Parvovirus B19 Antibody

CERNER / EPIC MNEMONIC:

Parvo B19

CPT CODE:

86747X2

TEST INFORMATION:

This test includes testing for IgG and IgM antibodies to Parvovirus B19

DAYS PERFORMED:

Monday - Friday

TURNAROUND TIME:

3 - 7 days

SPECIAL INSTRUCTIONS:

It is the responsibility of the requesting physician to see that both acute and convalescent specimens are obtained. The physician should arrange for the collection of the convalescent serum 14- 28 days after the acute is collected. Paired testing of acute and convalescent phase sera is recommended, if clinically indicated.

CONTAINER TYPE:

Red top Vacutainer tube or SST tube

SPECIMEN REQUIREMENTS:

Blood  (serum)

REJECTION CRITERIA:

Excessive hemolysis, gross contamination of specimen, chylous serum, improper storage of specimen, inappropriate specimen container, insufficient specimen volume.

MINIMUM VOLUME:

5 mL blood (1mL serum)

HANDLING INSTRUCTIONS:

Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.

REFERENCE RANGE:

Parvovirus B19 AB IgG = <0.9,  Parvovirus B19 AB IgM = <0.9  Refer to Quest Test Code 8946.

METHODOLOGY:

Enzyme Immunoassay  (EIA)

REFERRAL LABORATORY:

Quest Diagnostics

ADDITIONAL INFORMATION:

This test determines the presence of Parvovirus B19 infection which can cause Fifth disease in children, aplastic anemia in immunocompromised individuals, aplastic crisis in chronic hemolytic anemia patients, and "Lyme-like" arthritis in the absence of serological evidence of B. burgdorferi infection. Specific IgG antibodies are usually detected in 2-3 weeks after exposure, reach peak concentrations, and then decline, but remain detectable for years. Specific IgM antibodies are detected 1-2 weeks after exposure, reach peak concentrations and then decline to undetectable concentrations within 2-3 months after exposure.

LAST UPDATED:

9-11-2013

TEST SYNONYM(S):Human Parvovirus Antibody; Fifth's Disease; Human Parvovirus B19 IgG