POE DESCRIPTION: CREATINE; CREAT
CPT CODE: 82565
DAYS PERFORMED: Specimen accepted daily, 24 hours
TURNAROUND TIME: Routine: 8 hours; stat: 1 hour
CONTAINER TYPE:

SSTTM tube

SPECIMEN REQUIREMENTS: Blood (serum)
MINIMUM VOLUME: 0.4 blood (0.2 serum)
REFERENCE RANGE:

male         0.75-1.20

female      0.65-1.00 

Crystal Analysis, Synovial Fluid

CERNER / EPIC MNEMONIC: F/CRYS ANL
POE DESCRIPTION: CRYSTAL ANALYSIS SYNOVIAL FL; FL CRYSTAL ANALYSIS SYNOVIAL; SYNOVIAL CRYSTAL ANALYSIS
CPT CODE: 89060
DAYS PERFORMED: Daily, 0800-2300
TURNAROUND TIME: 8 hours
CONTAINER TYPE: Lavender top (EDTA) tube
SPECIMEN REQUIREMENTS: Synovial fluid
MINIMUM VOLUME: 1 mL
HANDLING INSTRUCTIONS:

Specimen must be transported promptly to the laboratory.  Refrigerate if transport is delayed.

REFERENCE RANGE: Negative for crystals
LAST UPDATED:

4-13-2012

TEST SYNONYM(S):Pseudogout Crystals; Synovial Fluid Crystals; Uric Acid Crystals; Gout Crystals

Cyclosporine, Whole Blood

CERNER / EPIC MNEMONIC: CSA
POE DESCRIPTION: CYCLOSPORIN, CYCLOSPORIN-FPIA
CPT CODE: 80158
DAYS PERFORMED: Test performed Monday-Sunday
TURNAROUND TIME: Up to 18 hours
SPECIAL INSTRUCTIONS: Time of draw must be indicated on requisition.
CONTAINER TYPE: Lavender top (K2 EDTA) tube - 3 mLLavender top (K2 EDTA) tube - 6 mLMicrotainer (K2 EDTA)Pink top (K2 EDTA) tube - 6 mL
SPECIMEN REQUIREMENTS:

1.0 mL EDTA whole blood

MINIMUM VOLUME: 0.5 mL EDTA whole blood
REFERENCE RANGE:

The effective therapeutic range for Cyclosporine is based upon clinical evaluation of the individual patient, because optimal levels depend upon multiple factors, including patient variation, type of transplant, time post-transplant, co-administration of other immunosuppressants, and method used.

TEST SYNONYM(S):Neoral; CSA; Cyclosporine A; CSA mono

Culture for Acanthamoeba/Naegleria/Balmuthia/Pathogenic Free Living Amoeba

CERNER / EPIC MNEMONIC: MICRO REF
POE DESCRIPTION: MICROBIOLOGY REFERRAL
CPT CODE:

87081

TEST INFORMATION:

Test includes culture for Acanthamoeba/Naegleria/Balmuthia/Pathogenic Free Living Amoeba species only.

DAYS PERFORMED:

Mon-Fri, 0800-1500

TURNAROUND TIME: Preliminary reports are available after 48 hours or when ameba are detected. Cultures will be finalized after 1 week.
SPECIAL INSTRUCTIONS: The Clinical Microbiology Laboratory MUST be contacted at (312) 942-5452, prior to submission of the specimen. The specific anatomic site of the specimen MUST be specified on the order or the requisition.
CONTAINER TYPE: Sealed, sterile container
COLLECTION: The specimens of choice are cerebrospinal fluid and ocular specimens. Specimens are to be collected from a site prepared utilizing aseptic technique. Swabs must NOT be used. Contamination with normal flora from skin or other body sources MUST be avoided since colonizing bacteria not involved in the infectious process may be introduced into the sample.
SPECIMEN REQUIREMENTS: Cerebrospinal fluid, corneal biopsy, corneal scraping, contact lens cleaning solution/drops
REJECTION CRITERIA: Specimen received in a fixative.
MINIMUM VOLUME: 0.5 mL or piece of tissue
HANDLING INSTRUCTIONS: Specimen MUST be transported directly to the Clinical Microbiology Laboratory, 1133 Jelke SC as soon as possible. When transportation is delayed, leave at room temperature. Do NOT refrigerate.
REFERENCE RANGE: No parasites found
METHODOLOGY: Culture in non-nutrient agar with Esherichia coli.
REFERRAL LABORATORY:

Commercial

ADDITIONAL INFORMATION: Naegleria species cause primary amebic meningoencephalitis. Acanthamoeba species cause disseminated infection in severely immunocompromised individuals, chronic granulomatous amebic encephalitis and/or sight-threatening ocular infections.
LAST UPDATED:

5-20-2014

TEST SYNONYM(S):Naegleria species; Free Living Amebas

Cardiolipin IgG/IgM Antibodies

CERNER / EPIC MNEMONIC: CARDIOLIP
POE DESCRIPTION: CARDIOLIPIN AB
CPT CODE: 86147-90 x2
TEST INFORMATION: Test includes both qualitative and quantitative IgG and IgM anticardiolipin antibodies.
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

SST TM tube or red top Vacutainer tube®

SPECIMEN REQUIREMENTS:

2 mL blood (1.0 mL serum)

MINIMUM VOLUME: 1 mL blood (0.5 mL serum)
REFERENCE RANGE: See Quest Diagnostics - Search Test Code 36333
REFERENCE CHART: page to be defined
TEST SYNONYM(S):Anticardiolipin antibodies

Catheter Tip Culture

CERNER / EPIC MNEMONIC: C AER
POE DESCRIPTION: CU CATHETER TIP; C CATHETER TIP CULTURE
CPT CODE: 87071
TEST INFORMATION: The test includes a semi-quantitative culture via the Maki method; isolation and identification of microorganisms with greater than 15 colonies, and susceptibility testing, if appropriate. Other isolated organisms (i.e. yeast, mycobacteria, etc.) may be referred for identification and/or susceptibility testing if medically indicated AND a separate culture procedure has NOT yielded the same organism(s).
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Preliminary culture reports available after 24 hours. Culture reports of no growth will be issued after 72 hours. Completion of culture reports may take 3-4 days after receipt of the specimen when multiple isolates are found.
SPECIAL INSTRUCTIONS: The specific anatomic site of the specimen MUST be specified on the order or the requisition.
CONTAINER TYPE: Sealed sterile container
COLLECTION: Aseptically prepare the culture site. Remove the tip or device without contact with adjacent skin. Contamination with normal flora from skin or other body surfaces MUST be avoided since colonizing bacteria not involved in the infectious process may be introduced onto the sample.
SPECIMEN REQUIREMENTS:

Catheter tip

REJECTION CRITERIA: Inappropriate specimen container. Urinary catheter tips (i.e. Foley catheters) are unacceptable specimens for culture.
HANDLING INSTRUCTIONS: Specimen MUST be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: No organisms isolated
LIMITATIONS OF TEST: Specimens MUST be transported to the laboratory IMMEDIATELY to eliminate desiccation of the specimen.
METHODOLOGY: Semi-quantitative culture via Maki method (roll plate technique).
ADDITIONAL INFORMATION: The presence of 15 or more colonies indicates that the catheter is the possible etiologic source of bacteremia and, perhaps, septic thrombophlebitis. Therefore, the presence of fewer than 15 colonies will be reported as a description of the isolate(s) only. Complete identification and susceptibility testing will not be performed. Identification and susceptibility testing, if appropriate, will be performed when 15 or more colonies are present. Susceptibilities are not routinely performed for coagulase-negative staphylococci, alpha-Streptococcus species, and Corynebacterium species unless isolated from a blood culture obtained during the same day. Gram stains are NOT performed.
LAST UPDATED:

5-19-2014

TEST SYNONYM(S):IUD Culture; I.V. Catheter Culture; Routine Culture, Intravenous Devices; Swan-Ganz Tip Culture

Cerebrospinal Fluid VDRL

CERNER / EPIC MNEMONIC: C/VDRL
POE DESCRIPTION: CSF VDRL
CPT CODE:

86592-90

TURNAROUND TIME:

2-4 days

CONTAINER TYPE: CSF collection tubes
SPECIMEN REQUIREMENTS: Cerebrospinal fluid, 1.0 mL
REJECTION CRITERIA: Inappropriate specimen container, insufficient specimen volume, bloody specimen, heat treated specimen.
MINIMUM VOLUME: 0.3 mL
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE:

See Specialty Labs - Search Test Code 2366C

LIMITATIONS OF TEST:

Laboratory is required to report to Public Health Department.

METHODOLOGY: VDRL (contains cardiolipin-cholesterol-lecithin)
ADDITIONAL INFORMATION: When syphilis is latent, CSF is sometimes reactive when serum is not. After treatment, a constantly falling titer (although not always observed) is regarded as representative of effective treatment, although it may take many years for the test to become nonreactive. Patients with reactive CSF VDRL results are reported to the City of Chicago Board of Health. This is mandated by law.
TEST SYNONYM(S):CSF, VDRL; Spinal Fluid VDRL; VDRL, CSF

Culture for Chlamydia

CERNER / EPIC MNEMONIC: C CHLAM
POE DESCRIPTION: CU CHLAMYDIA; C CHLAM
CPT CODE:

87110

TEST INFORMATION: Use to establish the diagnosis of Chlamydia trachomatis infection in suspected cases of conjunctivitis, pneumonitis, urethritis, proctitis and cervicitis. Test includes tissue culture technique for the isolation of Chlamydia trachomatis. Identification of inclusions with monoclonal antibody.
DAYS PERFORMED:

Monday-Friday

TURNAROUND TIME:

3-4 days

CONTAINER TYPE: Viral transport medium (available from Clinical Microbiology Laboratory)
COLLECTION:

Obtain the viral transport medium from the Clinical Microbiology laboratory. Wipe the epithelial cell surface to remove any excess mucus. Discard the swab. Using a second swab, vigorously swab the site to be cultured and place the swab directly into the viral transport medium. Place tissue and/or aspirate specimens directly into the viral transport medium. Specimens should be collected early in the acute phase of the infection first 3-5 days after onset.

SPECIMEN REQUIREMENTS:

Conjunctival swab, posterior nasopharyngeal aspirate, cervical swab, urethral swab, tissue, lymph node aspirate, rectal swab.

REJECTION CRITERIA: Specimen not transported in viral transport medium, improper swab used in obtaining specimen, specimen heavily contaminated with bacteria, inappropriate specimen source, specimen collected with a WOODEN swab.
MINIMUM VOLUME: 1 mL or swab submitted in viral transport medium.
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE: No Chlamydia isolated
LIMITATIONS OF TEST: The use of viral transport medium is essential to successful culture.
METHODOLOGY: Tissue culture and direct fluorescent antibody (DFA).
REFERRAL LABORATORY:

Commercial

ADDITIONAL INFORMATION: Chlamydia infects the columnar epithelical cells and will not be recovered from squamous epithelial cells or inflammatory cells. In obtaining the specimen, clean the area of inflammatory cells and then attempt to scrape epithelial cells for culturing. Patients in whom Chlamydia trachomatis is isolated are reported to the City of Chicago Board of Health. This is mandated by law.
LAST UPDATED:

5-22-2014

TEST SYNONYM(S):Lymphogranuloma Venereum Culture

Chlamydia Group Antibody Screen and Differentiation Panel

CERNER / EPIC MNEMONIC:

MICRO REF

POE DESCRIPTION:

CHLAMYDIA IGG AB, CHLAMYDIA IGM AB, CHLAMYDIA IGA AB, MICROBIOLOGY REFERRAL

CPT CODE:

86631 x2; 86632; 86631 per species; 86632 per isotype

TEST INFORMATION:

Test includes initial screen to detect IgG, IgM and IgA antibody. When screen positive, a differentiation panel will be performed to determine specific titers and species.

