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Health Information Five Things You Should Know About ... Preventing Cervical Cancer

Silent but deadly. These are words often used to describe cervical cancer — a slow-growing disease that rarely causes symptoms in its early stages. According to the National Cancer Institute, each year more than 11,000 women in the United States are diagnosed with cervical cancer, and for some it will be too late to receive effective treatment.

Cervical cancer is almost always caused by the human papillomavirus (HPV) — the most common sexually transmitted infection. Affecting approximately 20 million Americans, HPV can be detected in 93 percent of all cervical cancers, yet the virus alone is not sufficient to cause cervical cancer. Other contributing factors include oral contraceptive use, poor nutrition, a weakened immune system, pregnancy and smoking.

"Most people never know they have the HPV virus. The vast majority never develop any symptoms, and the body's immune system can usually clear HPV on its own within two years," says Alfred Guirguis, DO, a gynecologic oncologist at Rush University Medical Center. "In some women, however, certain strains of HPV cause changes to the cells in the cervix, which then can become cancerous."

Guirguis offers the following advice for reducing your risk of cervical cancer:

  • Go for routine Pap tests. Pap tests enable doctors to detect abnormalities — changes on the cells on your cervix — and take action before cervical cancer develops. "Women should have a Pap test at least once every three years, beginning about three years after they begin to have sexual intercourse, but no later than age 21. In addition, any bleeding with intercourse should be evaluated by a gynecologist," says Guirguis. According to the American Cancer Society, between 60 and 80 percent of women in the United States with newly diagnosed invasive cervical cancer have not had a Pap test in the past five years. And, even more alarming, many of these women have never had the exam.
  • Follow up on abnormal Pap smears. If an infection is present, your doctor will treat you and repeat the Pap test at a later time. If the examination or Pap test suggests something other than an infection, your doctor will perform other tests to determine the problem. In some cases where women had prior abnormal Pap test results, doctors may also perform an HPV DNA test, which can detect HPV on a woman's cervix.
  • Get vaccinated. Two vaccines, Cervarix and Gardasil, are available to protect girls and women against the types of HPV that cause the most cervical cancers. Your doctor can administer the vaccine in three shots over a six-month period. According to Guirguis, Gardasil is recommended for girls and women between the ages of nine and 26; Cervarix is recommended for girls who are nine years of age, plus women of any age who have not previously been vaccinated and have not previously been diagnosed with cervical cancer. If you aren’t eligible but your daughters are the right ages, consider taking them to be vaccinated.
  • Practice safe sex. Guirguis recommends limiting your number of sexual partners, because studies have shown that women who have many sexual partners increase their risk of developing HPV and their risk of cervical cancer. "And if you are sexually active, use a condom every time you have sex," he says. "Unprotected sex leaves you at risk for contracting sexually transmitted diseases that can increase your risk of getting HPV and greatly increase your chances of developing precancerous changes of the cervix." But while condoms help to lower the risk of developing HPV-related diseases, including cervical cancer, be aware that HPV can infect areas that are not covered by a condom, so condoms may not fully protect against HPV.
  • Quit smoking. Smoking cigarettes doubles your risk of developing cervical cancer, says Guirguis. Studies have shown that tobacco by-products damage the DNA of cervix cells and may contribute to the development of cervical cancer.


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Please note: All physicians featured in Discover Rush Online are on the medical faculty of Rush University Medical Center. Some of the physicians featured are in private practice and, as independent practitioners, are not agents or employees of Rush University Medical Center.

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