This study will examine the effectiveness of changing immunosuppresive drugs in patients who have had a kidney or liver transplant within the past six months and have developed abnormal glucose levels. Patients will be randomly assigned to either maintain their current medication regimen or change to the study drug. The study will last 26 weeks.

To be eligible, participants must:

• Be at least 18 years old
• Have had a kidney or liver transplant more than two months ago
• Be taking immunosuppressant medication
• Have abnormal glucose levels

This is a partial list of eligibility requirements.