TORCH Immune Profile

CERNER / EPIC MNEMONIC: TORCH IGG
POE DESCRIPTION: TORCH IGG; TORCH IMMUNE PROFILE; TORCH TITER
CPT CODE: 80090
TEST INFORMATION: The test includes testing for Toxoplasma gondii IgG, Rubella IgG, Cytomegalovirus IgG, Herpes simplex type 1 IgG, and Herpes simplex virus type 2 virus IgG.
DAYS PERFORMED: Tuesday, Friday: Toxoplasma gondii, Herpes simplex Monday-Friday: Rubella
TURNAROUND TIME: 1-4 days
SPECIAL INSTRUCTIONS: Specimen must be received by the laboratory no later than 0800 on the day the test is to be performed.
CONTAINER TYPE: Red top Vacutainer® tube or SSTTM tube
SPECIMEN REQUIREMENTS: Blood (serum)
REJECTION CRITERIA: Excessive hemolysis, gross contamination of specimen, chylous serum, improper storage of specimen, inappropriate specimen container, insufficient specimen volume.
MINIMUM VOLUME: 5 mL blood (1 mL serum)
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: Negative: Rubella, nonimmune; Toxoplasma gondii: not detected; CMV: not detected; Herpes simplex 1: not detected; Herpes simplex 2: not detected
METHODOLOGY: Microparticle enzyme immunoassay (MEIA) and enzyme immunoassay (EIA)
ADDITIONAL INFORMATION: The test is used to screen for IgG antibodies to Toxoplasma gondii, Rubella, Cytomegalovirus, and Herpes simplex viruses. The test is important in newborn infants, and is used to evaluate possible congenital infection. Repeat positive test in 10-14 days and monthly as indicated. If TORCH syndrome is suspected in newborns, individual IgM antibody tests for each of the above antigens should be evaluated and serial specimens tested for changing IgG titers. Toxoplasmosis is reported as IU/mL (International Units); Cytomegalovirus is reported as AU/mL (Antibody Units); Herpes 1 and 2 are reported as REV (Relative EIA values). The cut-off values for positive assays are as follows: Toxoplasma gondii IgG: >6 IU/mL; Cytomegalovirus IgG: >15 AU/mL; Herpes simplex 1: >1 REV; Herpes simplex 2: >1 REV
TEST SYNONYM(S):TORCH Battery; TORCH Screen; TORCH Titer