DAYS PERFORMED: Monday-Friday, 0700-1400
TURNAROUND TIME:

1-4 days

CONTAINER TYPE: Red top Vacutainer® tube or SST TM tube
SPECIMEN REQUIREMENTS: Blood (serum)
REJECTION CRITERIA: Excessive hemolysis, gross contamination of the specimen, chylous serum, improper specimen storage, inappropriate specimen container, insufficient specimen volume.
MINIMUM VOLUME:

7 mL blood (1 mL serum)

HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: The screen detects antibody produced against all chlamydial species. The determination of species or type specific antibodies to C. psittaci, C. trachomatis, and the C. pneumoniae is complicated by cross reactive antibody or non-specific stimulation of antichlamydial antibodies. Thus, a panel of Chlamydia must be tested to determine specific titers and establish the strongest reactions.IgM titers of >1:20 are indicative of recent infection with that specific chlamydial agent; however, antichlamydial IgM antibody is very cross reactive and will often demonstrate titers to multiple chlamydial species.

Any IgG titer may indicate past exposure to that particular species. Cross reactive antibody or the presence of nonspecifically stimulated antichlamydial IgG antibody when seen is typically > 1:128. Infection with a particular chlamydial species typically yields antibody titers which are higher than antibody titers to this noninfecting species. IgG titers in recently infected individuals are typically >1:512.

IgA titers may help to identify the infecting Chlamydia species when cross reactive IgG is present. IgA is typically present at low titers during primary Chlamydia infection, but may be elevated in recurrent exposures or in chronic infection.

METHODOLOGY:

Micro-IF

ADDITIONAL INFORMATION:

If attempting to diagnose lymphogranuloma venereum (LGV) infection, request antibodies to chlamydia trachomatis serovars L1, L2 and L3.

LAST UPDATED:

5-20-2014

TEST SYNONYM(S):Chlamydia pneumoniae; Chlamydia psittaci; Chlamydia trachomatis; LGV; Lymphogranuloma Venereum; Psittacosis

Clostridium difficile toxin by PCR

CERNER / EPIC MNEMONIC:

TOXIN CDIF

POE DESCRIPTION:

TOXIN CDIF

CPT CODE:

87493

CDM NUMBER:

3481117

TEST INFORMATION:

Test replaces Clostridium difficile Toxin EIA

DAYS PERFORMED:

Daily

TURNAROUND TIME:

Less than 10 hours

SPECIAL INSTRUCTIONS:

Test not performed on formed stools.  Test not performed on patients less than 2 years of age.  Only one specimen will be tested within a seven day period.

CONTAINER TYPE:

Screw top clean container or white screw top vial included in stool ParaPak collection kit.

COLLECTION:

The specimen should be collected directly into the clean container (no preservative) or into a bedpan, avoiding contamination with urine or water.  Transfer the feces from the bedpan into a clean screw top container.

SPECIMEN REQUIREMENTS:

Fresh unformed stool

REJECTION CRITERIA:

Inappropriate specimen container, insufficient specimen volume, specimen contaminated with urine and/or water, rectal swab, preserved specimen, specimen submitted within the past week, formed stool specimen, child less than two years old, unlabeled or inappropriatedly labeled specimen.

MINIMUM VOLUME:

5 ml or 1 gram

HANDLING INSTRUCTIONS:

Send to the laboratory as soon as possible.  Keep at room temperature.

REFERENCE RANGE:

No Clostridium difficile toxin detected.

LIMITATIONS OF TEST:

Inhibition of the Assay has been observed in the presence of zinc oxide paste and Vagisil cream.

METHODOLOGY:

Real Time PCR

ADDITIONAL INFORMATION:

Contact precautions is required for all patients with diarrhea due to Clostridium difficile for the duration of their illness.

LAST UPDATED:

02-21-12

TEST SYNONYM(S):Clostridium difficile Assay; Clostridium difficile Toxin Test

C1q Complement Component

CERNER / EPIC MNEMONIC: C1Q
POE DESCRIPTION:

C1Q

CPT CODE: 86160-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Red top tube - 4 ml
SPECIMEN REQUIREMENTS:

2.0  mL blood (1.0 mL serum)

REJECTION CRITERIA:

Grossly hemolyzed, grossly lipemic.

MINIMUM VOLUME:

0.5 mL blood (0.1 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 981

LAST UPDATED:

9-8-2014

TEST SYNONYM(S):C1q Complement Protein; Complement C1q

Complement, Total Hemolytic

CERNER / EPIC MNEMONIC: CH50
POE DESCRIPTION: COMPLEMENT TOTAL HEMOLYTIC; CH50
CPT CODE: 86162-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

SSTTM tube

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1 mL blood (0.2 mL serum)

REFERENCE RANGE:

See Specialty Labs  - Search Test Code 1600

LAST UPDATED:

1-24-2012

TEST SYNONYM(S):CH50; Total Hemolytic Complement

Cryoglobulin Detection and Quantitation

CERNER / EPIC MNEMONIC: CRYOGLOB
POE DESCRIPTION: CRYOGLOBULIN
CPT CODE:

82595-90

TEST INFORMATION:

Use this test to determine the presence and quantity of cold insoluble immune complexes in patients with systemic immune complex diseases; determine the presence and quantity of monoclonal cryoglobulins in patients with plasma cell dyscrasias.  If cryoglobulin is present, cryoprecipitate is tested.  Please submit correct volume of blood.

TURNAROUND TIME:

10 working days

SPECIAL INSTRUCTIONS:

Overnight fasting is required. The specimen MUST be kept at body temperature (37°C, 98.6°F) from the time the blood is drawn until delivery to the Core Laboratory. Draw blood into prewarmed tubes, and place tubes in a container of 37°C to 40°C water. Transport to the Core Laboratory, 470 Jelke SC, IMMEDIATELY. Specimen should clot at 37°C.

CONTAINER TYPE:

Three FULL red top Vacutainer (6.0 mL)

COLLECTION:

Specimens accepted Monday through Thursday Only.

SPECIMEN REQUIREMENTS:

18 mL blood (9.0 mL serum).  KEEP BLOOD WARM.

REJECTION CRITERIA:

Specimen not transported on warm water, patient not fasting, specimen hemolyzed, insufficient quantity of specimen, inappropriate specimen container.  Specimen sent Friday through Sunday.

MINIMUM VOLUME:

18 mL blood (9 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 1155

LIMITATIONS OF TEST: Small amounts of fibrin may precipitate at both 4 and 37°C and thus may mask trace amounts of cryoglobulin. False-negative or false low cryoglobulin values occur if blood is allowed to clot below body temperature or if the blood is refrigerated prior to processing.
ADDITIONAL INFORMATION: Cryoglobulins are immunoglobulins which precipitate on cooling and redissolve on warming. If cryoglobulin is present, Cryoprecipitate is tested for IgG, IgM, IgA, RF and IFE. Add 2 to 4 days to turnaround time.
LAST UPDATED:

2-10-2014

TEST SYNONYM(S):Cold Precipitins; Cryoglobulins with Reflex to Cryoprecipitate Immunoglobulins

Cryptococcal Antigen

CERNER / EPIC MNEMONIC:

CRYPTO AG (for CSF), BL CRYPTO (BLOOD)

POE DESCRIPTION: CRYPTOCOCCAL ANTIGEN; CRYPTO AG
CPT CODE:

87327

TEST INFORMATION:

The test is a Lateral Flow Assay which is an immunochromatographic test system  for the detection of Cryptococcal antigen.  This test replaces India Ink preparation for cerebrospinal fluid specimens.

DAYS PERFORMED:

CSF: daily, 24 hours, performed STAT; blood: Daily, 0800-1430

TURNAROUND TIME:

STAT, 2 hours after receipt of the specimen in the laboratory; routine, same day if received by 1330.

CONTAINER TYPE:

Sealed sterile container for CSF, red top Vacutainer® tube for blood

SPECIMEN REQUIREMENTS: Cerebrospinal fluid, blood (serum)
REJECTION CRITERIA: Insufficient quantity of specimen, inappropriate specimen container, hemolyzed blood specimen, bloody cerebrospinal fluid specimen.
MINIMUM VOLUME:

1 mL CSF, 2 mL blood (1 mL serum)

HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE: No cryptococcal antigen detected
LIMITATIONS OF TEST: False negative results may occur due to a low concentration of the polysaccharide antigen or due to a prozone effect at high antigen concentrations. False positive results may occur due to invasive infections with the yeast Trichosporon beigelii,  Capnocytophaga species, or Rothia (Stomatococcus) mucilaginosus.
METHODOLOGY:

Lateral Flow Assay

ADDITIONAL INFORMATION:

A titer will be reported for all positive results. A higher titer usually corresponds with worse disease. Pretreatment of blood specimens with pronase reduces false-positives and increases the sensitivity of the method. A fungal culture should also be performed for patients who are suspected of having cryptococcosis. Antigen detection may precede the detection of viable organisms in cerebrospinal fluid Gram stains and fungal culture. The India Ink preparation has been replaced by the cryptococcal antigen procedure due to the increased sensitivity. A cryptococcal antigen will routinely be performed on all cerebrospinal fluid specimens submitted for a fungal culture providing an adequate volume of specimen is submitted.

LAST UPDATED:

5-20-2014

Cryptosporidium Diagnostic Procedure, Stool

CERNER / EPIC MNEMONIC: SM OOCYST
POE DESCRIPTION: SM CRYPTOSPORIDIUM
CPT CODE: 87207; 87015
TEST INFORMATION: Test includes examination of the stool for the presence of Cryptosporidium, Isospora, and Cyclospora by a modified acid-fast stain.
DAYS PERFORMED:

Daily

TURNAROUND TIME: 1-2 days
CONTAINER TYPE:

Plastic feces specimen container, no preservative; sealed sterile or nonsterile clean container, ECOFIX PARAPAK

COLLECTION: The specimen should be collected directly into the plastic feces specimen container (no preservative) or into a bedpan, avoiding contamination with urine or water. Transfer the feces from the bedpan into the plastic feces container or a sealed container.
SPECIMEN REQUIREMENTS: Fresh stool
REJECTION CRITERIA: Specimen on outside of container, insufficient quantity of specimen, rectal swab, inappropriate specimen, specimen submitted in a preservative, specimen contaminated with water and/or urine.
MINIMUM VOLUME: 1 mL or 1 gram
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate
REFERENCE RANGE: No Cryptosporidium detected; No Isospora detected; No Cyclospora detected
LIMITATIONS OF TEST: Organisms are most readily demonstrated in diarrheal stools.
METHODOLOGY: Modified acid-fast stain of a concentrated specimen on air-dried methanol fixed smears (decolorization with 1% sulfuric acid).
ADDITIONAL INFORMATION: If this test procedure is requested on a specimen other than stool, a consultation with the Director or a Supervisor is recommended. Click here for more information about Cryptosporidiosis, Isosporiasis, and Cyclosporiasis
LAST UPDATED:

5-20-2014

Culture for Corynebacterium diphtheriae

CERNER / EPIC MNEMONIC: C DIPHTH
POE DESCRIPTION: CU C DIPHTHERIAE; C DIPHTH
CPT CODE: 87081
TEST INFORMATION: Test includes isolation and identification of Corynebacterium diphtheriae ONLY. Susceptibility testing will NOT be performed.
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Preliminary culture reports are available after 48 hours. Cultures with no growth of C. diphtheriae will be issued after 72 hours. Completion of culture reports from specimens in which C. diphtheriae has been isolated may take at least 4 days after receipt of the specimen.
CONTAINER TYPE: Copan Swab® II, sterile container, Calgiswab®
COLLECTION: Swab throat lesions, the tonsillar crypts, and the nasopharynx. Separate swabs for throat and nasopharynx specimens are desirable. A flexible calcium alginate swab, Calgiswab®, is recommended for obtaining the nasopharyngeal specimen.
SPECIMEN REQUIREMENTS: Throat, nasopharyngeal
REJECTION CRITERIA: Inappropriate specimen container, inappropriate specimen source
MINIMUM VOLUME: One swab
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: No C. diphtheriae isolated
LIMITATIONS OF TEST: Cultures should be obtained from the nasopharynx, as well as, the throat, since 20% of positive cultures can be missed when only one site is cultured.
METHODOLOGY: Inoculation of conventional and selective culture media.
REFERRAL LABORATORY:

