Comparison of two investigational ventricular assist devices

The purpose of this study is comparison of two mechanical devices that provide support as destination therapy to patients who are at risk of imminent death from nonreversible left ventricular failure and who are not heart transplant candidates.

After the device is implanted, patients will be monitored and will learn more about the device so they can be discharged to their homes. These devices are designed to make patients stronger so they are able to resume their normal, everyday activities.

You may be eligible to participate in this study if you:

• Have severe, end-stage heart failure (Class IV classification) and have failed to respond to optical medical management.
• Are not eligible for heart transplantation as determined by the Rush multidisciplinary transplant committee.
• Have a left ventricular ejection fraction (LVEF) less than 25%.
• Have been approved for LVAD implantation as determined by the Rush multidisciplinary transplant committee.

This is a partial list of eligibility requirements. To discuss your specific eligibility, please call the number provided. NOTE: You must have been approved for LVAD implantation by the Rush multidiscplinary transplant committee to participate.