Rush Medical Center Home Page Information for healthcare Professionals Rush University
FIND A DOCTOR
PATIENT & VISTOR SERVICES
HEALTH INFORMATION
CLINICAL SERVICES
EVENTS & CLASSES
RUSH NEWS ROOM
CLINICAL TRIALS
RESEARCH AT RUSH
NURSING AT RUSH
WORK AT RUSH
GIVING TO RUSH

Bookmark This Page
Clinical Services at Rush Rush Alzheimer's Disease Core Center

Overall Goal

To support the research on etiology, pathogenesis, diagnosis, treatment and prevention of mild cognitive impairment (MCI), Alzheimer's disease (AD) and other common dementias through the activities of six cores. Areas of research include:

  1. Studying the transition from normal aging to MCI and to the earliest stages of dementia, including studies with substantial participation by racial and ethnic minorities;
  2. Studying the neurobiology of normal aging, MCI, AD, and mixed dementias with an emphasis on common coexistng pathologies such as cerebrovascular disease and Lewy bodies;
  3. Linking risk factors for incident MCI and incident AD to post-mortem indices of AD and other common coexisting pathologies;
  4. Incorporating contemporary biochemical and molecular techniques including genomics, epigenomics, proteomics, metabolomics, microarray and next generation sequencing into clinical-pathologic cohort studies of normal aging, MCI, AD and other dementias; and,
  5. Facilitating the overall goals and missions of other federal, state and local agency-supported aging and AD research programs.

Rush ADCC Cores

  1. Administrative Core

    Core Leader:
    David Bennett, MD
    Research Administrator: Annie Barz, MS (Anne_Barz@rush.edu)
    Core Activities: Exercises overall scientific leadership of the Rush ADCC via the executive committee ensuring that each core reaches its scientific goals, and provides leadership for many other national and local aging and AD-related research activities.

  2. Clinical Care Core Leaders: Lisa Barnes, PhD (Lisa_L_Barnes@rush.edu) and Neelum Aggarwal, MD (Neelum_T_Aggarwal@rush.edu)
    Core Activities: Collects the Uniform Data Set (UDS) for the National Alzheimer's Disease Coordinating Center (NACC) and other clinical data compatible with the Religious Orders Study Core, and ante- and post-mortem biospecimens.

  3. Data Management and Statistics Core

    Core Leader:
    Sue Leurgans, PhD (Sue_E_Leurgans@rush.edu)
    Core Activities: Supports data collection by all of the other Cores, manages data in an efficient relational database with appropriate protections of confidentiality, distributes data sets to NACC, and supports the distribution of data and biospecimens to users of Rush ADCC resources. Provides biostatistical expertise and develops novel analytic approaches to the complex longitudinal clinical and neuropathologic datasets created with Center resources.

  4. Neuropathology Core

    Core Leader:
    Julie A. Schneider, MS, MD
    ADC Neuropathology Core Laboratory Manager: Karen Skish, MS (Karen_Skish@rush.edu)
    Core Activities: Employes state-of-the-art procedures to process, store, and distribute ante- and post-mortem biospecimens, obtained from Clinical and Religious Orders Study Core participants, collects the Neuropathology (NP) Data Set for NACC, and other post-mortem data that support a wide range of externally funded studies at Rush and other institutions across the U.S., including studies that incorporate contemporary biochemical and molecular techniques.

  5. Education and Information Transfer Core

    Core Leader:
    Raj C. Shah (Raj_C_Shah@rush.edu)
    Core Activities: Provides multiculturally sensitive educational programs, with an emphasis on racial and ethnic minority communities, in order to build and maintain trusting relationships that support community-based research.

  6. Religious Orders Study Core

    Core Leader:
    David A. Bennett, MD
    Core Activities: Enrolls and follows older Catholic clergy without dementia, including African Americans and Hispanics, all of whom have agreed to annual clinical evaluation and organ donation.




Contact Name
Rush Alzheimer's Disease Center
Contact Phone
312-942-4823
Contact E-mail
Tracy_Faulkner@rush.edu



Location
Armour Academic Center
600 S. Paulina St., Suite 1026
Chicago, IL 60612



Promotional Information

Alzheimer's Disease Center
Neurological Care
Rush Alzheimer's Disease Core Center

   
Find a Doctor | Patient & Visitor Services | Health Information
Clinical Services | Events & Classes | Rush News Room | Clinical Trials
Research At Rush
Disclaimer | Privacy Statement | Site Map

© Rush University Medical Center, Chicago, Illinois