Commercial

ADDITIONAL INFORMATION: Culture will be examined for C. diphtheriae ONLY. Isolates of C. diphtheriae are NOT tested for toxin production.
LAST UPDATED:

5-20-2014

TEST SYNONYM(S):Corynebacterium diphtheriae Culture; Diphtheria Culture

Culture for Group A Streptococcus

CERNER / EPIC MNEMONIC:

C STREPA, STREPACUL (Culture for Grp A only)

POE DESCRIPTION: THROAT CULT/FOR BETA STREP; C STREPA
CPT CODE: 86588
TEST INFORMATION: The test includes a direct antigen screen for Group A Streptococcus. A culture for Group A Streptococcus will be performed for direct antigen screen negative specimens ONLY. Susceptibility testing will NOT be performed.
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Antigen screen: 2 hours after receipt of the specimen in the laboratory. Because the sensitivity of the antigen screen test is only 60-70%, a culture is set up for all antigen-negative specimens. Preliminary culture reports are available after 24 hours. Complete culture reports are issued 24-72 hours.
SPECIAL INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
CONTAINER TYPE: Copan Swab® II
COLLECTION: The tongue should be depressed while both the tonsillar pillars and the oropharynx are swabbed. Exudates should be swabbed and the tongue and uvula avoided.
SPECIMEN REQUIREMENTS: Throat
REJECTION CRITERIA: Inappropriate specimen container, insufficient specimen volume, inappropriate specimen source
MINIMUM VOLUME: One swab
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE: Negative for Group A Streptococcus by direct antigen screening. No Group A Streptococcus isolated.
LIMITATIONS OF TEST: A positive antigen screen result can be relied upon as a rational basis to begin therapy. Therefore, a culture is NOT performed. A negative antigen screen result is only presumptive and due to the low sensitivity of the antigen screening technique, a culture will be performed to reasonably exclude the diagnosis of Group A streptococcal infection. Culture will be screened for Group A Streptococcus ONLY. All Group A streptococci are serologically confirmed.
METHODOLOGY: Direct antigen screen: immunochromatographic assay; Culture: isolation on a medium selective for Group A Streptococcus
ADDITIONAL INFORMATION: Group A Streptococcus, Streptococcus pyogenes, is universally susceptible to penicillin and its derivatives; therefore, susceptibility testing is not performed. The sequelae of poststreptococcal glomerulonephritis and rheumatic fever are diminished by early therapy; therefore, timely diagnosis and early institution of appropriate therapy remains important. Timely therapy may reduce the acute symptoms and overall duration of streptococcal pharyngitis.
LAST UPDATED:

6-2-2014

TEST SYNONYM(S):Beta-Hemolytic Strep Culture, Throat; Group A Beta Streptococcus Culture, Throat; Rapid Strep Screen; RoutineThroat Culture; Screening Culture for Group A Beta Streptococcus; Strep Throat Screen

Culture for Group B Streptococcus

CERNER / EPIC MNEMONIC:

C STREP B

POE DESCRIPTION:

CU GROUP B STREPTOCOCCUS; RECTAL CULTURE FOR BETA STREP; VAGINAL CULTURE FOR BETA STREP

CPT CODE: 87081
TEST INFORMATION: Test includes culture in liquid enrichment broth followed by subculture to solid media. Isolation and identification of Group B Streptococcus ONLY.
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME:

1-3 days

SPECIAL INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
CONTAINER TYPE: Copan Swab® II
COLLECTION:

Do not use lubricant on speculum. Cervical mucus should be removed before collecting endocervical specimens. Move the swab from side to side at the site allowing several seconds for absorption of organisms by the swab. Return the swab to the transport tube. A single swab may be used to collect and submit genital/rectal specimens. The genital specimen should be obtained first.

Preferred specimen genital/rectal on pregnant females.

SPECIMEN REQUIREMENTS:

Vaginal, cervical, rectal, or other gynecological specimen.  Vaginal/rectal swab is the optimal specimen for screening pregnant women at 35 - 37 weeks of gestation, results may be compromised if only a vaginal swab is submitted.

REJECTION CRITERIA: Inappropriate specimen container, inappropriate specimen source
MINIMUM VOLUME: One swab
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE: No Group B Streptococcus isolated
LIMITATIONS OF TEST: Specimen will be screened for Group B Streptococcus ONLY. Because Group Streptococcus is uniformly susceptible to penicillin, susceptibility testing will NOT be performed routinely.
METHODOLOGY: Culture in a broth medium selective for Group B Streptococcus followed by subculture to conventional culture media.
LAST UPDATED:

5-19-2014

TEST SYNONYM(S):Group B Beta-Hemolytic Streptococcus Culture; Beta-Hemolytic Group B Streptococcus Culture

Culture for Leptospira

CERNER / EPIC MNEMONIC: MICRO REF
POE DESCRIPTION: MICROBIOLOGY REFERRAL
CPT CODE: 87081
TEST INFORMATION: Test includes culture for Leptospira ONLY.
DAYS PERFORMED: Monday-Friday, 0800-1400
TURNAROUND TIME:

28-32 days

SPECIAL INSTRUCTIONS: The Clinical Microbiology Laboratory MUST be contacted prior to submission of the specimen. The order or requisition MUST state specimen for Leptospira culture. If urine is submitted, the pH MUST be alkaline or neutral, since Leptospira do NOT survive in an acid pH. Repeat cultures may be necessary.
CONTAINER TYPE: Sterile urine container - do NOT use boric acid transport tube; [heparin Vacutainer® tube for blood (plasma), sealed sterile container for CSF

SPECIMEN REQUIREMENTS:

10 mL urine, 5 mL blood (plasma), 1 mL cerebrospinal fluid

REJECTION CRITERIA: Urine specimen submitted in a boric acid transport tube, urine specimen older than 1 hour, acidic urine, blood specimen collected in an inappropriate tube, insufficient specimen volume.
MINIMUM VOLUME:

10 mL urine, 5 mL blood (1 mL plasma), 1 mL CSF

HANDLING INSTRUCTIONS: Specimen must be transported directly to the Clinical Microbiology Laboratory, 1133 Jelke SC, within 1 hour of collection.
REFERENCE RANGE: No Leptospira isolated
LIMITATIONS OF TEST: Specimen will be cultured for Leptospira ONLY; no other organisms will be isolated or identified. Susceptibility testing will NOT be performed.
METHODOLOGY: Conventional culture in specialized medium
REFERRAL LABORATORY: Commercial Laboratory
ADDITIONAL INFORMATION: Leptospirosis in humans is usually associated with occupational exposure. Veterinarians, dairy workers, swineherders, abattoir workers, miners, fish, and poultry processors, and those who work in a rat-infected environment are at increased risk. Leptospiremia occurs during the septicemic acute phase of infection. This phase lasts 4-7 days after which organisms are not recoverable from blood. Culture of blood or cerebrospinal fluid should NOT be ordered after the first week of illness. During the first week of disease, the most reliable means of detecting spirochetes is by direct culturing of cerebrospinal fluid or blood. Urine does not become positive for Leptospira until the second week of disease and then can remain positive for several months. Concentrations of Leptospira in human urine is low and shedding may be intermittent. Therefore, repeated isolation attempts should be made. Serology (acute and convalescent) is recommended.
LAST UPDATED:

5-20-2014

Culture for Neisseria gonorrhoeae Only

CERNER / EPIC MNEMONIC: C GC; C GCGS
POE DESCRIPTION: CU NEISSERIA GONORRHOEAE; CU GC; C GC

CU N GONORRHOEAE & STAIN; CU GC AND STAIN; C GCGS

CPT CODE: 87081 (culture); 87205 (Gram stain)
TEST INFORMATION: Test includes culture for Neisseria gonorrhoeae ONLY. Susceptibility testing is NOT routinely performed.
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Gram stain: 2 hours after receipt of the specimen in the laboratory. Preliminary culture reports are available after 24 hours. Complete culture reports will be issued after 48-72 hours.
SPECIAL INSTRUCTIONS: Order or requisition must state culture for Neisseria gonorrhoeae.
CONTAINER TYPE:

Sealed sterile containerCopanSwabFemaleCopanSwabMale

The swabs may be ordered through SPD #2105023 (female) and #2105024 (male)

SPECIMEN REQUIREMENTS: Body fluid, discharge, pus, swab of genital lesions, urethral discharge, rectal swab, throat swab, vaginal culture, cervical specimen, eye. A less suitable alternative for inpatient specimens ONLY is inoculated modified Thayer-Martin and chocolate agar media (available from the Clinical Microbiology Laboratory).
REJECTION CRITERIA: Inappropriate specimen container, refrigerated specimen, inappropriate specimen source.
MINIMUM VOLUME: 0.5 mL fluid or one swab
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature. NEVER refrigerate.
REFERENCE RANGE: No Neisseria gonorrhoeae isolated
LIMITATIONS OF TEST: Screening for Neisseria gonorrhoeae ONLY; no other organsisms will be identified. Overgrowth by other microorganisms may make it impossible to rule out the presence of Neisseria gonorrhoeae.
METHODOLOGY: Conventional culture utilizing media specifically formulated for isolation of N. gonorrhoeae.
ADDITIONAL INFORMATION: A Gram stain smear has a high sensitivity and specificity in a symptomatic male with urethral discharge (95-99%). Endocervical Gram stain is of little value as the sensitivity is lower (50%) and endemic normal flora have a similar morphologic appearance causing potential false positives. Cervical and/or anal and throat cultures are recommended for women. Cervical cultures have a sensitivity of 80-90%. Although demonstration of gram-negative diplococci in white blood cells in a urethral smear from a symptomatic male is presumptive evidence of gonorrhea and is sufficiently diagnostic to initiate therapy, cultural confirmation should be considered if available. The Gram stain will detect 75% of gonococcal conjunctivitis and 10-20% of gonococcal skin lesions. It is of no value in pharyngitis. Patients from whom N. gonorrhoeae is isolated are reported to the City of Chicago Board of Health. This is mandated by law. A Neisseria gonorrhoeae DNA probe assay is available for rapid detection of this pathogen. Refer to Neisseria gonorrhoeae DNA probe assay for additional information.
TEST SYNONYM(S):Culture for N. gonorrhoeae Only; Culture for GC Only; Gonorrhea Culture; Neisseria gonorrhoeae Culture

Cystic Fibrosis Culture, Sputum

CERNER / EPIC MNEMONIC: C CF PROT
CPT CODE: 87205, 87071
TEST INFORMATION:

Test includes a direct Gram stain, inoculation of routine conventional and selective media, isolation and identification of microorganisms, and susceptibility testing, if appropriate.  Throat specimens do not get GS.

DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME:

Preliminary culture reports are available after 24 hours. Cultures with no growth or normal flora only will be finalized after 5 days. Complete reports of cultures from which pathogens are isolated may take 7-10 days after receipt of the culture depending upon the nature of the microorganisms detected.

