Evaluating the safety and effectiveness of an investigational drug compared to placebo when given along with an antidepressant medication in adults with major depressive disorder (MDD).
The purpose of this clinical research study is to see how well an investigational medicine works when taken with an antidepressant, and to see if people experience any side effects while taking this medication. There will be about 1,134 subjects, at about 70 sites globally, participating in this study. We expect to enroll 25 subjects at Rush University Medical Center. Treatment will be assigned randomly. This study consists of 15 office visits.
You may be eligible to participate in this study if you:
- Are having a current depressive episode lasting at least eight weeks
- Are 18-65 years of age
- Are willing to take study medications
You will be excluded from this study if you:
- Have treatment resistant depression
- Have a body mass index (BMI) above 40
- Have substance use/abuse/dependence
- Have a current or past diagnosis of AD/HD
This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.