Coccidioides Ab Complement Fixation

CERNER / EPIC MNEMONIC:

COCCIAB CF

CPT CODE:

86635

CDM NUMBER:

3181446

TURNAROUND TIME:

3 - 7 days

CONTAINER TYPE:

red top Vacutainer tube or SST tube

SPECIMEN REQUIREMENTS:

Serum

REJECTION CRITERIA:

Improper storage of specimen, inappropriate specimen container, insufficient specimen volume

MINIMUM VOLUME:

1 mL

HANDLING INSTRUCTIONS:

Specimen should be transported as soon as possible.  When transportation is delayed, refrigerate.

REFERENCE RANGE:

<1:2

METHODOLOGY:

Complement Fixation

REFERRAL LABORATORY:

Commercial Laboratory

ADDITIONAL INFORMATION:

All serum titers >=1:2 must be considered presumptive evidence of coccidioidomycosis, although titers of 1:2 and 1:4 should be confirmed by immunodiffusion testing.  Titers exceeding 1:16 usually reflect disseminated disease.  A negative CF test does not rule out the diagnosis.  Patients with cavitary disease are only 70% positive and with nodular diseases, only 30 % positive.

LAST UPDATED:

2-3-2012

TEST SYNONYM(S):Fungal Antibodies; Serum Fungal Profile