Antihypertensive Treatment of Cerebral Hemorrhage (ATACH-II): ATACH-II is a phase III, randomized, multicenter, concurrently controlled, parallel arms design clinical trial examining blood pressure reduction for hypertension in acute ICH.

Anxiety and Epilepsy Treatment Study: This study is comparing two FDA-approved medications to treat anxiety in subjects with a partial seizure disorder.

CREST-E Huntingtons Disease (HD) Study: The Huntington Study Group (HSG) and Massachusetts General Hospital (Steven M. Hersch, MD, PhD) are conducting a Phase 3 randomized, double-blind, placebo-controlled clinical trial in Huntingtons disease (HD). Approximately 50 clinical sites globally will enroll up to 650 research subjects.

Cervical Dystonia Treatment Study: The purpose of the protocol is to evaluate the efficacy of Dysport using 2 mL dilution compared with placebo for the treatment of cervical dystonia.

Clot Lysis: Evaluated Accelerated Resolution of Intraventricular Hemorrhage: CLEAR-III is a multicenter, international, double-blind, randomized study comparing the long-term functional outcomes of lysing ventricular blood clots using EVD combined with rt-PA against EVD compared with placebo (saline) for the treatment of severe IVH.

Desmoteplase in Subjects With Acute Ischemic Stroke (DIAS-4): DIAS-4 is a multinational, randomized, double-blind, parallel-group, placebo-controlled, phase III study designed to evaluate the efficacy and safety of desmoteplase in subjects with acute ischemic stroke three to nine hours after symptom onset.

Discovery of Biomarkers for Parkinson Disease: The purpose of this observational study is to identify one or more biomarkers of Parkinson disease. The discovery of a biomarker is critical to the development of new and improved treatments for Parkinson disease.

Epilepsy Examination Study: Patients who are candidates for epilepsy surgery are asked to donate a small portion of the brain tissue that will be removed as part of their planned, elective surgery. The purpose of the study is to further our understanding of epilepsy and possibly develop new treatments in the future.

Epilepsy Neuronal Changes Study: Patients who are candidates for epilepsy surgery, during which brain tissue will be taken out as part of the standard surgical procedure, are invited to donate a portion of this brain tissue and medical information about themselves so scientists can examines how epilepsy affects the brain.

Epilepsy Phenome/Genome Project(EPGP): Everyone who volunteers for EPGP will be asked to give a sample of their DNA via a blood draw and answer some questions asked by a study nurse or physician.

Epilepsy and Depression (Interictal Dysphoric Disorder): Study to evaluate the safety and efficacy of medication in the treatment of a form of depression in epilepsy known as interictal dysphoric disorder with or without postictal depressive symptoms.

Epilepsy and Mood: The purpose of this research study is to determine if a particular antiepileptic medication may have these same positive results as some of the other antiepileptic drugs have produced on mood.

Fragile X Study: Premutation Carriers: Researchers are investigating neurological symptoms in male and female carriers of the FXS premutation, and comparing these symptoms to other carriers and noncarriers of the same age.

Glioblastoma Multiforme Vaccine Trial: Vaccine trial for the treatment of glioblastoma multiforme, administered in conjunction with temozolomide and radiation therapy, which is the current, accepted standard of care.

Huntington's Disease Cohort Prospective Registry Study: Enroll-HD is a longitudinal, observational, multinational study that will integrate two existing Huntington's disease (HD) registries, REGISTRY in Europe and COHORT in North America and Australia, while also expanding to include sites in Latin America and Asia.

Huntington's Disease Study: This study is looking at the effects of coenzyme Q10 on the progression of functional decline in Huntington's disease, as well as the long-term safety and tolerability of the study dosage.

Improvement of Motor Symptoms in Parkinson's Disease Study: Open-label study looking at the safety and effect of apomorphine injections (APOKYN) for rapid and reliable improvement of motor symptoms in Parkinsons disease

Levodopa-Induced Dyskinesia in Parkinson Disease Treatment Study: This study will evaluate the safety, effectiveness and tolerability of three dose levels of an extended release treatment of levodopa-induced dyskineisa.

New Transient Ischemic Attack Study: The purpose of this study is to determine whether taking Plavix and aspirin for 90 days immediately following a minor stroke or TIA will decrease the risk for another event.

P-15 Bone Putty Study: The purpose of this study is to evaluate an investigational device used to promote bone growth in cervical fusions.

Parkinson Disease Mild Cognitive Impairment Study: The purpose of this study is to find out whether the study drug is effective in improving memory function, or cognition, in people with mild cognitive impairment in Parkinson disease (PD-MCI).

Parkinson's Disease Cognitive Impairment Study: We are currently studying thinking and memory (cognition) in Parkinson disease. We are recruiting participants with PD, some who have cognitive problems and others who do not. The study involves a clinical evaluation and a scan of your brain with magnetic resonance imaging.

Parkinson's Disease Patch Delivery Effectiveness Study: A double-blind, placebo-controlled study of the effect of patch-delivered therapy on apathy, motor symptoms and mood in subjects with Parkinson disease

Parkinson's Disease and Sleep Disturbance Study: This is a single-center study of the treatment of hallucinations and sleep disturbances in Parkinson disease patients.

Pax Genes in Adult Primary Brain Tumor Study: Patients who are candidates for brain surgery during which brain tumor tissue will be taken out as part of the standard surgical procedure are invited to donate a portion of this tissue and medical information about themselves in order to allow physicians to study brain tumors.

Randomized Multicenter Clinical Trial of Unruptured Brain AVMs (ARUBA): The ARUBA study is a clinical trial to find out better ways of caring for people who have been discovered to have an arteriovenous malformation in the brain that has never bled.

Risk Factors for Women with Cerebral Aneurysm Study: Our study will focus on better understanding why women appear to be at higher risk for the development of cerebral aneurysms.

SURE-PD Study: This study has several purposes. We will look at how safe inosine is in subjects with early Parkinson disease and if it causes side effects. We will also see if inosine can raise urate levels in blood (serum) and incerebrospinal fluid in subjects with early PD.

Spontaneous Intracerebral Hemorrhaging and Diffusion Weighted Imaging: AHADWIICH is a prospective, blinded phase I clinical study funded by the American Heart Association that examines patients with spontaneous ICH in order to determine the presence and effect of DWI lesions on patient outcomes.

Study of Dural Sealant Used in Cranial Procedures: The purpose of this study is to evaluate whether or not an investigational dural sealant can be used safely and effectively to help seal the dura mater after cranial (brain) surgery.

The Use of Intraoperative Image-Guided Navigation During Vertebral Kyphoplasty: Study of the reduction in radiation exposures to patient and surgeon during vertebral kyphoplasty by the use of intraoperative image-guided navigation

Treating Anxiety in Subjects With Epilepsy: A comparison of two FDA-approved medications to treat anxiety in subjects with epilepsy

Treatment of Postural and Gait Dysfunction in Parkinson's Disease: The purpose of this study is to test the drug Chantix on patients with Parkinson's disease and to see if it can improve balance impairment and postural instability often found in that patient population.

Using Computer Software to Study Alzheimer's Disease: Study to evaluate the ability of a novel software program to diagnose and track the progression of Alzheimer's disease using MEG/EEG