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Clinical Services at Rush Center for Neuroendovascular Surgery
Research Studies

Physicians at the Rush Center for Neuroendovascular Surgery are actively involved in research studies to evaluate novel minimally invasive approaches and devices. Patients at the Rush Center for Neuroendovascular Surgery have access to the latest treatments through these research studies. The center's current trials include FRED, SCENT, EPPA, Separator 3D and SWIFT PRIME. For a list of studies throughout Rush, see our clinical trials database.

  • FRED - Flow Re-Direction Endoluminal Device: Pivotal Study of the MicroVention Flow Re-Direction Endolumincal Device Stent System in the Treatment of Intracranial Aneurysms
    The purpose of this study is to evaluate the safety and effectiveness of the MicroVention FRED System when used in the treatment of wide-necked intracranial aneurysms. Subjects with a single target intracranial aneurysm located along the internal carotid artery between the petrous and superior hypophyseal segments are considered for treatment. 
  • The Surpass IntraCranial Aneurysm EmbolizatioN System Pivotal Trial to treat large OR giant wide neck aneurysms (SCENT)
    This study is designed to determine safety and effectiveness of the Surpass Flow Diverter in endovascular treatment of large or giant wide-necked intracranial aneurysms (IA) in the internal carotid artery.
     
  • Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial
    This study aims to determine if hormone replacement therapy given during perimenopause may prevent the progression of saccular cerebral aneurysms. In order to participate you must meet the following inclusion criteria. Generally healthy women, 40-52 years of age. At least one documented saccular intracranial cerebral aneurysm detected via catheter angiography, magnetic resonance angiography or computed tomography angiography. Clinical diagnosis of perimenopause, defined as regular or irregular menses with or without vasomotor symptoms.
     
  • A randomized, concurrent controlled trial to assess the safety and effectiveness of the Separator 3D as a component of the Penumbra System in the revascularization of large vessel occlusion in acute ischemic stroke
    This is a prospective, randomized, concurrent controlled, multi-center study. Patients presenting with symptoms of acute ischemic stroke who have evidence of a large vessel (>3mm in diameter) occlusion in the cerebral circulation will be assigned to either the Penumbra System with the Separator 3D or the Penumbra System without the Separator 3D. Each treated patient will be followed and assessed for 3 months after randomization.
     
  • Solitaire FR With the Intention For Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME)
    The study is a global, multicenter, two┐arm, prospective, randomized, open, blinded endpoint (PROBE) IDE study comparing functional outcomes (defined by mRS) in Acute Ischemic Stroke (AIS) patients with established penumbral mismatch who are treated with either IV t┐PA alone or IV t┐PA in combination with Solitaire FR mechanical thrombectomy intervention.
     

 





Contact Name
Christy Anton
Contact Phone
(312) 942-1489
Contact E-mail
Christy_Anton@rush.edu


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