Rush Medical Center Home Page Information for healthcare Professionals Rush University
FIND A DOCTOR
PATIENT & VISTOR SERVICES
HEALTH INFORMATION
CLINICAL SERVICES
EVENTS & CLASSES
RUSH NEWS ROOM
CLINICAL TRIALS
RESEARCH AT RUSH
NURSING AT RUSH
WORK AT RUSH
GIVING TO RUSH

Bookmark This Page
Health Information In the News: Discover Rush Spring 2013

Treatment for fragile X syndrome, autism

There are plenty of questions and uncertainty when it comes to treatment options for fragile X syndrome and autism. But a recent study provides new possibilities.

Researchers at Rush University Medical Center and the University of California, Davis MIND Institute found that an investigational compound that targets the underlying brain mechanisms in fragile X effectively helps with social avoidance — one of the core deficits in both fragile X and autism spectrum disorders. Fragile X syndrome is the most common known cause of inherited intellectual impairment. It is also the leading known single-gene cause of autism.

The study found that the drug compound STX 209 by Seaside Therapeutics improved symptoms in study participants with fragile X and significant social deficits or autism. Additional studies suggest that

STX 209 may be helpful for autism without fragile X syndrome, as well. This treatment is the first such discovery for fragile X syndrome and, potentially, the first for autism.

"This study will help to signal the beginning of a new era of targeted treatments for genetic disorders that have historically been regarded as beyond the reach of treatment with medications," says Elizabeth Berry-Kravis, MD, PhD, the lead author of the study and a pediatric neurologist at Rush.

Emotional neglect increases risk of stroke

The experiences of your childhood often shape who you are emotionally and mentally. Now research shows that how you were treated as a child can affect your physical health as well.

A study by researchers at the Rush Alzheimer's Disease Center suggests that people who were emotionally neglected as children may have a higher risk of stroke later in adulthood. In the study, participants in the Memory and Aging Project (who did not have dementia and were 55 years of age or older) took a survey measuring physical and emotional abuse before age 18.

Questions focused on whether participants felt loved by their parents or caregivers when they were younger, whether they were made to feel afraid or intimidated, and whether they were punished physically.

The study, published in an online issue of Neurology, found the risk of stroke was nearly three times higher in people who reported a moderately high level of childhood emotional neglect than those who reported a moderately low level.

"The results add to a growing body of evidence suggesting that early-life factors, such as traumatic childhood experiences, influence the development of physical illness and common chronic conditions of old age," says David Bennett, MD, director of the Rush Alzheimer's Disease Center and co-author of the study.

Looking for a Doctor?

Rush University Medical Center in Chicago, is a leader in caring for people of all ages, from newborns through older adults.

Just phone (888) 352-RUSH or (888) 352-7874 for help finding the doctor at Rush who's right for you.

Looking for More Health Information?

Visit Discover Rush's Web Resource page to find articles on health topics and recent health news from Rush University Medical Center in Chicago, Illinois. You will also find many helpful links to other areas of our site.

Looking for Information About Medical Treatment and Services at Rush?

Visit the Clinical Services home page.

Looking for Clinical Trials at Rush?

Visit the Clinical Trials home page.

Promotional Information

Past Issues
Discover Rush Spring 2013
In the News: Discover Rush Spring 2013

   
Find a Doctor | Patient & Visitor Services | Health Information
Clinical Services | Events & Classes | Rush News Room | Clinical Trials
Research At Rush
Disclaimer | Privacy Statement | Site Map

© Rush University Medical Center, Chicago, Illinois