Rubella Virus IgM Antibody Titer

CERNER / EPIC MNEMONIC: RUB IGM
POE DESCRIPTION: RUBELLA VIRUS IGM AB TITER; RUBELLA IGM; RUB IGM
CPT CODE: 86762
DAYS PERFORMED: Monday-Friday
TURNAROUND TIME: 1-7 days
CONTAINER TYPE: Red top Vacutainer® tube or SSTTM tube
SPECIMEN REQUIREMENTS: Blood (serum)
REJECTION CRITERIA: Excessive hemolysis, gross contamination of specimen, chylous serum, improper storage of specimen, inappropriate specimen container, insufficient specimen volume.
MINIMUM VOLUME: 5 mL blood (1 mL serum)
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: No Rubella IgM antibody detected
METHODOLOGY: Enzyme-linked immunosorbant assay (ELISA)
REFERRAL LABORATORY: Commercial Laboratory
ADDITIONAL INFORMATION: This test is used as an aid in the diagnosis of acute Rubella infection in all patients including neonates. Confirmation of primary Rubella virus infection can be made from a single serum specimen. IgM antibody is present in neonatal serum following congenital infection and increases during the period from birth to 6 months of age. Detection of Rubella specific IgM indicates active infection or recent exposure. Active or recent infection is also demonstrated by a four-fold or greater increase in IgG titer between acute and convalescent sera.