|CERNER / EPIC MNEMONIC:|
CHLAM IGG; CHLAM IGM; MICRO REF
|POE DESCRIPTION:||CHLAMYDIA IGG AB, CHLAMYDIA IGM AB, MICROBIOLOGY REFERRAL|
|CPT CODE:||86631; 86632; 86631 per species; 86632 per isotype|
|TEST INFORMATION:||Test includes initial screen to detect IgG and IgM antibody. When screen positive, a differentiation panel will be performed to determine specific titers and species.|
|DAYS PERFORMED:||Monday-Friday, 0700-1400|
|TURNAROUND TIME:||1-7 days|
|SPECIAL INSTRUCTIONS:||Acute and convalescent specimens should be submitted with the convalescent specimen submitted 2-3 weeks after the acute. It is the requesting physician`s responsibility to see that both acute and convalescent specimens are obtained.|
|CONTAINER TYPE:||Red top Vacutainer® tube or SST TM tube|
|SPECIMEN REQUIREMENTS:||Blood (serum)|
|MINIMUM VOLUME:||7 mL blood (2 mL serum)|
|HANDLING INSTRUCTIONS:||Specimen should be transported as soon as possible. When transportation is delayed, refrigerate.|
Any IgG titer may indicate past exposure to that particular species. Cross reactive antibody or the presence of nonspecifically stimulated antichlamydial IgG antibody when seen is typically > 1:128. Infection with a particular chlamydial species typically yields antibody titers which are higher than antibody titers to this noninfecting species. IgG titers in recently infected individuals are typically >1:512.
IgA titers may help to identify the infecting Chlamydia species when cross reactive IgG is present. IgA is typically present at low titers during primary Chlamydia infection, but may be elevated in recurrent exposures or in chronic infection.
|METHODOLOGY:||Indirect fluorescent antibody (IFA)|
If attempting to diagnose lymphogranuloma venereum (LGV) infection, request antibodies to chlamydia trachomatis serovars L1, L2 and L3.
|TEST SYNONYM(S):||Chlamydia pneumoniae; Chlamydia psittaci; Chlamydia trachomatis; LGV; Lymphogranuloma Venereum; Psittacosis|