SPECIAL INSTRUCTIONS: Order or requisition must state CF patient.
CONTAINER TYPE: Sputum or Leuken`s container
SPECIMEN REQUIREMENTS: Sputum, Leuken`s, tracheal aspirate
REJECTION CRITERIA: Inappropriate specimen container, insufficient volume, inappropriate specimen source. Only one specimen will be accepted per day.
MINIMUM VOLUME: 1 mL
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: Normal upper respiratory flora only
METHODOLOGY:

Inoculation of routine and selective media for Haemophilus species, Staphylococcus aureus, Pseudomonas species and Burkholderia species.

ADDITIONAL INFORMATION: Burkholderia cepacia is identified in the Clinical Microbiology Laboratory. The isolate will be forwarded to the CF Foundation reference laboratory for confirmation and genotyping. The culture report will not be finalized until the reference laboratory confirmation is complete.
LAST UPDATED:

5-20-2014

Cystoscopy, Culture, Routine

CERNER / EPIC MNEMONIC: C SURINE
POE DESCRIPTION: CU CYSTOSCOPIC C&S CU URINE (INVASIVE); CU URINE C&S (INVASIVE)
CPT CODE: 87086
TEST INFORMATION: Test includes isolation and identification of microorganisms; quantitation of microorganisms; susceptibility testing, when appropriate.
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Preliminary culture reports are available after 24-48 hours. Cultures with no growth will be finalized after 48 hours. Complete reports of cultures from which pathogens are isolated may take 2-3 days after receipt of the culture depending upon the nature of the microorganisms detected.
CONTAINER TYPE:

Sealed, sterile urine container or boric acid transport tube

SPECIMEN REQUIREMENTS: Surgically obtained urine from the bladder, left kidney, right kidney; suprapubic aspirate
REJECTION CRITERIA: Inappropriate specimen container, insufficient specimen volume.
MINIMUM VOLUME: 1 mL
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: No growth
METHODOLOGY: Conventional culture
ADDITIONAL INFORMATION: Two dilutions of the specimen are cultured so as to detect a quantity of microorganisms as low as 100 CFU/mL.
LAST UPDATED:

5-20-2014

TEST SYNONYM(S):Suprapubic Urine Culture

Cytomegalovirus (CMV) DNA Quantitation

CERNER / EPIC MNEMONIC: CMVDNAQT
POE DESCRIPTION: CMV DNA QUANTITATION; CYTOMEGALOVIRUS DNA QUANT
CPT CODE: 87497
TEST INFORMATION: This test is used to detect the presence of CMV DNA in peripheral white cells in patients infected with Cytomegalovirus (CMV). Test replaces CMV antigen.
DAYS PERFORMED: Monday, Wednesday and Friday
TURNAROUND TIME: 1-4 days
SPECIAL INSTRUCTIONS: Specimen received no later than 0700 on the day the test is performed. This test cannot be added onto an existing sample.
CONTAINER TYPE: Lavender top Vacutainer® (EDTA) tube
SPECIMEN REQUIREMENTS: Blood (plasma)
REJECTION CRITERIA: Inappropriate specimen container, clotted specimen, refrigerated specimen, insufficient specimen volume, gross contamination of specimen, improper storage.
MINIMUM VOLUME: 2 mL
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE:

<300 copies/mL

LIMITATIONS OF TEST: Studies have shown that the CMV DNA quantitative assay correlates well with CMV antigenemia in immunocompromised patients such as those with HIV infection or those who have received a solid organ or bone marrow transplant. However, the ratio of CMV DNA predictive of CMV disease (versus infection) in each of these patient populations has not been determined with certainty. Furthermore, a negative result does not exclude the possibility of CMV infection since very low levels of infection or sampling error may cause a false negative result or the disease may be restricted to a specific body organ.
METHODOLOGY:

Real-Time PCR

LAST UPDATED:

5-19-2014

TEST SYNONYM(S):CMV DNA Viral Load; CMV Quantitative

Cytomegalovirus (CMV) IgG Antibody

CERNER / EPIC MNEMONIC: CMV IGG
POE DESCRIPTION: CMV IGG ANTIBODY
CPT CODE: 86644
DAYS PERFORMED:

Monday and Friday

TURNAROUND TIME: 1-4 days
CONTAINER TYPE:

Red top Vacutainer® tube or SST TM tube

SPECIMEN REQUIREMENTS:

4 mL blood (2.0 mL serum)

REJECTION CRITERIA: Hemolysis, gross contamination, icteric, lipemic
MINIMUM VOLUME: 2 mL blood (1 mL serum)
REFERENCE RANGE: <0.90 Index Value
METHODOLOGY: Enzyme immunoassay (EIA)
LAST UPDATED:

4-10-2013

TEST SYNONYM(S):CMV IgG

Cytomegalovirus (CMV) IgM Antibody

CERNER / EPIC MNEMONIC: CMV IGM
POE DESCRIPTION: CMV IGM ANTIBODY
CPT CODE: 86645
DAYS PERFORMED:

Monday and Friday

TURNAROUND TIME: 1-4 days
CONTAINER TYPE:

Red top Vacutainer® tube or SST TM tube

SPECIMEN REQUIREMENTS:

4 mL blood (2 mL serum)

REJECTION CRITERIA: Hemolysis, gross contamination, icteric, lipemic
MINIMUM VOLUME: 2 mL blood (1 mL serum)
REFERENCE RANGE: <0.90 Index Value
LAST UPDATED:

4-10-2013

TEST SYNONYM(S):CMV IgM

Culture for Legionella pneumophila

POE DESCRIPTION:

C LEGIONSM

CPT CODE:

87081, 87015

TEST INFORMATION:

The test includes culture for Legionella.

DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME:

Preliminary cultures reports are available after 48 hours. Culture reports of no growth will be issued after 5 days. Completion of culture reports may take 6-7 days after receipt of the specimen, depending upon the nature of the microorganisms isolated.

CONTAINER TYPE: Sealed sterile container; Leuken`s tube
COLLECTION: Specimens are to be collected from a site prepared utilizing aseptic technique. Non-bacteriostatic sterile saline should be used when obtaining washings and/or lavage specimens. Material obtained by needle aspiration (transbronchial lung biopsy) is injected into a sealed sterile container.
SPECIMEN REQUIREMENTS: Lung tissue, other body tissue, pleural fluid, other body fluid, transtracheal aspiration, bronchoalveolar lavage, BAL, and bronchial brushing.
REJECTION CRITERIA: Inappropriate specimen container, insufficient specimen volume.
MINIMUM VOLUME: 2 mL
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE:

No Legionella species isolated

LIMITATIONS OF TEST:

The sensitivity of the culture is 50-80%; however, the specificity is 100%.

METHODOLOGY:

Culture: conventional culture using routine media and media selective for Legionella isolation.

ADDITIONAL INFORMATION: If clinical suspicion of Legionella is high, several specimens may need to be submitted since small numbers of organisms may be present. Legionella species are widespread in the environment and are associated almost exclusively with surface and potable waters or moist environments. Click here for more information about Legionnaire''s disease.
LAST UPDATED:

5-20-2014

Culture for Nocardia

CERNER / EPIC MNEMONIC: C FUNGUSSM
POE DESCRIPTION: CU FUNGUS W SMEAR (NON-SKIN); C FUNGUSSM (NON-SKIN)
CPT CODE: 87102; 87206
TEST INFORMATION: Test includes a culture for fungi and performance of a direct fungal smear. All fungal isolates will be identified. Other isolated organisms (i.e. aerobes, mycobacteria, etc.) may be referred for identification and/or susceptibility testing if medically indicated AND a separate culture procedure has NOT yielded the same organism(s).
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: Smear results: same day if the specimen is received in the laboratory no later than 1400. Preliminary culture reports are available after 1 week or when a fungal isolate is detected. Cultures will be finalized after 4 weeks.
SPECIAL INSTRUCTIONS: The specific anatomic site of the specimen MUST be specified on the order or the requisition. The order or the requisition MUST be labeled to rule out the presence of Nocardia spp.
CONTAINER TYPE: Copan Swab® II, sterile sputum container, sterile Leuken`s tube, sterile container, no preservative
COLLECTION: The specimen of choice is an aspirate or tissue, NOT a swab. Specimens are to be collected from a site prepared utilizing aseptic technique. Overlying and adjacent areas must be carefully prepared to eliminate surface (normal flora) anaerobes. Ideally, material is obtained by needle aspiration through an intact surface, which has been cleaned with antiseptic, then placed directly into a sealed sterile container. Sampling of open lesions is enhanced by deep aspiration using a sterile plastic catheter. Curetting of the base of an open lesion is optimal. If irrigation is necessary, nonbacteriostatic sterile saline may be used. When a syringe is used to obtain the specimen, ALL air should be expelled after which the specimen should be injected into a sealed, sterile container. Swabs should be used as a last resort due to the small volume of specimen obtainable by this method. If a swab must be used, sample the advancing margin of the lesion and abscess walls firmly. Do NOT sample pus or exudate ONLY. Contamination with normal flora from skin or other body sources MUST be avoided since colonizing bacteria and/or saprophytic fungi not involved in the infectious process may be introduced into the sample. The sputum and Leuken`s specimens should be first morning specimens. Nonbacteriostatic saline should be used when irrigation is necessary
SPECIMEN REQUIREMENTS: Purulent fluid material appropriately obtained from a wound, sputum, bronchial, sterile body fluids
REJECTION CRITERIA: Inappropriate specimen container, insufficient specimen volume.
MINIMUM VOLUME: 0.5 mL
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE:

No fungus isolated/observed

LIMITATIONS OF TEST: A single negative culture does NOT rule out the presence of nocardial infection. Swabs should be submitted ONLY when aspirated purulent fluid, exudate, or biopsy material cannot be obtained.
METHODOLOGY: Smear: modified acid-fast stain. Culture: Conventional culture utilizing media specifically formulated for fungal isolation.
ADDITIONAL INFORMATION: Specimens from lesions suspected of containing Nocardia species should also be examined for Actinomyces species. A separate specimen should be submitted for Actinomycosis Special Anaerobe Culture. The portion of the surgical specimen submitted to the Clinical Microbiology Laboratory should be aseptically separated from the portion submitted to the Pathology Department.
LAST UPDATED:

5-19-2014

Complement Profile

CERNER / EPIC MNEMONIC: COMP PROF
POE DESCRIPTION: COMPLEMENT PROFILE; COMP PROF
CPT CODE:

 

TEST INFORMATION: Profile includes C3, C4, CH50, Clq.  Tests available individually.
DAYS PERFORMED:

C3, C4 - Daily, 24 hours

CH50, Clq - Core Lab Referral Tests

TURNAROUND TIME:

1-3 days

CONTAINER TYPE:

Red top tube - 10 mL or SST Tube

SPECIMEN REQUIREMENTS:

10 mL blood (5.0 mL serum)

REJECTION CRITERIA: Hemolysis
MINIMUM VOLUME: 5 mL blood (2.5 mL serum)
REFERENCE RANGE: Normal Ranges for Common Laboratory Tests  
METHODOLOGY:

Turbidometric

CD34 Progenitor Cell Quantitation

CERNER / EPIC MNEMONIC: CD34 COUNT
CPT CODE: 88180 (x2)
TEST INFORMATION: METHOD - Immunophenotyping
DAYS PERFORMED: Mon-Fri, 0800-1600 (no holidays)
TURNAROUND TIME: 24 hours
SPECIAL INSTRUCTIONS: Test requires viable cells; specimen must be collected fresh and delivered to the laboratory within 24 hours of draw time.
CONTAINER TYPE: Yellow top (ACD) tube, lavender top (EDTA) tube, or green top (sodium heparin) tube
SPECIMEN REQUIREMENTS: Blood, Leukapheresis product, bone marrow, or cord blood
MINIMUM VOLUME: 0.5 mL peripheral blood, apheresis, cord blood, or bone marrow
HANDLING INSTRUCTIONS: Transport specimen immediately to the laboratory at room temperature, within 24 hours of collection.
TEST SYNONYM(S):Precursor Cells; Stem Cell Enumeration

