Laboratory is required to report to Public Health Department.
VDRL (contains cardiolipin-cholesterol-lecithin)
When syphilis is latent, CSF is sometimes reactive when serum is not. After treatment, a constantly falling titer (although not always observed) is regarded as representative of effective treatment, although it may take many years for the test to become nonreactive. Patients with reactive CSF VDRL results are reported to the City of Chicago Board of Health. This is mandated by law.