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Clinical Services at Rush Dr. Roy Bakay

Journal Articles

Stover NP, Okun MS, Evatt ML, Raju DV, Bakay RAE, Vitek JL.  Stimulation of the Subthalamic Nucleus in a Patient with Parkinson Disease and Essential Tremor.  Arch Neurol 2005;62: 141-143.

Subramanian T, Deogaonkar M, Brummer M, Bakay RAE, MRI guidance improves accuracy of stereotaxic targeting for cell transplantation and gene therapy in Parkinsonian monkeys. Exp Neurol 2005; 193(1): 172-180.

Tuszynski MH, Thal L, Pay M, Salmon D, Hoi SU, Bakay R, Piyush P, Blesch A, Vahlsing H85L, Ho G, Tong G, Potkin S.G, Fallon, J, Hansen, L, Mufson, EJ, Kordower, JH, Gall C & Conner J.  A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 2005; (doi:10.1038/nm1239) 11:551-555.

Stover SP, Bakay RAE, Subramanian T, Raiser CD, Cornfeldt ML, Scjweikert AW, Allen RC, Watts RL.  Intrastriatal implantation of human retinal pigment epithelial cells attached to microcarriers in advanced Parkinson’s Disease, Arch Neurol 2005; 62:1833-1837.

Bakay RAE, Neural transplantation, J Neurosurg 2005; 103(1): 6-8; discussion 8.

Kutz SC, Bakay RAE.  Deep brain stimulation in patients with non-Parkinson’s movement disorders.  Contemp Neuroscurg 27(3):1-6, 2005.

Vaillancourt DE, Prodoehl J, Sturman MM, Verhagen Metman L, Bakay RAE, Corcos DM. Effects of deep brain stimulation and medication on strength, bradykinesia and electromyographic patterns of the ankle joint in Parkinson’s disease, Mov Disord 2006;21(1):50-58. 

Bakay RAE.  Limits of brain-computer interface.  Neurosurg Focus 2006; 20(5):E6.

Scott T. Grafton, MD, Robert S. Turner, PhD, Michael Desmurget PhD, Bakay RA, MD,       Mahlon Delong, MD, Vitek JL, MD, PhD, Michael Crutcher PhD Normalization of Cortical Activity during Subthalamic Nucleus Stimulation in Parkinson’s Disease, Neurology 2006; 66(8):1192-1199.

Kordower JH, Herzog CD, Bass B, Bakay RAE, Stansell II J, Gasmi M, Bartus RT. Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Ann Neurol 2006;60(6):706-715.

Wang EQ, Verhagen Metman L, Bakay RAE, Arzbaecher J, Bernard B, Corcos DM.  Hemisphere-specific effects of subthalamic nucleus deep brain stimulation on speaking rate and articulatory accuracy of syllable repetitions in Parkinson’s disease. J Med Speech Lang Path 14(4):323-333, 2006.   

Prodoehl J, Corcos DM, Rothwell JC, Verhagen Metman L,, Bakay RAE, Vaillancourt DY.  Effects of STN DBS on memory guided force control in Parkinson’s Disease.  IEEE Transactions on Neural Systems and Rehabilitation Engineering 15(2):155-165, 2007.

Shapiro MB, Vaillancourt DE, Sturman MM, Verhagen Metman L, Bakay RAE, Corcos M.  Effects of STN DBS on rigidity in Parkinson’s Disease.  IEEE Transactions on Neural Systems and Rehabilitation Engineering 15(2):173-181, 2007.

Sani S, Jobe K, Smith A, Kordower JH, Bakay AE. Deep brain stimulation for treatment of obesity in rats.  J Neurosurg 107:809-813, 2007.

Pilitsis JG, Bakay RAE.  Deep brain stimulation for the treatment of Parkinson’s Disease.  Contemp Neurosurg 29(19):1-8, 2007.

