Rapid Helicobacter pylori Urease Test

CERNER / EPIC MNEMONIC: C HPYLORI
POE DESCRIPTION: CU HELICOBACTER PYLORI UREASE
CPT CODE: 87081
TEST INFORMATION: The test detects urease enzyme activity in gastric mucosal biopsy specimens which is usually indicative of the presence of Helicobacter pylori.
DAYS PERFORMED: Daily, 24 hours
TURNAROUND TIME: 2 hours, if test is positive at the time of receipt in the laboratory. Final reports will be issued 24 hours after receipt of the specimen in the laboratory.
CONTAINER TYPE: Selective Rapid Urea medium (available from the Clinical Microbiology Laboratory); sealed sterile container.
SPECIMEN REQUIREMENTS: Gastric mucosal biopsies either inserted in the Selective Rapid Urea medium or transported in sterile saline.
REJECTION CRITERIA:

Inappropriate specimen container, expired Selective Rapid Urea medium, mislabeled/unlabeled specimen.

HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE: No Helicobacter pylori detected
LIMITATIONS OF TEST: An improperly transported specimen may not yield an accurate result. A false positive reaction could result should the medium become contaminated with an alternative urease-producing microorganism. A false negative reaction could result from an insufficient number of microorganisms present in the biopsy material.
METHODOLOGY: Urease reaction in conventional culture medium.
LAST UPDATED:

5-19-2014

TEST SYNONYM(S):CLOtest