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Rush and Affiliates of Harvard University Receive NIH Grant to Study Alzheimer’s

The National Institutes of Health awarded a new research grant in September to discover, characterize and validate complex molecular networks and candidate genes that influence susceptibility to cognitive decline and Alzheimer’s disease. The grant includes an effort to accelerate the translation of these discoveries into novel treatments.

Philip De Jager, MD, PhD, of Harvard University affiliates Brigham and Women’s Hospital and the Broad Institute, is a principal investigator in the study along with David Bennett, MD, of Rush University Medical Center. The first year of funding is $1.7 million, with an expected total funding of $7.9 million. The Broad Institute and Rush are the lead organizations, collaborating with Brigham and Women’s Hospital and the Pacific Northwest National Laboratories in Richland, Wash.

This award was among several new research grants totaling $45 million that the NIH awarded to advance the National Plan to Address Alzheimer’s Disease, a national effort that aims to find effective interventions for Alzheimer’s by 2025.

“I am gratified that these awards are advancing the research directions that were identified at the NIH-hosted Alzheimer’s Summit of 2012,” said Neil Buckholtz, PhD, director of the Division of Neuroscience at the National Institute on Aging, which leads the NIH Alzheimer’s research program. “The work being done by Drs. DeJager and Bennett and other researchers focused on identifying, characterizing and validating novel therapeutic targets may one day lead to promising targets for interventions for this dread disease.”

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