CD4/CD8

CERNER / EPIC MNEMONIC: CD4/CD8
POE DESCRIPTION: CD4/CD8
CPT CODE: 86360
TEST INFORMATION: METHOD - Immunophenotyping
DAYS PERFORMED: Mon-Thur, 0800-1600; Fri, 0800-1400; days preceding holidays, 0800-1400 (no holidays)
TURNAROUND TIME: 2 days
CONTAINER TYPE: Lavender top (EDTA) tubes
SPECIMEN REQUIREMENTS: Blood
MINIMUM VOLUME: Two tubes (2.5 mL) whole blood
HANDLING INSTRUCTIONS: Do not refrigerate. Deliver to the laboratory within 24 hours.
REFERENCE RANGE: Normal ranges are included with the report.
CRITICAL VALUES:

test

TEST SYNONYM(S):T-Lymphocytes; T-Cell Subsets

Chorionic Villi Chromosome Studies

CERNER / EPIC MNEMONIC: CHROM-CVS
POE DESCRIPTION: CHORIONIC VILLI CHROM STUDIES; CHROM-CVS
CPT CODE: 88235, 88267, 88291, 88261
DAYS PERFORMED: Mon-Fri, 0800-1500; must arrange with laboratory in advance
TURNAROUND TIME: 10-12 days
SPECIAL INSTRUCTIONS: Laboratory technician must be present to evaluate sample on location; must have completed history and consent forms.
CONTAINER TYPE: Contact Genetics Laboratory, 942-6298
SPECIMEN REQUIREMENTS: Chorionic villi from 8-10 weeks gestation
MINIMUM VOLUME: 10 mg
REFERENCE RANGE: Written interpretation by Unit Director of Genetics Laboratory
TEST SYNONYM(S):Chorionic Villi Sampling (CVS)

Chromosome, Blood

CERNER / EPIC MNEMONIC: CHROM-BLD
POE DESCRIPTION: CHROMOSOME BLOOD; CHROM-BL
CPT CODE: 82262, 88230, 88291
DAYS PERFORMED: Mon-Fri, 0800-1530
TURNAROUND TIME: 5-10 days
SPECIAL INSTRUCTIONS: Completed patient history form MUST be submitted with specimen. Contact the Genetics Laboratory (312-942-6298) for required form and additional information.
CONTAINER TYPE: Sterile green top (heparin) tube
SPECIMEN REQUIREMENTS: Sterile blood
MINIMUM VOLUME: 2 mL
HANDLING INSTRUCTIONS: If not sent to Genetics Laboratory immediately, refrigerate specimen (4°C) and deliver to the laboratory as soon as possible.
TEST SYNONYM(S):Chromosome, Lymphocytes

Chromosome, Fibroblasts

CERNER / EPIC MNEMONIC: CHROM-FIB
POE DESCRIPTION: CHROMOSOME FIBROBLASTS; CHROM-FIB
CPT CODE: 88262, 88233, 88291
DAYS PERFORMED: Weekdays, 0800-1530
TURNAROUND TIME: 3-4 weeks
SPECIAL INSTRUCTIONS: Completed patient history form MUST be submitted with specimen. Contact the Genetics Laboratory (312-942-6298) for required form and additional information.
CONTAINER TYPE: Any sterile, chemically clean, securely capped container of appropriate size containing sterile 0.9% saline
SPECIMEN REQUIREMENTS: Potentially viable tissue which must be obtained by aseptic technique; in the case of skin, full thickness biopsy 5 mm²
MINIMUM VOLUME: 3 mm²
HANDLING INSTRUCTIONS: Do not freeze. Place in sterile saline and refrigerate (4°C).
TEST SYNONYM(S):Chromosome, Skin (or Various Other Tissues)

Cystathionine Synthase

CERNER / EPIC MNEMONIC: CYST SYNTH
POE DESCRIPTION: CYSTATHIONINE SYNTHASE; CYST SYNTH
CPT CODE: 82658
TEST INFORMATION: See OMIM information
DAYS PERFORMED: Mon-Fri, 0800-2400
TURNAROUND TIME: 4-6 weeks
CONTAINER TYPE: Sterile container with sterile saline or media
SPECIMEN REQUIREMENTS: Skin biopsy
MINIMUM VOLUME: 3 mm³
HANDLING INSTRUCTIONS: Transport to the laboratory immediately.
REFERENCE RANGE: 3.7-55.3 µM cystathionine produced/135 minutes/mg protein

Carnitine

CERNER / EPIC MNEMONIC: CARNITINE
POE DESCRIPTION: CARNITINE
CPT CODE: 82379-90
TURNAROUND TIME: 5-7 working days
SPECIAL INSTRUCTIONS:

This test cannot be added onto an existing sample.

CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS: 4.0 mL blood (2.0 mL serum)
MINIMUM VOLUME: 2.0 mL blood (1.0 mL serum)
REFERENCE RANGE: See Specialty Labs - Search Test Code 4163

CKMB

CERNER / EPIC MNEMONIC: CKMB
POE DESCRIPTION: CKMB (INCLUDES CK)
CPT CODE: 82550, 82553
CDM NUMBER: 3061059, 3061207
TEST INFORMATION: Test includes CK, CKMB, CKMB INDEX
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: 1 hour
CONTAINER TYPE:

Red top tube - 4 mL or SST tube

SPECIMEN REQUIREMENTS:

4.0 mL blood (2.0 mL serum)

MINIMUM VOLUME: 1 mL blood (0.5 mL serum)
METHODOLOGY: Chemiluminescent Microparticle Immunoassay (CMIA)

Cardiolipin IgA

CERNER / EPIC MNEMONIC: CARLIP IGA
POE DESCRIPTION: CARDIOLIPIN AB IGA
CPT CODE: 86147-90
TEST INFORMATION:

Included as part of the Antiphospholipid Profile.

TURNAROUND TIME:

5-7 working days

 

CONTAINER TYPE:

SSTTM tube or red top tube

SPECIMEN REQUIREMENTS:

2 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1 mL blood (0.6 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 3374

TEST SYNONYM(S):Anti-Cardiolipin IgA antibody

C-Peptide

CERNER / EPIC MNEMONIC: C-PEPTIDE
POE DESCRIPTION: C-PEPTIDE
CPT CODE: 84861-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS: 6.0 mL blood (3.0 mL serum)
MINIMUM VOLUME: 2.0 mL blood (0.8 mL serum)
REFERENCE RANGE: See Specialty Labs - Search Test Code 3140
TEST SYNONYM(S):Connecting Peptide; C-Peptide Reactivity; Endogenous Insulin; Insulin C-Peptide; Proinsulin C-Peptide; CPR

C1 Esterase Inhibitor Activity

CERNER / EPIC MNEMONIC: C1EST ACT
POE DESCRIPTION: C1 ESTERASE INHIB ACTIVITY; C1EST ACT
CPT CODE: 86161-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Red top tube only
SPECIMEN REQUIREMENTS: 4.0 mL blood (2.0 mL serum)
MINIMUM VOLUME: 1.0 mL blood (0.4 mL serum)
REFERENCE RANGE: See Specialty Labs - Search Test Code 1531

C1 Esterase Inhibitor, Protein Quantitation

CERNER / EPIC MNEMONIC: C1EST QT
POE DESCRIPTION: C1EST QT
CPT CODE: 86160-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Red top tube
SPECIMEN REQUIREMENTS: 2.0 mL blood (1.0 mL serum)
MINIMUM VOLUME: 1.0 mL blood (0.5 mL serum)
REFERENCE RANGE: See Specialty Labs - Search Test Code 1530
TEST SYNONYM(S):C1 Inhibitor; Hereditary Angioedema Test

C2 Complement

CERNER / EPIC MNEMONIC: C2
POE DESCRIPTION: C2 COMPLEMENT
CPT CODE: 86160-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS: 2.0 mL blood (1.0 mL serum)
MINIMUM VOLUME: 0.5 mL blood (0.1 mL serum)
REFERENCE RANGE:

See Specialty Labs - Search Test Code S51758

C5 Complement

CERNER / EPIC MNEMONIC: C5
POE DESCRIPTION: C5 COMPLEMENT
CPT CODE: 86160-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS: 2 mL blood (1.0 mL serum)
MINIMUM VOLUME: 0.5 mL blood (0.1 mL serum)
REFERENCE RANGE:

See Specialty Labs - Search Test Code S51759

CA 19-9

CERNER / EPIC MNEMONIC: CA 19-9
POE DESCRIPTION: CA 19-9
CPT CODE: 86301-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

SSTTM tube or red top tube

SPECIMEN REQUIREMENTS: 2 mL blood (1.0 mL serum)
MINIMUM VOLUME: 1mL blood (0.5 mL serum)
REFERENCE RANGE:

See Quest Diagnostics - Search Test Code 4698

TEST SYNONYM(S):Carbohydrate antigen 19-9

CA27.29

CERNER / EPIC MNEMONIC: CA27.29
POE DESCRIPTION: CA27.29
CPT CODE:

86300

TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

SSTTM tube or red top tube

SPECIMEN REQUIREMENTS: 2 mL blood (1.0 mL serum)
REJECTION CRITERIA:

Gross hemolysis

MINIMUM VOLUME: 1 mL blood (0.5 mL serum)
REFERENCE RANGE:

See Quest Diagnostics - Search Test Code 29493

CRP, High Sensitivity

CERNER / EPIC MNEMONIC: HSCRP
POE DESCRIPTION: HIGH SENSITIVITY CRP
CPT CODE: 86141-90
TEST INFORMATION: Used as a cardiac risk factor
TURNAROUND TIME:

Routine:  8 hours

STAT:     1 hour

CONTAINER TYPE:

SSTTM tube or red top tube

SPECIMEN REQUIREMENTS: 2.0 mL blood (1.0 mL serum)
MINIMUM VOLUME: 1.0 mL blood (0.5 mL serum)
REFERENCE RANGE:

Low Risk:    0.10 - 0.99 mg/L

Mod Risk:    1.0 - 3.0 mg/L

High Risk:    >3.0 mg/L

LAST UPDATED:

6-6-2013

TEST SYNONYM(S):High sensitivity CRP; Cardio CRP

Calcitonin

CERNER / EPIC MNEMONIC: CALCITONIN
POE DESCRIPTION: CALCITONIN
CPT CODE: 82308-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE: See Specialty Labs  - Search Test Code 3126

LAST UPDATED:

1-24-2012

TEST SYNONYM(S):Thyrocalcitonin

Calculi Analysis (Renal)

CERNER / EPIC MNEMONIC: CALCULI
POE DESCRIPTION: RENAL CALCULI ANALYSIS; CALCULI
CPT CODE: 82365-90
TURNAROUND TIME: 5-7 working days 
SPECIAL INSTRUCTIONS: Specify source of stone on requisition.
CONTAINER TYPE: Plastic urine container
SPECIMEN REQUIREMENTS: Kidney stones
MINIMUM VOLUME: Entire specimen
REFERENCE RANGE: See Specialty Labs  - Search Test Code 4155
TEST SYNONYM(S):Kidney Stone Analysis; Renal Calculi; Stone Analysis; Calculus Analysis

Carbamazepine, Total and Epoxide

CERNER / EPIC MNEMONIC: CARB/EPOX
POE DESCRIPTION: CARBAMAZEPINE AND EPOXIDE
CPT CODE: 80156, 80157-90
TEST INFORMATION: includes total and epoxide
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Red top tube - 10 mL or Red top tube - 4 mL
SPECIMEN REQUIREMENTS: 4.0 mL blood (2.0 mL serum)
MINIMUM VOLUME:

1.5 mL blood (0.7 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code S40960

METHODOLOGY:

HPLC

TEST SYNONYM(S):Carbamazepine Metabolite; Carbamazepine-10, 11-Epoxide, Serum

Carbohydrate Deficient Transferrin - Congenital Disorder

CERNER / EPIC MNEMONIC:

CDT CONG

POE DESCRIPTION:

CDT Congenital Disorder

CPT CODE:

82373-90

TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

SSTTM tube or red top tube

SPECIMEN REQUIREMENTS: 2 mL blood (1.0 mL serum)
MINIMUM VOLUME: 1 mL blood (0.5 mL serum)
REFERENCE RANGE:

See Specialty Labs - Search Test Code - S51679

LAST UPDATED:

6-6-2013

TEST SYNONYM(S):CDT Congenital Disorder; Carbohydrate Deficient Transferrin - Congenital Disorder of Glycosylation (CDG)

Carotene

CERNER / EPIC MNEMONIC: CAROTENE
POE DESCRIPTION: CAROTENE, CAROT
CPT CODE: 82380-90
TURNAROUND TIME: 5-7 working days
SPECIAL INSTRUCTIONS:

This test cannot be added onto an existing sample.  Patients should fast for 12 hours, and cannot consume alcohol for 1 day.

