Legionella Urinary Antigen

CERNER / EPIC MNEMONIC:

LEGION AG

POE DESCRIPTION:

LEGION AG

CPT CODE:

87449

TEST INFORMATION:

The Legionella Urinary Antigen  test is an in vitro rapid immunochromatographic assay for the qualitative detection of Legionella pneumophila serogroup 1 antigen

DAYS PERFORMED:

Daily, 24 hours

TURNAROUND TIME:

2 hours

CONTAINER TYPE:

Sterile screw cap  or boric acid tube

COLLECTION:

collect using aseptic technique

SPECIMEN REQUIREMENTS:

 urine,  first void preferred

REJECTION CRITERIA:

specimen received in a preservative other than boric acid, insufficient specimen volume

MINIMUM VOLUME:

2 mL

HANDLING INSTRUCTIONS:

Specimen should be transported as soon as possible.  Specimen may be stored at room temperature for 24 hours. If a longer delay is expected specimen  may be refrigerated for up to 14 days.

REFERENCE RANGE:

Negative

LIMITATIONS OF TEST:

This test will not detect infections caused by other Legionella pneumophila serogroups and by other Legionella species.  A negative antigen result does not exclude infection with Legionella pneumophila serogroup 1.  Culture is recommended for suspected pneumonia to detect causative agents other than Legionella pneumophila serogroup 1 and to recover Legionella pneumophila serogroup 1 when antigen is not detected in urine.

METHODOLOGY:

EIA

ADDITIONAL INFORMATION:

The detection of Legionella pneumophila serogroup 1 antigenuria by EIA is highly sensitive and specific.  Excretion of Legionella antigen in urine may vary depending on the individual patient.  Antigen excretion may begin as early as 3 days after onset of symptons and persist for up to 1 year afterwards.  A positive result can occur due to current or past infection and therefore is not  definitive for infection without other supporting evidence.

TEST SYNONYM(S):Legionnaires Disease