Monotest

CERNER / EPIC MNEMONIC: MONOTEST
POE DESCRIPTION: MONO TEST
DAYS PERFORMED:

Routine:  Performed once daily on first and second shifts.

STATS:  Daily - 24 hours

TURNAROUND TIME:

Routine: 1 day

STATS: 1 hour after receipt of the specimen in the laboratory

CONTAINER TYPE:

Red top tube - 4 mL or SST tube

SPECIMEN REQUIREMENTS:

4 mL blood (2 mL serum)

REJECTION CRITERIA: Any hemolysis, chylous serum.
MINIMUM VOLUME: 2 mL blood (1 mL serum)
REFERENCE RANGE: Negative
LIMITATIONS OF TEST: Correlation with clinical findings is imperative since false positive and negative results have been reported. Approximately 10% of the adult population with infectious mononucleosis will not develop heterophile antibodies. Failure to develop heterophile antibodies occurs even more frequently in children. (Refer to Epstein-Barr Viral Capsid Antigen Antibody Titer.) Less than 2% false positives have been reported with Hodgkin`s disease, lymphoma, acute lymphocytic leukemia, infectious hepatitis, pancreatic carcinoma, Cytomegalovirus, Burkitt`s lymphoma, acute lymphocytic leukemia, and rheumatoid arthritis. The simultaneous occurrence of infectious mononucleosis and hepatitis has been reported.
METHODOLOGY:

Rapid latex particle agglutination.

ADDITIONAL INFORMATION: The test detects heterophile antibodies related to infectious mononucleosis.
TEST SYNONYM(S):Heterophile Agglutinins; Monospot