This is a study to evaluate the effects of two FDA approved medications for high blood pressure in patients with renal insufficiency to examine the safety and effectiveness of the two medications on the kidneys.

Participants in this eight-week study will be required to attend eight office visits during that time. However, participants may have to return more often to complete or repeat procedures. Each visit should not take more than an hour.

• History or a new diagnosis of renal impairment
• History or a new diagnosis of hypertension or newly diagnosis