CONTAINER TYPE:

Red top tube only or SSTTM tube

SPECIMEN REQUIREMENTS: 4.0 mL blood (2.0 mL serum)
MINIMUM VOLUME: 2.0 mL blood (1.0 mL serum)
HANDLING INSTRUCTIONS: Must be protected from light after serum is separated.
REFERENCE RANGE: See Specialty Labs - Search Test Code 3998

TEST SYNONYM(S):Beta Carotene

Catecholamines, Fractionation, Urine

CERNER / EPIC MNEMONIC: U/CATECH
POE DESCRIPTION: U/CATECH
CPT CODE:

82384-90

TEST INFORMATION:

Test includes urine total catecholamines, epinephrine, norepinephrine and dopamine.

TURNAROUND TIME: 5-7 working days
SPECIAL INSTRUCTIONS:

If possible, patient should discontinue all drugs at least one week prior to collection.  Medications known to interfere with this assay include:  Alpha-methyldopa (Aldomet), Isoproterenol, Labetalol, Mandelamine, Metaclopramide, Acetaminophen (high concentrations only), Cimetidine, and Catecholamine-containing drugs, MAO inhibitors, diuretics, vasodilators.  Other interfering substances include smoking and drinking tea and coffee within four hours of collecting specimen.

CONTAINER TYPE:

24-hour urine bottle Chemistry bottle #1

SPECIMEN REQUIREMENTS: 24-hour urine
MINIMUM VOLUME: Submit entire urine collection to the laboratory.
HANDLING INSTRUCTIONS: Keep refrigerated during collection.
REFERENCE RANGE: See Specialty Labs - Search Test Code 3304U

LAST UPDATED:

3-11-2014

TEST SYNONYM(S):Epinephrine, Urine; Fractionation, Urinary Free; Free Cathecholamine Fractionation; Norepinephrine, Urine; Dopamine, Urine; Urine Catecholamines

Catecholamines, Blood

CERNER / EPIC MNEMONIC: CATECH FR
POE DESCRIPTION: CATECHOLAMINES FRACTIONATED; CATECH FR
CPT CODE: 82384-90
TURNAROUND TIME: 5-7 working days
SPECIAL INSTRUCTIONS:

If possible, patient should discontinue all drugs at least one week prior to collection.  Medications known to interfere with this assay include: Alpha-methyldopa (Aldomet), Isoproterenol, Labetalol, Mandelamine, Metaclopramide, Acetaminophen (high concentrations only), Cimetidine, and Catecholamine-containing drugs, MAO inhibitors, diuretics, vasodilators.  Other interferng substances include smoking and drinking tea  and coffee within four hours of collecting specimen.  This test cannot be added onto an existing sample.

CONTAINER TYPE:

Green top (heparin) tube delivered to lab on ice

SPECIMEN REQUIREMENTS: 6 mL whole blood (3.0 mL heparinized plasma)
REJECTION CRITERIA:

Specimen not delivered on ice immediately after collection.

MINIMUM VOLUME: 3.0 mL whole blood (1.5 mL heparinized plasma)
REFERENCE RANGE:

See Specialty Labs - Search Test Code 3304

TEST SYNONYM(S):Adrenalin., Plasma; Dopamine, Plasma; Epinephrine, Plasma; Fractionated Catecholamines Plasma; Noradrenaline, Plasma; Norepinephrine, Plasma

Chloride, Feces: 24, 48 or 72 hrs

CERNER / EPIC MNEMONIC: Q/CL
POE DESCRIPTION: FEC CHLORIDE; FEC CL; Q/CL
CPT CODE:

82438-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

One or more stool collection containers. Containers available from Core Laboratory

SPECIMEN REQUIREMENTS: 24, 48, or 72-hour stool collection. Submit entire collection to the laboratory. Specimen must be liquid.
HANDLING INSTRUCTIONS: Keep refrigerated during collection.
REFERENCE RANGE:

See Quest Diagnostics - Search Test Code 8831

TEST SYNONYM(S):Chloride, Stool; Fecal chloride

Chromogranin A

CERNER / EPIC MNEMONIC: CHROMO-A
POE DESCRIPTION:

CHROMOGRANIN-A

CPT CODE:

86316-90

TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

SSTTM tube or red top tube

SPECIMEN REQUIREMENTS: 2.0 mL blood (1.0 mL serum)
MINIMUM VOLUME: 1.0 mL blood (0.5 mL serum)
REFERENCE RANGE:

See Specialty Labs - Search Test Code S51768

Chronic Granulomatous Disease

CERNER / EPIC MNEMONIC: CGD
POE DESCRIPTION: CHRONIC GRANULOMATOUS DISEASE; NBT; CGD
CPT CODE:

82657-90

TURNAROUND TIME: 7-10 days
SPECIAL INSTRUCTIONS: Must be received in lab by NOON, Monday through Thursday only.
CONTAINER TYPE: Green top (heparin) tube
SPECIMEN REQUIREMENTS: 10 mL (sodium heparin) whole blood
MINIMUM VOLUME: 7 mL (sodium heparin) whole blood - green top microtainer tube
REFERENCE RANGE:

See Focus Diagnostics - Search Test Code 20474

TEST SYNONYM(S):Neutrophil Function, Oxidative Burst; NBT

Citric Acid, Urine

CERNER / EPIC MNEMONIC: U/CIT
POE DESCRIPTION: URT CITRATE; U/CIT
CPT CODE:

82507-90

TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

24-hour urine bottle

, containing 10 grams boric acid (Chemistry bottle #3)

SPECIMEN REQUIREMENTS: 24-hour urine
MINIMUM VOLUME: Entire collection
HANDLING INSTRUCTIONS: Keep refrigerated during collection
REFERENCE RANGE: See Specialty Labs - Search Test Code - 3970U

TEST SYNONYM(S):Urine Citrate

Clomipramine

CERNER / EPIC MNEMONIC: CLOM
POE DESCRIPTION: CLOMIPRAMINE
CPT CODE: 83789-90
TEST INFORMATION: Includes desmethylclomipramine
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Red top tube only
SPECIMEN REQUIREMENTS: 6.0 mL blood (3.0 mL serum)
REJECTION CRITERIA:

SST tubes not acceptable.

MINIMUM VOLUME: 4.0 mL blood (2.0 mL serum)
REFERENCE RANGE: See Specialty Labs  - Search Test Code 4962

TEST SYNONYM(S):Anafranil

Clonazepam

CERNER / EPIC MNEMONIC: CLONAZ
POE DESCRIPTION: CLONAZEPAM; CLONAZ
CPT CODE: 80154-90
TURNAROUND TIME: 5-7 working days
SPECIAL INSTRUCTIONS:

Optimum time to collect sample: immediately before the administration of the next dose.

CONTAINER TYPE: Red top tube only
SPECIMEN REQUIREMENTS: 4.0 mL blood (2.0 mL serum)
REJECTION CRITERIA:

SST tubes not acceptable

MINIMUM VOLUME:

2.0 mL blood (1.0 mL serum)

REFERENCE RANGE: See Specialty Labs - Search Test Code 4918

TEST SYNONYM(S):Klonopin(TM)

Clozapine and Norclozapine

CERNER / EPIC MNEMONIC: CLOZAPINE
POE DESCRIPTION: CLOZAPINE
CPT CODE:

80159-90

TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Green top tube
SPECIMEN REQUIREMENTS: 4.0 mL blood (2.0 mL heparinized plasma)
MINIMUM VOLUME: 2.0 mL blood (1.0 mL heparinized plasma) 
REFERENCE RANGE: See Specialty Labs - Search Test Code 4964

LAST UPDATED:

1-15-2014

TEST SYNONYM(S):Clozaril; Norclozapine

C1Q Binding Assay

CERNER / EPIC MNEMONIC: C1Q BIND
POE DESCRIPTION: CIQ BINDING ASSAY; C1Q BIND
CPT CODE: 86332-90
TURNAROUND TIME: 5-7 working days
SPECIAL INSTRUCTIONS:

This test cannot be added onto an existing sample.

CONTAINER TYPE:

Red top tube or SSTTM tube

SPECIMEN REQUIREMENTS: 2.0 mL blood (1.0 mL serum)
MINIMUM VOLUME: 1.0 ml blood (0.5 ml serum)
REFERENCE RANGE: See Specialty Labs - Search Test Code S51585

TEST SYNONYM(S):Immune Complex Clq Binding Assay

Compound S

CERNER / EPIC MNEMONIC: COMP-S
POE DESCRIPTION: 11-DEOXYCORTISOL SPECIFIC; COMP-S; COMP SP and 11 DEOXYCORTISOL METOPIRONE; COMPS-MET
CPT CODE: 82634-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Red top tube
SPECIMEN REQUIREMENTS: 2.0 mL blood (1.0 mL serum)
MINIMUM VOLUME: 0.5 mL blood (0.3 mL serum)
REFERENCE RANGE: See Specialty Labs - Search Test Code S51410
TEST SYNONYM(S):11-Deoxycorticosterone

Copper, Blood

CERNER / EPIC MNEMONIC: COPPER
POE DESCRIPTION: COPPER BLOOD; COPPER
CPT CODE: 82525-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE: Dark blue top tube Vacutainer® #6526 (no anticoagulant). No other tube.
SPECIMEN REQUIREMENTS: 4.0 mL blood (2.0 mL serum)
MINIMUM VOLUME: 2.0 mL blood (1.0 mL serum)
REFERENCE RANGE: See Specialty Labs - Search Test Code 4870

TEST SYNONYM(S):Cu, Blood

Copper, Urine

CERNER / EPIC MNEMONIC: U/CU
POE DESCRIPTION: URT CU; U/CU
CPT CODE: 82525-90
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

 

24-hour urine bottle - Chemistry bottle #5

SPECIMEN REQUIREMENTS: 24-hour urine
MINIMUM VOLUME: Submit entire urine collection to the laboratory.
HANDLING INSTRUCTIONS: Keep refrigerated during collection.
REFERENCE RANGE: See Quest Diagnostics -Search Test Code 365

TEST SYNONYM(S):Cu, Urine; Urine Copper

Cortisol, Urinary Free

CERNER / EPIC MNEMONIC: U/CORTISOL
POE DESCRIPTION: URT CORTISOL; U/CORTISOL
CPT CODE:

82530-90

TURNAROUND TIME:

5-7 working days

SPECIAL INSTRUCTIONS: Requisition must state date and time collection started and date and time collection finished.
CONTAINER TYPE:

24-hour urine bottle, Chemistry bottle #3 (containing10 gm boric acid)

SPECIMEN REQUIREMENTS: 24-hour urine
MINIMUM VOLUME: Submit entire collection to the laboratory.
HANDLING INSTRUCTIONS: Keep refrigerated during collection.
REFERENCE RANGE:

 

See Specialty Labs- Search Test Code S51655

 

 

TEST SYNONYM(S):Urinary Free Cortisol; Urine Cortisol

Cyclic AMP

CERNER / EPIC MNEMONIC: C-AMP
POE DESCRIPTION: C-AMP
CPT CODE: 82030-90
TURNAROUND TIME: 5-7 working days
SPECIAL INSTRUCTIONS:

This test cannot be added onto an existing sample.

