Autism Spectrum Disorders Treatment Study: This study is looking at the effects of a medication (Namenda) on improving motor planning, memory and speech/language skills in children with autism.

Down Syndrome Symptom Treatment Study: People with Down syndrome can have cognitive problems. Some of these problems include lower-than-average learning, memory and language ability. One of the goals of this study is to find out whether RO5186582 is safe and effective for treating some of these Down syndrome symptoms.

Fragile X Syndrome: Clinical Trial of STX209 for the Treatment of Irritability and Aggression: This is a clinical trial of STX209, which contains only the active form of the two drug forms that are in the drug baclofen which is used to treat irritability and aggression in people with fragile X syndrome (FXS), thus STX209 may be more helpful for people with FXS who have these symptoms.