Sturman MM, Vaillancourt DE, Metman LV, Sierens DK, Bakay RA, Corcos DM.  Deep brain stimulation and medication for parkinsonian tremor during secondary tasks.  Movement Disorders 22(8):1157-63, 2007.

Collier TJ, Lipton J, Daley BF, Palfi S, Chu Y, Sortwell C, Bakay RA, Sladek JR Jr., Kordower JH.  Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism.  Neurobiol Dis 26(1):56-65, 2007.

Shapiro MB, Vaillancourt DE, Sturman MM, Verhagen L, Bakay RAE, Corcos DM.  Effects of STN DBS on rigidity in Parkinson’s disease.  IEEE Transactions of Neural Systems and Rehabilitation Engineering Special Issue on Deep Brain Stimulation. 15(2):173-81, 2007.

Pilitsis JG, Chu Y, Kordower J, Bergen DC, Cochran EJ, Bakay RAE, et al. Post-mortem study of deep brain stimulation of the anterior thalamus.  Neurosurgery (in press), 2007. 

Pallavaram S, Bakay RAE.  Inter-surgeon variability in the selection of anterior and posterior commissures and its potential effects on target localization. Stereotactic and Funcational Neurosurgery (in press), 2007.

Pilitsis JG, Bakay RAE.  Deep brain stimulation for psychiatric disorders. sychopharm Review 2007 42(9).

Diederich N, Bakay RAE, Verhagen L, Alesch F. VIM stimulation in complex tremor syndromes.  Stereotactic and Functional Neurosurgery (in press), 2008.

Pilitsis J, Bakay RAE, Verhagen L.  Factors involved in long-term efficacy of deep brain stimulation of the thalamus for essential tremor.  J Neurosurg (in press), 2008.

Sturman M, Bakay RAE, Verhagen L, Corcos D, Shapiro M.  Effect of short and long term STN stimulation periods on Parkinsonian signs.  Movement Disorders (in press), 2008.

Marks WJ, Verhagen L, Bakay RAE, et al.   A phase I, open-label study of CERE-120 (adeno-associated virus serotype 2 [AAV2]-neurturin [NTN]) to assess the safety and tolerability of intraputaminal delivery to subjects with idiopathic Parkinson’s disease.  The Lancet Neurology (in press), 2008.

Book Chapters

Ribak CE, Shappiro LA, Seress L, Bakay RAE. Alumina Gel Injection Models of Epilepsy in Monkeys, In: Models of Seizures and Epilepsy.  Elsevier Science, Cambridge England 2005, pp. 179-187.

Pilitsis J, Bakay RAE, Lozano AM.  Stimulation and Ablative Treatment for Parkinson’s Disease In: Kordower J, Tuszynski M (eds), CNS Regeneration 2nd Edition:Basic Science and Clinical Advances. Elsevier. Dec 2007.

Bakay, RAE.  Implantable Brain-Computer Interfaces: Neurosurgical Experience and Perspective In: DiLorenzo DJ and Bronzino JD (eds), Neuroengineering.  Dec 2007. pp. 13.1 – 13.12.

Bakay RAE, Kurtz S:  The Thalamus, In: Starr P, Barbaro N, Larson P (eds), Neurosurgical Operative Atlas 2nd Edition: Functional Neurosurgery.  Thieme. In Press.

Pilitsis JG, Bakay RAE.  The future of deep brain stimulation In: Tarsy, Okun, Staff, and Vitek (eds), Deep Brain Stimulation in Neurological and Psychiatric Disorders.  Humana, Totowa, NJ (In press).

Pilitsis JG, Bakay RAE.  Novel neuromodulation strategies in Alzheimer’s and other neurodegenerative disorders In: Krames E, Peckhas PH, Rezai A (eds), Textbook of Neuromodulation.  Blackwell, Boston, MA (In press).

Sierens D, Kutz S, Pilitsis JG, Bakay RAE.  Stereotactic surgery with microelectrode recordings In: Bakay RAE (ed), Movement Disorder Surgery: The Essentials.  Thieme, New York.  (In press)







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