CONTAINER TYPE: Lavender top (EDTA) tube
SPECIMEN REQUIREMENTS: 2.0 mL blood (1.0 EDTA plasma)
MINIMUM VOLUME: 0.5 mL blood (0.1 EDTA plasma)
REFERENCE RANGE: See Specialty Labs - Search Test Code S49068

TEST SYNONYM(S):AMP, Cyclic; C-AMP

Coagulation Profile

CERNER / EPIC MNEMONIC:

Order individually

POE DESCRIPTION: COAGULATION PROFILE
CPT CODE: 85730; 85384; 85610; 85670
TEST INFORMATION:

Test includes APTT, FIBRINOGEN, PT, Thrombin Time.

DAYS PERFORMED: Daily, 24 hours.
TURNAROUND TIME: Routine: 4 hours; stat 1 hour
CONTAINER TYPE: Blue top (sodium citrate) tube
COLLECTION:

See Section - 'Specimen Collection Guidelines' - Coagulation Specimens

SPECIMEN REQUIREMENTS: Blood (plasma)
MINIMUM VOLUME: 1.5 mL plasma
HANDLING INSTRUCTIONS: Transport the specimen to the laboratory as soon as possible. Specimen MUST be received within 4 hours after collection.
TEST SYNONYM(S):Coagulation Panel; Coagulation Screening Panel

Chromosome, Bone Marrow

CERNER / EPIC MNEMONIC: CHROM-SPEC
POE DESCRIPTION: CHROMOSOME BONE MARROW; CHROM-SPEC
CPT CODE: 88262, 88237, 88291
DAYS PERFORMED: Mon-Fri, 0800-1500
TURNAROUND TIME: 3-10 days
SPECIAL INSTRUCTIONS: Completed patient history form MUST be submitted with specimen. Contact the Genetics Laboratory (312-942-6298) for required form and additional information.
CONTAINER TYPE: Sterile green top (heparin) tube
SPECIMEN REQUIREMENTS: Sterile bone marrow
MINIMUM VOLUME: 2.0 mL
HANDLING INSTRUCTIONS: Maintain specimen at room temperature. Deliver immediately to the laboratory.
TEST SYNONYM(S):Bone Marrow Cytogenetics; Bone Marrow Karyotype

Cystine, Urine Quantitative 24 hr

CERNER / EPIC MNEMONIC: U/CYST
POE DESCRIPTION: URT CYST, U/CYST
CPT CODE: 82131-90, 81050, 82570-90 
TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

24 hr urine collection, Chemistry bottle #1 (no preservative)

SPECIMEN REQUIREMENTS:

24 hour urine

MINIMUM VOLUME:

Submit entire collection to the laboratory.

HANDLING INSTRUCTIONS:

Keep refrigerated during collection.

REFERENCE RANGE:

See Specialty Labs - Search Test Code 3962U

REFERENCE CHART: See laboratory report.
METHODOLOGY: Spectrophotometry
LAST UPDATED:

1-19-2012

TEST SYNONYM(S):Urine Cystine

Cystine, 24-Hour Urine

CERNER / EPIC MNEMONIC:

U/CYST

POE DESCRIPTION: URINE CYST TIMED
CPT CODE:

82131-90

CDM NUMBER: 3181062, 3061065
TEST INFORMATION:

Test includes random urine creatinine.

TURNAROUND TIME: 5-7 days
CONTAINER TYPE:

24-hour urine bottle containing (Chemistry Bottle #3) or (Chemistry Bottle #4)

SPECIMEN REQUIREMENTS: 24-hour urine
MINIMUM VOLUME: Entire collection
REFERENCE RANGE:

See Specialty Labs - Search Test Code 3962U

Cyclic Citrullinated Peptide Antibody

CERNER / EPIC MNEMONIC:

CCP AB

POE DESCRIPTION:

Cyclic Citrullinated Peptide Ab

CPT CODE:

86200-90

CDM NUMBER:

3181384

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top tube

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 3133

METHODOLOGY:

Enzyme Immunoassay

TEST SYNONYM(S):CCP Antibodies, Anti-CCP

Cyanide, blood

CERNER / EPIC MNEMONIC:

CYANIDE

POE DESCRIPTION:

Cyanide

CPT CODE:

82600-90

CDM NUMBER:

3181390

TURNAROUND TIME:

4-6 hours

CONTAINER TYPE: Gray top tube
SPECIMEN REQUIREMENTS:

5 mL oxalated whole blood

MINIMUM VOLUME:

3 mL oxalated whole blood

REFERENCE RANGE:

See Quest Diagnostics - Search Test Code 400

CRITICAL VALUES:

Potentially toxic: >0.5 mg/L

Carnitine, urine

CERNER / EPIC MNEMONIC:

MISC CHEM

CPT CODE:

82379-90

CDM NUMBER:

3181385

TEST INFORMATION:

Test includes total carnitine, free carnitine and acyl to free ratio

TURNAROUND TIME:

7-10 days

CONTAINER TYPE:

Random urine cup

SPECIMEN REQUIREMENTS:

3.0 mL random urine

MINIMUM VOLUME:

1.0 mL random urine

REFERENCE RANGE:

See Mayo Clinic - Search Test Code 81123

METHODOLOGY:

Tandem mass spectrometry

TEST SYNONYM(S):Urine carnitine, random

Cashew (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

CASHEW

POE DESCRIPTION:

Cashew Nut Allergen

CPT CODE:

86003-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code F202

Cat epithelium (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

CAT

POE DESCRIPTION:

Cat Epithelium Allergen

CPT CODE:

86003-90

TEST INFORMATION:

Included in the Rast Inhalant Panel.

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs  - Search Test Code E1

TEST SYNONYM(S):Cat dander allergen

Catfish (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

CATFISH

POE DESCRIPTION:

Catfish Allergen

CPT CODE:

86003-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code S51888

Clodasporium herbarum (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

C. HERBARUM

POE DESCRIPTION:

Cladosporium herbarum allergen

CPT CODE:

86003-90

TEST INFORMATION:

Mold allergen, included in the Rast Inhalant Panel.

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code - M2

Clam (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

CLAM

POE DESCRIPTION:

Clam Allergen

CPT CODE:

86003-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code F207

Cockroach (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

ROACH

POE DESCRIPTION:

Cockroach Allergen

CPT CODE:

86003-90

TEST INFORMATION:

Included in the Rast Inhalant Panel.

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code I6

Codfish (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

CODFISH

POE DESCRIPTION:

Codfish allergen

CPT CODE:

86003-90

TEST INFORMATION:

Included in the Rast Food Panel.

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code F3

Corn (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

CORN

POE DESCRIPTION:

Corn Allergen

CPT CODE:

86003-90

TEST INFORMATION:

Included in the Rast Food Panel.

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code F8

Cottonwood tree (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

COTTONWOOD

POE DESCRIPTION:

Cottonwood Allergen

CPT CODE:

86003-90

TEST INFORMATION:

Included in the Rast Inhalant Panel.

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code T14

Crab (IgE) Rast Allergen

CERNER / EPIC MNEMONIC:

CRAB

POE DESCRIPTION:

Crab Allergen

CPT CODE:

86003-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SSTTM tube or red top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.3 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code F23

Calprotectin

CERNER / EPIC MNEMONIC:

Q/CALPROT

CPT CODE:

83993-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

Clean, leak proof plastic container

SPECIMEN REQUIREMENTS:

1 grams of stool

MINIMUM VOLUME:

0.3 grams of stool

REFERENCE RANGE:

See Specialty Labs - Search Test Code S52034

TEST SYNONYM(S):Fecal Calprotectin

Chloride, Fluid

CERNER / EPIC MNEMONIC:

F/CL

POE DESCRIPTION:

FLUID CHLORIDE

CPT CODE:

82438

DAYS PERFORMED:

Specimen accepted daily, 24 hours

TURNAROUND TIME:

1 hour

SPECIAL INSTRUCTIONS:

Must specify fluid type on the requisition.

CONTAINER TYPE:

Red top tube - 10 mLRed top tube - 4 mLSterile 80 mL specimen container

SPECIMEN REQUIREMENTS:

Body fluid

MINIMUM VOLUME:

0.2 mL

REFERENCE RANGE:

None established

TEST SYNONYM(S):Fluid Chloride

Congenital Central Hypoventillation Syndrome (CCHS)

CERNER / EPIC MNEMONIC:

CCHS DNA

POE DESCRIPTION:

CCHS DNA

CPT CODE:

81479

CDM NUMBER:

3301025, 3301023, 3301110, 3301059

DAYS PERFORMED:

Mon-Fri, 0800-1500

TURNAROUND TIME:

2 weeks

SPECIAL INSTRUCTIONS:

Download order form

CONTAINER TYPE:

Lavender top (EDTA) tube

SPECIMEN REQUIREMENTS:

7 mL

REJECTION CRITERIA:

Hemolyzed blood

MINIMUM VOLUME:

3 mL

HANDLING INSTRUCTIONS:

Leave specimen at room temperature and deliver to the laboratory as soon as possible. If sample must be stored overnight, put in refrigerator.  DO NOT FREEZE.

REFERENCE RANGE:

Normal alleles contain 20 repeats although non-disease causing deleted variants with 14 and 15 repeats have been seen in the normal population.  CCHS-associated alleles contain 25-33 repeats.

METHODOLOGY:

PCR analysis of the region in exon 3 of PHOX2b coding for the CCHS-associated polyalanine repeat expansion mutation is conducted using primers flanking this region.  The number of alanine-coding triplet repeats in each PHOX2b allele is quantitated via polyacrylamide gel electrophoresis of the PCR product and compared with known standard alleles.

LAST UPDATED:

2-4-2014

TEST SYNONYM(S):PHOX2b Gene

Complete Blood Count

CERNER / EPIC MNEMONIC:

CBC

POE DESCRIPTION:

COMPLETE BLOOD COUNT

CPT CODE:

85025

TEST INFORMATION:

Test includes: WBC, RBC, HGB, HCT, PLT, & RBC indices

DAYS PERFORMED:

Daily, 24 hours; available stat

TURNAROUND TIME:

8 hours; stat Hematology Panel; 1 hour

CONTAINER TYPE:

Lavender top (K2 EDTA) tube

SPECIMEN REQUIREMENTS:

Blood

REJECTION CRITERIA:

- Clotted or hemolyzed specimen

- CBC, >24 hours old

MINIMUM VOLUME:

1.5 mL venous, 250 µL capillary whole blood

HANDLING INSTRUCTIONS:

Specimen should be sent to the laboratory as soon as possible.

REFERENCE RANGE:

See Table 1

REFERENCE CHART:

Microcytosis evaluation

LAST UPDATED:

11-21-2013

TEST SYNONYM(S):Blood Count

Coccidioides Ab Complement Fixation

CERNER / EPIC MNEMONIC:

COCCIAB CF

CPT CODE:

86635

CDM NUMBER:

3181446

TURNAROUND TIME:

3 - 7 days

CONTAINER TYPE:

red top Vacutainer tube or SST tube

SPECIMEN REQUIREMENTS:

Serum

REJECTION CRITERIA:

Improper storage of specimen, inappropriate specimen container, insufficient specimen volume

MINIMUM VOLUME:

1 mL

HANDLING INSTRUCTIONS:

Specimen should be transported as soon as possible.  When transportation is delayed, refrigerate.

