Homocysteine

CERNER / EPIC MNEMONIC: HMCYS
POE DESCRIPTION: HOMOCYSTEINE; PBH; PROTEIN BOUND HOMOCYSTEINE
CPT CODE: 83090
DAYS PERFORMED:

Daily, 24 hours

TURNAROUND TIME:

8 hours

SPECIAL INSTRUCTIONS:

Please deliver immediately to the lab on ice. Homocysteine results may be falsely elevated if whole blood remains at room temperature for more than one hour after collection. If specimens cannot be sent to the lab immediately, they should be placed on ice or immediately centrifuged and plasma aliquoted. This test cannot be added onto an existing sample more than 6 hours old.

CONTAINER TYPE: Lavender topp (K2 EDTA) tube - 3 mL (on ice)
SPECIMEN REQUIREMENTS:

3.0 mL whole blood (1.5 mL EDTA plasma)

REJECTION CRITERIA:

Hemolyzed Sample

MINIMUM VOLUME: 1.0 ml whole blood, 0.3 mL EDTA plasma
HANDLING INSTRUCTIONS:

 

REFERENCE RANGE:

Males: 5.46 - 16.20

Females: 4.44 - 13.56

The total homocystine concentration in plasma or serum of healthy individuals will vary with age, gender, geographical area, and genetic factors.  Values are typically lower for women than for men, however, postmenopausal women may show increased values for total homocystine.  A majority of scientific literature agree upon a range of normal values between 5 and 15 µmol/L (adult male and female).  Values will normally increase with age with accepted expected reference value among elderly (>60 years) from 5 - 20 µmol/L.

METHODOLOGY:

Chemiluminiscent

LAST UPDATED:

3-28-2013