Topiramate

CERNER / EPIC MNEMONIC:

TOPIRAMATE

POE DESCRIPTION:

Topiramate

CPT CODE: 80201-90
CDM NUMBER:

3181322

DAYS PERFORMED:

Monday - Saturday

TURNAROUND TIME: 5-7 working days
CONTAINER TYPE:

 red top tube only

SPECIMEN REQUIREMENTS:

2.0 mL blood (1.0 mL serum)

REJECTION CRITERIA:

Drawn in SST tubes

MINIMUM VOLUME:

1.0 mL blood (0.5 mL serum)

REFERENCE RANGE:

See Specialty Labs - Search Test Code 4925

METHODOLOGY:

Immunoassay

ADDITIONAL INFORMATION: Monitoring plasma Topiramate concentrations is useful for assessing patient compliance, poor seizure control, toxicity, and changes in metabolism or excretion of Topiramate due to the addition of other anticonvulsants to the therapeutic regimen.┐ In clinical trials, Topiramate concentrations have generally ranged from 2-25 mcg/ml.┐ Dose adjustment should be guided by clinical outcome.┐Circulating Topiramate levels have not been correlated to toxicity, adverse effects or clinical efficacy.┐ Results must be interpreted by the clinician with consideration of coadministered drugs and all other confounding factors.
LAST UPDATED:

1-24-2011

TEST SYNONYM(S):Topamax