REFERENCE RANGE:

<1:2

METHODOLOGY:

Complement Fixation

REFERRAL LABORATORY:

Commercial Laboratory

ADDITIONAL INFORMATION:

All serum titers >=1:2 must be considered presumptive evidence of coccidioidomycosis, although titers of 1:2 and 1:4 should be confirmed by immunodiffusion testing.  Titers exceeding 1:16 usually reflect disseminated disease.  A negative CF test does not rule out the diagnosis.  Patients with cavitary disease are only 70% positive and with nodular diseases, only 30 % positive.

LAST UPDATED:

2-3-2012

TEST SYNONYM(S):Fungal Antibodies; Serum Fungal Profile

CRE Screen

CERNER / EPIC MNEMONIC:

CRE SCREEN

CPT CODE:

87081

TEST INFORMATION:

This is a screening test for carbapenemase producing gram negative bacilli.

DAYS PERFORMED:

Daily, 24 hours

TURNAROUND TIME:

1 - 2 days

CONTAINER TYPE:

Copan Swab II

SPECIMEN REQUIREMENTS:

Stool, rectal Swab or inguinal area skin swab if a rectal swab cannot be obtained

REJECTION CRITERIA:

Inappropriate specimen container or inappropriate source

MINIMUM VOLUME:

One swab

HANDLING INSTRUCTIONS:

Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.

REFERENCE RANGE:

SCEEEN NEGATIVE for carbapenemase production

METHODOLOGY:

Culture

LAST UPDATED:

12-17-2013

TEST SYNONYM(S):KPC SCREEN

Coccidioides Quantitative Antigen EIA

CERNER / EPIC MNEMONIC:

COCCI  AG

CPT CODE:

87449

CDM NUMBER:

3181503

TEST INFORMATION:

Intended use is as an aid in diagnosis of  coccidioidomycosis or to monitor therapy.

DAYS PERFORMED:

Test performed  Monday - Friday only.

TURNAROUND TIME:

2 - 7 days

CONTAINER TYPE:

Sealed sterile urine container (no preservative); red top Vacutainer tube or SST tube; sealed sterile cerebrospinal fluid collection tube; sealed sterile sputum or Leuken's container.

SPECIMEN REQUIREMENTS:

Urine, serum separated from the clot, plasma separated from the red cell layer, CSF, bronchial, or other sterile body fluid

REJECTION CRITERIA:

Inadequate specimen volume, particulate matter or viscosity that would not allow the specimen to be pipetted.

MINIMUM VOLUME:

2.0 mL

HANDLING INSTRUCTIONS:

Store in refrigerator if not sent the same day as obtained.

REFERENCE RANGE:

Negative = None Detected, Low Positive = 0.1-1.2 ng/ml, Moderate Positive = 1.3-8.2 ng/ml, High Positive = Above the Limit of Quantification

LIMITATIONS OF TEST:

Cross-reactions occur in histoplasmosis and possibly blastomycosis.  Sputolysin and NaOH treatment degrade the analyte detected in the assay.  Negative results do not exclude coccidioidomycosis:  testing both urine and serum offers the highest sensitivity.

METHODOLOGY:

Quantitative sandwich enzyme immunoassay (EIA)

REFERRAL LABORATORY:

Commercial Laboratory

Cystic Fibrosis Screen

CERNER / EPIC MNEMONIC:

Cystic Fib

CPT CODE:

81220-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

Lavender top (EDTA) tube

SPECIMEN REQUIREMENTS:

4.0 mL whole blood

MINIMUM VOLUME:

3.0 mL whole blood

REFERENCE RANGE:

See Specialty Labs - Search Test Code 10458

LAST UPDATED:

4-15-2013

TEST SYNONYM(S):Cystic Fibrosis Mutations

Cortisol, Saliva

CERNER / EPIC MNEMONIC:

SAL/CORTSL

CPT CODE:

82530-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

Salivette tube (obtain from Send Out Lab)

COLLECTION:

PRECAUTIONS:

1. Saliva should be collected at the time(s) prescribed by your
doctor. 2. No food or fluids for 30 minutes prior to collection.
3. Do not use any creams, lotions, or steroid inhalers immediately
prior to collection. 4. Avoid any activity that can cause your gums
to bleed, including brushing and flossing your teeth. Consult with
your doctor if this is a chronic problem. 5. Do not use this kit on
children under 3 years of age or any patient with increased risk of
swallowing or choking.

INSTRUCTIONS FOR COLLECTION:

1. Rinse mouth thoroughly with water and discard. Do not swallow.
2. Hold the Salivette(R) at the rim of the suspended insert and
remove the stopper. 3. Remove the swab. 4. Place the swab under the
tongue until well saturated, approximately 1 minute. 5. Return the
saturated swab to the suspended insert and close the Salivette(R)
firmly with the stopper. 6. Do not remove the tube holding the
insert. The Salivette(R) should be sent to the lab with the swab
inside. 7. Label the Salivette(R) with the patient name, date and
time of collection, and any other identifying information. The
Salivette(R) may be refrigerated if they cannot be sent to the
laboratory within 24 hours of collection.

 

SPECIMEN REQUIREMENTS:

0.5 mL saliva

REJECTION CRITERIA:

Any tube other than SALIVETTE will be rejected.

MINIMUM VOLUME:

0.2 mL saliva

REFERENCE RANGE:

See Specialty Labs - Search Test Code S52400

LAST UPDATED:

4-16-2013

Centromere Autoantibodies

CERNER / EPIC MNEMONIC:

Centromere

CPT CODE:

86038-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SST or Red Top

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 1109

LAST UPDATED:

4-16-2013

TEST SYNONYM(S):ACA; Anti-centromere antibodies

Carbohydrate Deficient Transferrin - Alcohol Use

CERNER / EPIC MNEMONIC:

CDT ETH

CPT CODE:

82373-90, 84466-90

TURNAROUND TIME:

5-7 working days

SPECIAL INSTRUCTIONS:

Deliver to the Core Lab immediately.

CONTAINER TYPE:

SST tube or red top tube

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE:

See Quest Labs - Search Test Code - 16985

LAST UPDATED:

6-6-2013

TEST SYNONYM(S):CDT - alcohol use

CSF West Nile Virus AB IgM

CERNER / EPIC MNEMONIC:

C/WNV IGM

CPT CODE:

86788-90

TURNAROUND TIME:

5-7 working days

SPECIMEN REQUIREMENTS:

1.0 mL CSF

MINIMUM VOLUME:

0.7 mL CSF

REFERENCE RANGE:

See Quest Labs - Search Test Code 16013

LIMITATIONS OF TEST:

Cross reactivity has been observed between alphavirus group and flavivirus group, e.g., yellow fever or yellow fever vaccination

LAST UPDATED:

9-18-2013

TEST SYNONYM(S):West Nile Virus IgM CSF

Culture for Chlamydia

CERNER / EPIC MNEMONIC:

CHLAM CUL

CPT CODE:

87110, 87140

TEST INFORMATION:

Use to establish the diagnosis of Chlamydia trachomatis infection in suspected cases of conjunctivitis,  pneumonitis, urethritis, proctitis and cervicitis.  Test includes tissue culture technique for the isolation of Chlamydia trachomatis. Identification of inclusions with monoclonal antibody.

DAYS PERFORMED:

Monday - Saturday

TURNAROUND TIME:

4 -5 days

CONTAINER TYPE:

Viral transport medium (available from Clinical Microbiology Laboratory)

COLLECTION:

Obtain the viral transport medium from the Clinical Microbiology laboratory. Wipe the epithelial cell surface to remove any excess mucus. Discard the swab. Using a second swab, vigorously swab the site to be cultured and  place the swab directly into the viral transport medium. Place tissue and/or aspirate specimens directly into the viral transport medium.

SPECIMEN REQUIREMENTS:

Conjunctival swab, posterior nasopharyngeal aspirate, throat swab, cervical swab, urethral swab, tissue, sputum, lymph node aspirate and rectal swab without feces.

REJECTION CRITERIA:

Specimen not transported in viral transport medium, specimen heavily contaminated with bacteria, inappropriate specimen source, specimen collected with a wooden shaft or calcium alginate swab, tissues in formalin or other fixatives.

MINIMUM VOLUME:

1mL or swab submitted in viral transport medium.

HANDLING INSTRUCTIONS:

Specimen should be transported as soon as possible. When transportation is delayed refrigerate for 48 hours, or freeze at -70 degrees C.  Ship frozen.

REFERENCE RANGE:

No Chlamydia isolated

LIMITATIONS OF TEST:

The use of viral transport medium is essential to successful culture.

METHODOLOGY:

Tissue culture and direct fluorescent antibody (DFA).

REFERRAL LABORATORY:

Quest Diagnostics

ADDITIONAL INFORMATION:

Chlamydia infects the columnar epithelial cells and will not be recovered from squamous epithelial cells or inflammatory cells. In obtaining the specimen, clean the area of inflammatory cells and then  attempt to scrape epithelial cells for culturing. Patients in whom Chlamydia trachomatis is isolated are reported to the City of Chicago Board of Health. This is mandated by law.

LAST UPDATED:

9-11-2013

TEST SYNONYM(S):Chlamydia trachomatis culture; Lymphogranuloma Venereum Culture

Chromosome Amniotic Inpatient

CERNER / EPIC MNEMONIC:

=CHROMAF

CPT CODE:

88235-90, 88269-90, 88280-90, 88291-90

TEST INFORMATION:

Restricted test for L&D and MBU only

TURNAROUND TIME:

8-10 days

CONTAINER TYPE:

sterile container

SPECIMEN REQUIREMENTS:

20.0 mL clear, amniotic fluid

MINIMUM VOLUME:

5.0 mL clear amniotic fluid

REFERENCE RANGE:

See Quest Labs - Search Test Code 14590

ADDITIONAL INFORMATION:

no stat availability

LAST UPDATED:

10-1-2013

Congenital Adrenal Hyperplasia PEDS

CERNER / EPIC MNEMONIC:

CAH Panel

CPT CODE:

82157-90, 82634-90, 82533-90, 82626-90, 84143-90, 84144-90, 83498-90, 84403-90, 82633-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

Red top only or Red microtainer

SPECIMEN REQUIREMENTS:

1.0 mL blood (0.5 mL serum)

MINIMUM VOLUME:

0.5 mL blood (0.25 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 90398

LAST UPDATED:

1-24-2014

Cotinine

CERNER / EPIC MNEMONIC:

Cotinine

CPT CODE:

83887-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

RED TOP TUBE ONLY

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

REJECTION CRITERIA:

Serum from an SST tube, grossly hemolyzed samples

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 90642

LAST UPDATED:

3-11-2014

TEST SYNONYM(S):Nicotine and Cotinine

Celiac Disease Eval with IgA

CERNER / EPIC MNEMONIC:

CELIAC EVL

CPT CODE:

82784-90, 83516-90 x3, 86255-90 x2

TEST INFORMATION:

Includes IgA results

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

SST or Red top

SPECIMEN REQUIREMENTS:

4.0 mL blood (2.0 mL serum)

MINIMUM VOLUME:

4.0 mL blood (2.0 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 1075

LAST UPDATED:

6-20-2014

Cystatin C

CERNER / EPIC MNEMONIC:

CYSTATIN C

CPT CODE:

82610-90

TURNAROUND TIME:

5-7 working days

CONTAINER TYPE:

Red top only

SPECIMEN REQUIREMENTS:

1.0 mL blood (0.5 mL serum)

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code S51640

LAST UPDATED:

6-20-2014