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Health Information Anatomy of the Skin

Anatomy of the Skin

Anatomy of the skin

Facts about the skin:

The skin is the body''s largest organ, covering the entire body. In addition to serving as a protective shield against heat, light, injury, and infection, the skin also:

  • regulates body temperature.
  • stores water and fat.
  • is a sensory organ.
  • prevents water loss.
  • prevents entry of bacteria.
Throughout the body, the skin''s characteristics (thickness, color, texture) vary. For instance, the head contains more hair follicles than anywhere else, while the soles of the feet contain none. In addition, the soles of the feet and the palms of the hands are much thicker. The skin is made up of the following layers, with each layer performing specific functions:
  • epidermis
  • dermis
  • subcutaneous fat layer
epidermis The epidermis is the thin outer layer of the skin and consists of three parts:
  • stratum corneum (horny layer)
    This layer consists of fully mature keratinocytes which contain fibrous proteins (keratins). The outermost layer is continuously shed. The stratum corneum prevents the entry of most foreign substances as well as the loss of fluid from the body.
  • keratinocytes (squamous cells)
    This layer, just beneath the stratum corneum, contains living keratinocytes (squamous cells), which mature and form the stratum corneum.
  • basal layer
    The basal layer is the deepest layer of the epidermis, containing basal cells. Basal cells continually divide, forming new keratinocytes that replace the cells that are shed from the skin''s surface.

The epidermis also contains melanocytes, which are cells that produce melanin (skin pigment).

dermis The dermis is the middle layer of the skin. The dermis contains the following:

  • blood vessels
  • lymph vessels
  • hair follicles
  • sweat glands
  • collagen bundles
  • fibroblasts
  • nerves
The dermis is held together by a protein called collagen, made by fibroblasts. This layer also contains pain and touch receptors.
subcutis The subcutis is the deepest layer of skin. The subcutis, consisting of a network of collagen and fat cells, helps conserve the body''s heat and protects the body from injury by acting as a shock absorber.

The Dermatology Programs and Services at Rush

Dermatology specialists at Rush University Medical Center in Chicago offer comprehensive care for common and rare skin, hair and nail diseases. Offering care for people of all ages, our dermatologists are leading authorities in skin care whose expertise draws patients from all over the Midwest. The dermatology team at Rush offers safe and innovative treatments based on years of experience as well as the latest scientific research.

Click here to visit our Department of Dermatology.

Services Provided

Comprehensive dermatology services for adults and children include:

  • Innovative treatments for various dermatologic conditions
    such as
    • Acne
    • Eczema (atopic dermatitis)
    • Psoriasis
    • Vitiligo
  • State-of-the-art treatments for all forms of skin cancer include:
    • The CTCL Clinic provides multidisciplinary care for people with a rare type of cancer called cutaneous T-cell lymphoma (CTCL). Treatments include extracorporeal photophoresis, one of the most effective treatments for patients with this disease.
    • The Melanoma Surveillance Clinic provides innovative intervention and treatment strategies for melanoma, including the use of photographic surveillance to track high-risk moles over time.
    • Mohs micrographic surgery (MMS) Clinic provides Mohs surgery, which has the highest cure rate of any procedure for skin cancer. During Mohs surgery, the surgeon uses a microscope to remove the very last traces of cancer cells.
  • The Cosmetic Dermatology Program provides:
    • Antiaging therapies, such as Botox and collagen injections.
    • Chemical peels and microdermabrasion to make skin smoother and improve acne, wrinkles and skin discoloration.
    • Advanced laser therapy to decrease excess hair growth and reduce lines and scars.
    • Varicose vein treatments, including laser therapy and sclerotherapy, which involves the injection of special solutions into the veins to reduce their appearance.

In addition to the services above, the department tests the efficacy of new treatments for different skin diseases through its Clinical Pharmacology Unit. Clinical studies are complemented by a basic science laboratory, where investigators are conducting state-of-the-art research on mast cell biology and mastocytosis.

Finding a specialist at Rush:

To find a dermatologist at Rush click here.

Or make an appointment with a doctor at Rush by calling our toll-free physician referral number:

  • (888) 352-RUSH.

To reach the hospital operator, call (312) 942-5000. If you have difficulty hearing, call (312) 942-2207 (TTY/TTD).

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