Hepatitis B Virus Core IgM Antibody

CERNER / EPIC MNEMONIC: HBC IGM
POE DESCRIPTION: HEPATITIS B CORE IGM ANTIBODY; HEP B COR IGM AB; HBC IGM
CPT CODE: 86705
TEST INFORMATION: The test includes detection of IgM antibody to Hepatitis B virus core antigen.
DAYS PERFORMED:

Daily, 24 hours

TURNAROUND TIME:

8 hours

CONTAINER TYPE:

Red top Vacutainer® tube or SST TM tube

SPECIMEN REQUIREMENTS: Blood (serum)
REJECTION CRITERIA: Excessive hemolysis, gross contamination of specimen, chylous serum, improper storage of specimen, inappropriate specimen container, insufficient specimen volume.
MINIMUM VOLUME: 5 mL blood (1 mL serum)
HANDLING INSTRUCTIONS: Specimen should be tranported as soon as possible. When transportation is delayed, refrigerate.
REFERENCE RANGE: No Hepatitis B core IgM detected
LIMITATIONS OF TEST: This test should NOT be performed for patients known to have chronic Hepatitis B infection.
METHODOLOGY:

Chemiluminescence

ADDITIONAL INFORMATION: Anti-HBc IgM can be detected in 100% of patients within the first month of illness. The antibody will persist for a variable time period but 96% of patients will become negative by 6 months and 98% negative by 9-12 months. Therefore, this test can only be used for the diagnosis of acute Hepatitis B and NOT to determine the immune status of a patient. Anti-HBc IgM may also be present in acute Hepatitis B in the absence of HBsAg.
LAST UPDATED:

3-28-2013

TEST SYNONYM(S):Anti-HBc IgM; IgM Core Antibody