Cytomegalovirus (CMV) DNA Quantitation

CERNER / EPIC MNEMONIC: CMVDNAQT
POE DESCRIPTION: CMV DNA QUANTITATION; CYTOMEGALOVIRUS DNA QUANT
CPT CODE: 87497
TEST INFORMATION: This test is used to detect the presence of CMV DNA in peripheral white cells in patients infected with Cytomegalovirus (CMV). Test replaces CMV antigen.
DAYS PERFORMED: Monday, Wednesday and Friday
TURNAROUND TIME: 1-4 days
SPECIAL INSTRUCTIONS: Specimen received no later than 0700 on the day the test is performed. This test cannot be added onto an existing sample.
CONTAINER TYPE: Lavender top Vacutainer® (EDTA) tube
SPECIMEN REQUIREMENTS: Blood (plasma)
REJECTION CRITERIA: Inappropriate specimen container, clotted specimen, refrigerated specimen, insufficient specimen volume, gross contamination of specimen, improper storage.
MINIMUM VOLUME: 2 mL
HANDLING INSTRUCTIONS: Specimen should be transported as soon as possible. When transportation is delayed, leave at room temperature.
REFERENCE RANGE:

<300 copies/mL

LIMITATIONS OF TEST: Studies have shown that the CMV DNA quantitative assay correlates well with CMV antigenemia in immunocompromised patients such as those with HIV infection or those who have received a solid organ or bone marrow transplant. However, the ratio of CMV DNA predictive of CMV disease (versus infection) in each of these patient populations has not been determined with certainty. Furthermore, a negative result does not exclude the possibility of CMV infection since very low levels of infection or sampling error may cause a false negative result or the disease may be restricted to a specific body organ.
METHODOLOGY:

Real-Time PCR

LAST UPDATED:

5-19-2014

TEST SYNONYM(S):CMV DNA Viral Load; CMV Quantitative