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Clinical Trails at Rush Parkinson Disease Mild Cognitive Impairment Study
Clinical Trial Protocol ID
12060806

Clinical Trial Investigator Name
Jennifer Goldman

Clinical Trial Title

MODERATO – Potential treatment of mild cognitive impairment in patients with Parkinson's disease



Clinical Trial Protocol Description

This is a clinical research study. The purpose of this study is to find out whether the study drug is effective in improving memory function, or cognition, in people with mild cognitive impairment in Parkinson disease (PD-MCI).

Up to 170 subjects will be enrolled in this study across 30 study centers. Approximately six subjects are expected to be enrolled at Rush University Medical Center. Eligible subjects will be randomized (assigned by chance) to receive either an active study drug or placebo (inactive tablet). Subjects will be asked to participate for up to 24 weeks and will include four study visits at the study center.



Clinical Trial Eligibility Criteria

You may be eligible to participate in this study if you:

  • Are 45 through 75 years of age
  • Have a diagnosis of idiopathic Parkinson disease
  • Have mild cognitive impairment but cannot have dementia
  • Are on a stable dopaminergic medication schedule
  • Are able to provide written consent to participate

You will be excluded from this study if you:

  • Have a history of vascular disease (e.g., stroke)
  • Have a history of melanoma (e.g., skin cancer)
  • Have undergone deep brain stimulation (DBS)
  • Have impaired liver function
  • Have pyschosis or are receiving antipsychotic treatment
  • Have taken any investigational products within 60 days prior to the screening/baseline visit

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.





Contact Name Luci Blasucci
Contact Phone (312) 563-2900 ext 4
Contact E-mail clinical_trials@rush.edu
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